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Aliases for MIR4715 Gene

Subcategory (RNA class) for MIR4715 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR4715 Gene

  • MicroRNA 4715 2 3 5
  • Hsa-Mir-4715 3

External Ids for MIR4715 Gene

Previous GeneCards Identifiers for MIR4715 Gene

  • GC15U901386
  • GC15M026096

Summaries for MIR4715 Gene

Entrez Gene Summary for MIR4715 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4715 Gene

MIR4715 (MicroRNA 4715) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4715 Gene

Genomics for MIR4715 Gene

Regulatory Elements for MIR4715 Gene

Enhancers for MIR4715 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH15F025844 1.4 FANTOM5 Ensembl ENCODE 0.8 +0.6 593 6.9 ATF1 PKNOX1 INSM2 KLF17 ARID4B ZNF48 RAD21 RARA GLIS2 ZNF366 RPL5P1 LOC105370738 UBE3A MIR4715 GC15P025818
GH15F025852 0.4 FANTOM5 0.8 -3.9 -3943 0.1 CEBPA CEBPG MIR4715 ATP10A
GH15F025858 1.1 FANTOM5 ENCODE 0.4 -12.5 -12527 5.7 HDAC2 POLR2A ZMYM3 NR3C1 NR2F2 LOC105370738 ATP10A UBE3A MIR4715
GH15F025828 0.8 Ensembl ENCODE 0.3 +18.0 17954 4.0 JUND ATF3 BHLHE40 FOS MAFK ATF2 ATP10A GC15P025818 MIR4715
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around MIR4715 on UCSC Golden Path with GeneCards custom track

Promoters for MIR4715 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00001793168 -1575 1201 PKNOX1 ARID4B ZNF48 RAD21 RARA GLIS2 ZNF366 SCRT2 FOS CREM

Genomic Location for MIR4715 Gene

Chromosome:
15
Start:
25,848,747 bp from pter
End:
25,848,825 bp from pter
Size:
79 bases
Orientation:
Minus strand

Genomic View for MIR4715 Gene

Genes around MIR4715 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4715 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4715 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4715 Gene

ORGUL Member Location for MIR4715 Gene

ORGUL Member Location for MIR4715 gene

Proteins for MIR4715 Gene

Post-translational modifications for MIR4715 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4715 Gene

Domains & Families for MIR4715 Gene

Gene Families for MIR4715 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4715: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4715 Gene

Function for MIR4715 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4715 Gene

Localization for MIR4715 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4715 Gene

Pathways & Interactions for MIR4715 Gene

SuperPathways for MIR4715 Gene

No Data Available

Interacting Proteins for MIR4715 Gene

Gene Ontology (GO) - Biological Process for MIR4715 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4715 Gene

Transcripts for MIR4715 Gene

mRNA/cDNA for MIR4715 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4715 Gene

No ASD Table

Relevant External Links for MIR4715 Gene

GeneLoc Exon Structure for
MIR4715
ECgene alternative splicing isoforms for
MIR4715

Expression for MIR4715 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR4715 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4715 Gene:

MIR4715
genes like me logo Genes that share expression patterns with MIR4715: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR4715 Gene

Orthologs for MIR4715 Gene

Evolution for MIR4715 Gene

ENSEMBL:
Gene Tree for MIR4715 (if available)
TreeFam:
Gene Tree for MIR4715 (if available)

No data available for Orthologs for MIR4715 Gene

Paralogs for MIR4715 Gene

No data available for Paralogs for MIR4715 Gene

Variants for MIR4715 Gene

Sequence variations from dbSNP and Humsavar for MIR4715 Gene

SNP ID Clin Chr 15 pos Sequence Context AA Info Type
rs111862725 -- 25,849,845(+) TTTCC(-/A)AAAAA intron-variant, upstream-variant-2KB
rs112115225 -- 25,850,646(+) CTCCC(C/G/T)CCCCA intron-variant, upstream-variant-2KB
rs112829146 -- 25,850,508(+) GTGGC(A/C)ACACC intron-variant, upstream-variant-2KB
rs113731251 -- 25,850,444(+) GGCCC(C/T)GGCTG intron-variant, upstream-variant-2KB
rs113949350 -- 25,848,383(+) TCCTG(A/G)TCTCA intron-variant, downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for MIR4715 Gene

Variant ID Type Subtype PubMed ID
esv3569331 CNV gain 25503493

Relevant External Links for MIR4715 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4715

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4715 Gene

Disorders for MIR4715 Gene

Relevant External Links for MIR4715

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR4715

No disorders were found for MIR4715 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4715 Gene

Publications for MIR4715 Gene

  1. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H. … Rovira C. (Cancer Res. 2011) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4715 Gene

Sources for MIR4715 Gene

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