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Aliases for MIR4743 Gene

Subcategory (RNA class) for MIR4743 Gene

miRNA

Quality Score for this RNA gene is

2

Aliases for MIR4743 Gene

  • MicroRNA 4743 2 3
  • Hsa-Mir-4743 3

External Ids for MIR4743 Gene

Previous GeneCards Identifiers for MIR4743 Gene

  • GC18U900661
  • GC18P046198

Summaries for MIR4743 Gene

Entrez Gene Summary for MIR4743 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4743 Gene

MIR4743 (MicroRNA 4743) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4743 Gene

Genomics for MIR4743 Gene

Regulatory Elements for MIR4743 Gene

Enhancers for MIR4743 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around MIR4743 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR4743 Gene

Chromosome:
18
Start:
48,670,600 bp from pter
End:
48,670,668 bp from pter
Size:
69 bases
Orientation:
Plus strand

Genomic View for MIR4743 Gene

Genes around MIR4743 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4743 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4743 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4743 Gene

Proteins for MIR4743 Gene

Post-translational modifications for MIR4743 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4743 Gene

Domains & Families for MIR4743 Gene

Gene Families for MIR4743 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4743: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4743 Gene

Function for MIR4743 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4743 Gene

Localization for MIR4743 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4743 Gene

Pathways & Interactions for MIR4743 Gene

SuperPathways for MIR4743 Gene

No Data Available

Interacting Proteins for MIR4743 Gene

Gene Ontology (GO) - Biological Process for MIR4743 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4743 Gene

Drugs & Compounds for MIR4743 Gene

No Compound Related Data Available

Transcripts for MIR4743 Gene

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4743 Gene

No ASD Table

Relevant External Links for MIR4743 Gene

GeneLoc Exon Structure for
MIR4743
ECgene alternative splicing isoforms for
MIR4743

No data available for mRNA/cDNA for MIR4743 Gene

Expression for MIR4743 Gene

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MIR4743 Gene

Orthologs for MIR4743 Gene

No data available for Orthologs and Evolution for MIR4743 Gene

Paralogs for MIR4743 Gene

No data available for Paralogs for MIR4743 Gene

Variants for MIR4743 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR4743 Gene

Variant ID Type Subtype PubMed ID
nsv833642 CNV Gain 17160897
nsv833643 CNV Gain 17160897
nsv909619 CNV Gain 21882294
nsv2291 CNV Insertion 18451855
nsv509694 CNV Insertion 20534489

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Variation tolerance and Relevant External Links for MIR4743 Gene

Disorders for MIR4743 Gene

Relevant External Links for MIR4743

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR4743

No disorders were found for MIR4743 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4743 Gene

Publications for MIR4743 Gene

  1. Differential expression of microRNA in peripheral blood mononuclear cells as specific biomarker for major depressive disorder patients. (PMID: 25201637) Fan H.M. … Lu J. (J Psychiatr Res 2014) 3 67
  2. Transcription factors are targeted by differentially expressed miRNAs in primates. (PMID: 22454130) Dannemann M. … Kelso J. (Genome Biol Evol 2012) 3
  3. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H. … Rovira C. (Cancer Res. 2011) 3
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3

Products for MIR4743 Gene

Sources for MIR4743 Gene

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