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Aliases for MIR4710 Gene

Subcategory (RNA class) for MIR4710 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR4710 Gene

  • MicroRNA 4710 2 3 5
  • Hsa-Mir-4710 3
  • Mir-4710 3

External Ids for MIR4710 Gene

Previous GeneCards Identifiers for MIR4710 Gene

  • GC14U901288
  • GC14M105146

Summaries for MIR4710 Gene

Entrez Gene Summary for MIR4710 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4710 Gene

MIR4710 (MicroRNA 4710) is an RNA Gene, and is affiliated with the miRNA class.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4710 Gene

Genomics for MIR4710 Gene

Regulatory Elements for MIR4710 Gene

Enhancers for MIR4710 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH14G104676 1.7 FANTOM5 ENCODE dbSUPER 0.7 -2.6 -2575 7.6 PKNOX1 CREB3L1 ARID4B SIN3A DMAP1 ZNF2 YY1 SLC30A9 ZNF766 ZNF143 RPS20P33 GPR132 ENSG00000256050 ENSG00000270108 PACS2 INF2 AKT1 MIR4710
GH14G104665 1.9 FANTOM5 Ensembl ENCODE dbSUPER 0.4 +11.2 11239 2.9 HDGF YBX1 DMAP1 ZBTB7B ZNF302 ZNF207 FOS SP5 ZHX2 ZNF662 ENSG00000257270 XRCC3 TMEM121 RPS20P33 ENSG00000269940 PACS2 LINC00638 ENSG00000256050 INF2 TMEM179
GH14G104668 0.4 dbSUPER 0.4 +9.1 9076 1.2 SCRT2 TMEM179 LINC02280 MIR4710
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR4710 on UCSC Golden Path with GeneCards custom track

Promoters for MIR4710 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000073700 -251 401 ZNF2 YY1 ZNF766 ZNF143 FOS KLF13 ZNF263 SP3 SP5 REST

Genomic Location for MIR4710 Gene

Chromosome:
14
Start:
104,677,694 bp from pter
End:
104,677,749 bp from pter
Size:
56 bases
Orientation:
Minus strand

Genomic View for MIR4710 Gene

Genes around MIR4710 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4710 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4710 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4710 Gene

ORGUL Member Location for MIR4710 Gene

ORGUL Member Location for MIR4710 gene

Proteins for MIR4710 Gene

Post-translational modifications for MIR4710 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4710 Gene

Domains & Families for MIR4710 Gene

Gene Families for MIR4710 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4710: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4710 Gene

Function for MIR4710 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4710 Gene

Localization for MIR4710 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4710 Gene

Pathways & Interactions for MIR4710 Gene

SuperPathways for MIR4710 Gene

No Data Available

Interacting Proteins for MIR4710 Gene

Gene Ontology (GO) - Biological Process for MIR4710 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4710 Gene

Drugs & Compounds for MIR4710 Gene

No Compound Related Data Available

Transcripts for MIR4710 Gene

mRNA/cDNA for MIR4710 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4710 Gene

No ASD Table

Relevant External Links for MIR4710 Gene

GeneLoc Exon Structure for
MIR4710
ECgene alternative splicing isoforms for
MIR4710

Expression for MIR4710 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4710 Gene:

MIR4710
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4710 Gene

Orthologs for MIR4710 Gene

Evolution for MIR4710 Gene

ENSEMBL:
Gene Tree for MIR4710 (if available)
TreeFam:
Gene Tree for MIR4710 (if available)

No data available for Orthologs for MIR4710 Gene

Paralogs for MIR4710 Gene

No data available for Paralogs for MIR4710 Gene

Variants for MIR4710 Gene

Sequence variations from dbSNP and Humsavar for MIR4710 Gene

SNP ID Clin Chr 14 pos Sequence Context AA Info Type
rs1000092077 -- 104,677,542(+) AGCCA(A/G)GCCAC downstream-variant-500B
rs1000123115 -- 104,677,327(+) GGCCG(A/C)ACCCC downstream-variant-500B
rs1001936651 -- 104,678,221(+) CTTAG(C/T)TTCTG upstream-variant-2KB
rs1003117243 -- 104,677,549(+) CCACA(C/T)GCGGG downstream-variant-500B
rs1003989639 -- 104,678,058(+) GAGCC(C/T)ACCTT upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR4710 Gene

Variant ID Type Subtype PubMed ID
dgv265n27 CNV loss 19166990
dgv3952n54 CNV loss 21841781
dgv3953n54 CNV gain 21841781
esv3635623 CNV gain 21293372
nsv1054574 CNV loss 25217958
nsv456445 CNV loss 19166990
nsv470677 CNV loss 18288195
nsv470678 CNV gain 18288195
nsv566047 CNV loss 21841781
nsv566048 CNV gain 21841781
nsv566051 CNV gain+loss 21841781
nsv952271 CNV deletion 24416366

Relevant External Links for MIR4710 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4710

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4710 Gene

Disorders for MIR4710 Gene

Relevant External Links for MIR4710

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR4710

No disorders were found for MIR4710 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4710 Gene

Publications for MIR4710 Gene

  1. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A. … Griffiths-Jones S. (Nucleic Acids Res. 2011) 3 64
  2. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H. … Rovira C. (Cancer Res. 2011) 3 64
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4710 Gene

Sources for MIR4710 Gene

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