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Aliases for MIR4712 Gene

Subcategory (RNA class) for MIR4712 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4712 Gene

  • MicroRNA 4712 2 3
  • GABPB1 Antisense RNA 1 5
  • Hsa-Mir-4712 3
  • GABPB1-AS1 5

External Ids for MIR4712 Gene

Previous GeneCards Identifiers for MIR4712 Gene

  • GC15U901409
  • GC15P050656

Summaries for MIR4712 Gene

Entrez Gene Summary for MIR4712 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4712 Gene

MIR4712 (MicroRNA 4712) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4712 Gene

Genomics for MIR4712 Gene

Regulatory Elements for MIR4712 Gene

Enhancers for MIR4712 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH15F050906 1.2 ENCODE 20.8 +554.3 554320 6.2 PKNOX1 ARNT CREB3L1 MLX WRNIP1 ZFP64 ARID4B SIN3A DMAP1 YY1 AP4E1 ENSG00000259715 MIR4712 TRPM7 ENSG00000259298 USP8 ENSG00000259618 RPS20P34 DCAF13P3 SPPL2A
GH15F050676 1.2 Ensembl ENCODE 15.1 +322.0 321959 2.1 CTCF HDAC1 KLF1 PKNOX1 ATF1 JUN INSM2 KLF17 ZBTB40 RAD21 MIR4712 ENSG00000259298 ENSG00000259715 DCAF13P3 SPPL2A USP8 ENSG00000259618 TRPM7 GC15P050634
GH15F050349 0.2 ENCODE 13.1 -1.7 -1691 8.3 HDGF PKNOX1 ARNT CREB3L1 MLX WRNIP1 ARID4B SIN3A FEZF1 DMAP1 GABPB1-AS1 ENSG00000259715 USP8 AHCYP7 ENSG00000259701 DCAF13P3 MIR4712 ENSG00000259298 FGF7 ENSG00000259618
GH15F050390 0.8 Ensembl ENCODE 12 +37.0 36953 2.6 CTCF BRD4 CEBPG ZNF121 ZNF316 EED ETV6 NFE2 FOS MAFK GABPB1-AS1 USP8 MIR4712 SLC27A2 GC15P050389 AHCYP7
GH15F050318 0.2 Ensembl 11.9 -36.3 -36259 0.2 SMARCA4 POLR2A GABPB1-AS1 MIR4712 GC15P050317 GC15M050350 RNU6-94P
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around MIR4712 on UCSC Golden Path with GeneCards custom track

Promoters for MIR4712 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000407797 -259 5001 PKNOX1 ARNT CREB3L1 MLX WRNIP1 ARID4B SIN3A FEZF1 DMAP1 ZNF2

Genomic Location for MIR4712 Gene

Chromosome:
15
Start:
50,354,959 bp from pter
End:
50,372,202 bp from pter
Size:
17,244 bases
Orientation:
Plus strand

Genomic View for MIR4712 Gene

Genes around MIR4712 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4712 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4712 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4712 Gene

Proteins for MIR4712 Gene

Post-translational modifications for MIR4712 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4712 Gene

Domains & Families for MIR4712 Gene

Gene Families for MIR4712 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4712: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4712 Gene

Function for MIR4712 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4712 Gene

Localization for MIR4712 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4712 Gene

Pathways & Interactions for MIR4712 Gene

SuperPathways for MIR4712 Gene

No Data Available

Interacting Proteins for MIR4712 Gene

Gene Ontology (GO) - Biological Process for MIR4712 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4712 Gene

Transcripts for MIR4712 Gene

mRNA/cDNA for MIR4712 Gene

(7) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4712 Gene

No ASD Table

Relevant External Links for MIR4712 Gene

GeneLoc Exon Structure for
MIR4712
ECgene alternative splicing isoforms for
MIR4712

Expression for MIR4712 Gene

mRNA expression in normal human tissues for MIR4712 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4712 Gene:

MIR4712
genes like me logo Genes that share expression patterns with MIR4712: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR4712 Gene

Orthologs for MIR4712 Gene

Evolution for MIR4712 Gene

ENSEMBL:
Gene Tree for MIR4712 (if available)
TreeFam:
Gene Tree for MIR4712 (if available)

No data available for Orthologs for MIR4712 Gene

Paralogs for MIR4712 Gene

No data available for Paralogs for MIR4712 Gene

Variants for MIR4712 Gene

Sequence variations from dbSNP and Humsavar for MIR4712 Gene

SNP ID Clin Chr 15 pos Sequence Context AA Info Type
rs111718108 -- 50,360,646(+) AGCTC(A/G)CTGCA downstream-variant-500B
rs114514064 -- 50,358,996(+) GACAC(A/G)AGGTT upstream-variant-2KB
rs117948058 -- 50,358,715(+) TTTAC(A/G)GTAAT downstream-variant-500B, upstream-variant-2KB
rs12910141 -- 50,359,595(+) gccac(C/T)gtgcc upstream-variant-2KB
rs12910160 -- 50,359,606(+) cggcc(C/T)ttttt upstream-variant-2KB

Relevant External Links for MIR4712 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4712

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR4712 Gene

Disorders for MIR4712 Gene

Relevant External Links for MIR4712

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR4712

No disorders were found for MIR4712 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4712 Gene

Publications for MIR4712 Gene

  1. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H. … Rovira C. (Cancer Res. 2011) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4712 Gene

Sources for MIR4712 Gene

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