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Aliases for MIR4734 Gene

Subcategory (RNA class) for MIR4734 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4734 Gene

  • MicroRNA 4734 2 3
  • Hsa-Mir-4734 3

External Ids for MIR4734 Gene

Previous GeneCards Identifiers for MIR4734 Gene

  • GC17U901649
  • GC17M036863

Summaries for MIR4734 Gene

Entrez Gene Summary for MIR4734 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4734 Gene

MIR4734 (MicroRNA 4734) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4734 Gene

Genomics for MIR4734 Gene

Genomic Location for MIR4734 Gene

Start:
38,702,262 bp from pter
End:
38,702,331 bp from pter
Size:
70 bases
Orientation:
Minus strand

Genomic View for MIR4734 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR4734 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4734 Gene

No data available for Regulatory Elements for MIR4734 Gene

Proteins for MIR4734 Gene

Post-translational modifications for MIR4734 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4734 Gene

Domains for MIR4734 Gene

Gene Families for MIR4734 Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4734: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4734 Gene

Function for MIR4734 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR4734 Gene

Localization for MIR4734 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4734 Gene

Pathways for MIR4734 Gene

SuperPathways for MIR4734 Gene

No Data Available

Interacting Proteins for MIR4734 Gene

Gene Ontology (GO) - Biological Process for MIR4734 Gene

None

No data available for Pathways by source for MIR4734 Gene

Transcripts for MIR4734 Gene

mRNA/cDNA for MIR4734 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4734 Gene

No ASD Table

Relevant External Links for MIR4734 Gene

GeneLoc Exon Structure for
MIR4734
ECgene alternative splicing isoforms for
MIR4734

Expression for MIR4734 Gene

mRNA expression in normal human tissues for MIR4734 Gene

genes like me logo Genes that share expressions with MIR4734: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for MIR4734 Gene

Orthologs for MIR4734 Gene

Evolution for MIR4734 Gene

ENSEMBL:
Gene Tree for MIR4734 (if available)
TreeFam:
Gene Tree for MIR4734 (if available)

No data available for Orthologs for MIR4734 Gene

Paralogs for MIR4734 Gene

No data available for Paralogs for MIR4734 Gene

Variants for MIR4734 Gene

Sequence variations from dbSNP and Humsavar for MIR4734 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type MAF
rs58158837 -- 38,701,771(+) CTAAG(C/G)TTAGT downstream-variant-500B
rs74595262 -- 38,702,185(+) ACCCT(C/T)CAGCC downstream-variant-500B
rs77971615 -- 38,702,890(+) TTGAA(C/T)TTGAC upstream-variant-2KB
rs79736325 -- 38,702,853(+) GTGGG(C/T)GCTCA upstream-variant-2KB
rs113862415 -- 38,702,214(+) GAACC(A/G)GCGAG downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for MIR4734 Gene

Variant ID Type Subtype PubMed ID
nsv908194 CNV Loss 21882294
nsv833438 CNV Loss 17160897
nsv908196 CNV Loss 21882294
dgv3160n71 CNV Loss 21882294
nsv470585 CNV Loss 18288195

Relevant External Links for MIR4734 Gene

HapMap Linkage Disequilibrium report
MIR4734

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MIR4734 Gene

Disorders for MIR4734 Gene

No disorders were found for MIR4734 Gene.

No data available for UniProtKB/Swiss-Prot for MIR4734 Gene

Publications for MIR4734 Gene

  1. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  2. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H. … Rovira C. (Cancer Res. 2011) 3

Products for MIR4734 Gene

Sources for MIR4734 Gene

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