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Aliases for MIR4718 Gene

Subcategory (RNA class) for MIR4718 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4718 Gene

  • MicroRNA 4718 2 3 5
  • Hsa-Mir-4718 3

External Ids for MIR4718 Gene

Previous GeneCards Identifiers for MIR4718 Gene

  • GC16U901345
  • GC16P012816

Summaries for MIR4718 Gene

Entrez Gene Summary for MIR4718 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4718 Gene

MIR4718 (MicroRNA 4718) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4718 Gene

Genomics for MIR4718 Gene

Regulatory Elements for MIR4718 Gene

Enhancers for MIR4718 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH16F012728 0.9 Ensembl ENCODE 0.4 +9.2 9219 1.9 JUN MAFK CPPED1 ENSG00000238685 MIR4718 LOC105371090
GH16F012683 0.3 FANTOM5 0.3 -37.2 -37179 0.2 CPPED1 LOC105371088 MIR4718
GH16F012680 0.4 ENCODE 0.3 -39.7 -39691 0.7 LOC105371088 MIR4718
GH16F012674 1 FANTOM5 Ensembl ENCODE 0.2 -44.9 -44856 2.5 BCOR ESRRA TAL1 JUN ZMYM3 NCOR1 EED NR2F6 TRIM24 CREM CPPED1 LOC105371088 MIR4718
GH16F012679 0.2 ENCODE 0.2 -40.8 -40801 0.1 ZGPAT ZNF792 ADNP TCF7L2 LOC105371088 MIR4718
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around MIR4718 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR4718 Gene

Chromosome:
16
Start:
12,720,321 bp from pter
End:
12,720,371 bp from pter
Size:
51 bases
Orientation:
Plus strand

Genomic View for MIR4718 Gene

Genes around MIR4718 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4718 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4718 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4718 Gene

Proteins for MIR4718 Gene

Post-translational modifications for MIR4718 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4718 Gene

Domains & Families for MIR4718 Gene

Gene Families for MIR4718 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4718: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4718 Gene

Function for MIR4718 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4718 Gene

Localization for MIR4718 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4718 Gene

Pathways & Interactions for MIR4718 Gene

SuperPathways for MIR4718 Gene

No Data Available

Interacting Proteins for MIR4718 Gene

Gene Ontology (GO) - Biological Process for MIR4718 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4718 Gene

Transcripts for MIR4718 Gene

mRNA/cDNA for MIR4718 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4718 Gene

No ASD Table

Relevant External Links for MIR4718 Gene

GeneLoc Exon Structure for
MIR4718
ECgene alternative splicing isoforms for
MIR4718

Expression for MIR4718 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4718 Gene:

MIR4718
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR4718 Gene

Orthologs for MIR4718 Gene

Evolution for MIR4718 Gene

ENSEMBL:
Gene Tree for MIR4718 (if available)
TreeFam:
Gene Tree for MIR4718 (if available)

No data available for Orthologs for MIR4718 Gene

Paralogs for MIR4718 Gene

No data available for Paralogs for MIR4718 Gene

Variants for MIR4718 Gene

Sequence variations from dbSNP and Humsavar for MIR4718 Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type
rs112255992 -- 12,719,724(+) GAGAT(C/G)AGGAG intron-variant, upstream-variant-2KB
rs113825564 -- 12,718,691(+) GGAGC(A/G)GTGGC intron-variant, upstream-variant-2KB
rs11642271 -- 12,720,817(+) GCTTA(A/G)TTTAC intron-variant, downstream-variant-500B
rs117074493 -- 12,718,558(+) AAAAA(A/G)AAAGA intron-variant, upstream-variant-2KB
rs118092906 -- 12,719,672(+) ACTCA(C/T)GCCTG intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR4718 Gene

Variant ID Type Subtype PubMed ID
nsv1052802 CNV loss 25217958
nsv1053617 CNV loss 25217958

Relevant External Links for MIR4718 Gene

Human Gene Mutation Database (HGMD)
MIR4718
SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4718

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4718 Gene

Disorders for MIR4718 Gene

Relevant External Links for MIR4718

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR4718

No disorders were found for MIR4718 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4718 Gene

Publications for MIR4718 Gene

  1. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H. … Rovira C. (Cancer Res. 2011) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4718 Gene

Sources for MIR4718 Gene

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