Free for academic non-profit institutions. Other users need a Commercial license

Aliases for MIR4732 Gene

Subcategory (RNA class) for MIR4732 Gene

lncRNA

Quality Score for this RNA gene is

3.2

Aliases for MIR4732 Gene

  • MicroRNA 4732 2 3 5
  • Hsa-Mir-4732 3
  • Mir-4732 3

External Ids for MIR4732 Gene

ORGUL Members for MIR4732 Gene

Previous GeneCards Identifiers for MIR4732 Gene

  • GC17U901633
  • GC17M027197
  • GC17M027269
  • GC17M028863

Summaries for MIR4732 Gene

Entrez Gene Summary for MIR4732 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4732 Gene

MIR4732 (MicroRNA 4732) is an RNA Gene, and is affiliated with the lncRNA class.

fRNAdb sequence ontologies for MIR4732 Gene

  • nc_conserved_region: Non-coding region of sequence similarity by descent from a common ancestor.

View fRNAdb secondary structures for MIR4732

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR4732 Gene

Genomics for MIR4732 Gene

Regulatory Elements for MIR4732 Gene

Enhancers for MIR4732 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
- Elite enhancer/Elite enhancer-gene association

Enhancers around MIR4732 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR4732 Gene

Chromosome:
17
Start:
28,861,072 bp from pter
End:
28,861,966 bp from pter
Size:
895 bases
Orientation:
Minus strand

Genomic View for MIR4732 Gene

Genes around MIR4732 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4732 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4732 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4732 Gene

Proteins for MIR4732 Gene

Post-translational modifications for MIR4732 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4732 Gene

Domains & Families for MIR4732 Gene

Gene Families for MIR4732 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4732: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4732 Gene

Function for MIR4732 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4732 Gene

Localization for MIR4732 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4732 Gene

Pathways & Interactions for MIR4732 Gene

SuperPathways for MIR4732 Gene

No Data Available

Interacting Proteins for MIR4732 Gene

Gene Ontology (GO) - Biological Process for MIR4732 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4732 Gene

Drugs & Compounds for MIR4732 Gene

No Compound Related Data Available

Transcripts for MIR4732 Gene

fRNAdb Secondary structures for MIR4732 Gene

  • FR102080

mRNA/cDNA for MIR4732 Gene

(4) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4732 Gene

No ASD Table

Relevant External Links for MIR4732 Gene

GeneLoc Exon Structure for
MIR4732
ECgene alternative splicing isoforms for
MIR4732

Expression for MIR4732 Gene

mRNA differential expression in normal tissues according to GTEx for MIR4732 Gene

This gene is overexpressed in Whole Blood (x38.3) and Spleen (x7.4).

NURSA nuclear receptor signaling pathways regulating expression of MIR4732 Gene:

MIR4732

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR4732 Gene

Orthologs for MIR4732 Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR4732 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia bta-mir-144 35
  • 92 (a)
OneToOne
dog
(Canis familiaris)
Mammalia cfa-mir-144 35
  • 93 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia mdo-mir-144 35
  • 86 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mir144 35
  • 98 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia oan-mir-144 35
  • 58 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-144 35
  • 99 (a)
OneToOne
chicken
(Gallus gallus)
Aves gga-mir-144 35
  • 80 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii dre-mir-144 35
  • 72 (a)
OneToOne
Species where no ortholog for MIR4732 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MIR4732 Gene

ENSEMBL:
Gene Tree for MIR4732 (if available)
TreeFam:
Gene Tree for MIR4732 (if available)

Paralogs for MIR4732 Gene

No data available for Paralogs for MIR4732 Gene

Variants for MIR4732 Gene

Sequence variations from dbSNP and Humsavar for MIR4732 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type
rs143788443 -- 28,863,642(+) GATCC(A/G)CCCGC upstream-variant-2KB
rs534667532 -- 28,863,678(+) ACAGG(C/T)GTGAG upstream-variant-2KB
rs537047509 -- 28,863,623(+) CGAAC(C/T)CTTGA upstream-variant-2KB
rs553224379 -- 28,863,679(+) CAGGC(C/G)TGAGC upstream-variant-2KB
rs567336273 -- 28,863,645(+) CCGCC(C/T)GCCTC upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR4732 Gene

Variant ID Type Subtype PubMed ID
esv3640315 CNV loss 21293372

Relevant External Links for MIR4732 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4732

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4732 Gene

Disorders for MIR4732 Gene

Relevant External Links for MIR4732

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR4732

No disorders were found for MIR4732 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4732 Gene

Publications for MIR4732 Gene

  1. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A. … Griffiths-Jones S. (Nucleic Acids Res. 2011) 3 65
  2. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H. … Rovira C. (Cancer Res. 2011) 3 65
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 65
  4. Identification and classification of conserved RNA secondary structures in the human genome. (PMID: 16628248) Pedersen J.S. … Haussler D. (PLoS Comput. Biol. 2006) 1
  5. RNAdb--a comprehensive mammalian noncoding RNA database. (PMID: 15608161) Pang K.C. … Mattick J.S. (Nucleic Acids Res. 2005) 1

Products for MIR4732 Gene

Sources for MIR4732 Gene

Content
Loading form....