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Aliases for MIR4733 Gene

Subcategory (RNA class) for MIR4733 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4733 Gene

  • MicroRNA 4733 2 3 5
  • Hsa-Mir-4733 3

External Ids for MIR4733 Gene

Previous GeneCards Identifiers for MIR4733 Gene

  • GC17U901634
  • GC17M029425

Summaries for MIR4733 Gene

Entrez Gene Summary for MIR4733 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4733 Gene

MIR4733 (MicroRNA 4733) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4733 Gene

Genomics for MIR4733 Gene

Regulatory Elements for MIR4733 Gene

Enhancers for MIR4733 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH17F031092 0.4 Ensembl 0.8 +1.6 1625 0.4 ELF3 ZNF316 PKNOX1 JUND RFX1 IKZF1 RAD21 MIR4733 LOC646030
GH17F031093 0.4 ENCODE 0.8 -0.9 -890 2.8 ARID4B SIN3A FEZF1 DMAP1 ZNF2 YY1 FOS ZNF263 SP3 SMARCB1 ENSG00000264456 RNF135 SUZ12 UTP6 SH3GL1P2 SH3GL1P1 ATAD5 DPRXP4 OMG MIR4733
GH17F031066 1.4 Ensembl ENCODE 0.3 +26.4 26377 2.3 TBP CTCF CBX3 JUN RAD21 ZNF121 GATA3 SMC3 NR2F6 FOS RAB11FIP4 ATAD5 RPS17P3 LOC101927093 LOC646030 MIR4733
GH17F031073 0.2 ENCODE 0.3 +20.6 20613 0.7 ZNF121 ZBTB33 LOC646030 MIR4733
GH17F031071 0.5 ENCODE 0.3 +22.2 22225 2.0 KLF1 INSM2 FEZF1 CEBPG ZEB1 ZFHX2 GATA3 CTBP1 PATZ1 PRDM10 OMG LOC646030 MIR4733
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around MIR4733 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR4733 Gene

Chromosome:
17
Start:
31,094,350 bp from pter
End:
31,094,425 bp from pter
Size:
76 bases
Orientation:
Minus strand

Genomic View for MIR4733 Gene

Genes around MIR4733 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4733 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4733 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4733 Gene

Proteins for MIR4733 Gene

Post-translational modifications for MIR4733 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4733 Gene

Domains & Families for MIR4733 Gene

Gene Families for MIR4733 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4733: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4733 Gene

Function for MIR4733 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4733 Gene

Localization for MIR4733 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4733 Gene

Pathways & Interactions for MIR4733 Gene

SuperPathways for MIR4733 Gene

No Data Available

Interacting Proteins for MIR4733 Gene

Gene Ontology (GO) - Biological Process for MIR4733 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4733 Gene

Transcripts for MIR4733 Gene

mRNA/cDNA for MIR4733 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4733 Gene

No ASD Table

Relevant External Links for MIR4733 Gene

GeneLoc Exon Structure for
MIR4733
ECgene alternative splicing isoforms for
MIR4733

Expression for MIR4733 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4733 Gene:

MIR4733
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR4733 Gene

Orthologs for MIR4733 Gene

Evolution for MIR4733 Gene

ENSEMBL:
Gene Tree for MIR4733 (if available)
TreeFam:
Gene Tree for MIR4733 (if available)

No data available for Orthologs for MIR4733 Gene

Paralogs for MIR4733 Gene

No data available for Paralogs for MIR4733 Gene

Variants for MIR4733 Gene

Sequence variations from dbSNP and Humsavar for MIR4733 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type
rs786203307 Pathogenic 31,095,364(+) TCGAC(G/T)AGCAG upstream-variant-2KB, reference, stop-gained
rs876658658 Pathogenic 31,095,340(+) GGGTC(C/T)AGGCC upstream-variant-2KB, reference, stop-gained
rs556823296 Likely benign 31,095,288(+) CCGCC(C/G)CCCCC upstream-variant-2KB, utr-variant-5-prime
rs786203866 Likely benign 31,095,345(+) CAGGC(C/T)GTGGT upstream-variant-2KB, reference, synonymous-codon
rs876660128 Likely benign 31,095,315(+) ATGGC(C/T)GCGCA upstream-variant-2KB, reference, synonymous-codon

Relevant External Links for MIR4733 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4733

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR4733 Gene

Disorders for MIR4733 Gene

Relevant External Links for MIR4733

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR4733

No disorders were found for MIR4733 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4733 Gene

Publications for MIR4733 Gene

  1. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H. … Rovira C. (Cancer Res. 2011) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4733 Gene

Sources for MIR4733 Gene

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