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Aliases for MIR4707 Gene

Subcategory (RNA class) for MIR4707 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR4707 Gene

  • MicroRNA 4707 2 3 5
  • Hsa-Mir-4707 3
  • Mir-4707 3

External Ids for MIR4707 Gene

Previous GeneCards Identifiers for MIR4707 Gene

  • GC14U901292
  • GC14M023430
  • GC14M022960
  • GC14M022948

Summaries for MIR4707 Gene

Entrez Gene Summary for MIR4707 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4707 Gene

MIR4707 (MicroRNA 4707) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are Regulation of PLK1 Activity at G2/M Transition and Organelle biogenesis and maintenance.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4707 Gene

Genomics for MIR4707 Gene

Regulatory Elements for MIR4707 Gene

Enhancers for MIR4707 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH14G022955 1.1 ENCODE 0.7 +0.4 425 2.6 HDGF HNRNPUL1 PKNOX1 MLX CREB3L1 AGO1 ZFP64 ARID4B SIN3A DMAP1 HAUS4 C14orf119 AJUBA PSMB5 PSMB11 CDH24 C14orf93 LOC102724814 ACIN1 MIR4707
GH14G022941 0.7 ENCODE 0.4 +15.9 15943 0.2 ZNF263 CTCF TEAD1 SP5 ARID4B PPARG ZNF48 RAD21 TEAD3 ZNF143 HAUS4 TRR-ACG1-3 MIR4707
GH14G022932 0.6 dbSUPER 0.3 +23.6 23583 1.7 L3MBTL2 KLF17 ZIC2 FOXA1 ATM FOXK2 NBN PCBP1 ZNF600 FOS HAUS4 PRMT5 TRR-ACG1-3 MIR4707
GH14G022933 0.2 ENCODE 0.3 +24.7 24703 0.2 TRR-ACG1-3 MIR4707
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR4707 on UCSC Golden Path with GeneCards custom track

Promoters for MIR4707 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000066667 129 1401 HDGF HNRNPUL1 PKNOX1 MLX CREB3L1 AGO1 ZFP64 ARID4B SIN3A DMAP1

Genomic Location for MIR4707 Gene

Chromosome:
14
Start:
22,956,950 bp from pter
End:
22,957,029 bp from pter
Size:
80 bases
Orientation:
Minus strand

Genomic View for MIR4707 Gene

Genes around MIR4707 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4707 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4707 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4707 Gene

ORGUL Member Location for MIR4707 Gene

ORGUL Member Location for MIR4707 gene

Proteins for MIR4707 Gene

Post-translational modifications for MIR4707 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4707 Gene

Domains & Families for MIR4707 Gene

Gene Families for MIR4707 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4707: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4707 Gene

Function for MIR4707 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4707 Gene

Localization for MIR4707 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4707 Gene

Drugs & Compounds for MIR4707 Gene

No Compound Related Data Available

Transcripts for MIR4707 Gene

mRNA/cDNA for MIR4707 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4707 Gene

No ASD Table

Relevant External Links for MIR4707 Gene

GeneLoc Exon Structure for
MIR4707
ECgene alternative splicing isoforms for
MIR4707

Expression for MIR4707 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR4707 Gene

mRNA differential expression in normal tissues according to GTEx for MIR4707 Gene

This gene is overexpressed in Whole Blood (x6.3).

NURSA nuclear receptor signaling pathways regulating expression of MIR4707 Gene:

MIR4707
genes like me logo Genes that share expression patterns with MIR4707: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4707 Gene

Orthologs for MIR4707 Gene

Evolution for MIR4707 Gene

ENSEMBL:
Gene Tree for MIR4707 (if available)
TreeFam:
Gene Tree for MIR4707 (if available)

No data available for Orthologs for MIR4707 Gene

Paralogs for MIR4707 Gene

No data available for Paralogs for MIR4707 Gene

Variants for MIR4707 Gene

Sequence variations from dbSNP and Humsavar for MIR4707 Gene

SNP ID Clin Chr 14 pos Sequence Context AA Info Type
rs1000231326 -- 22,958,978(+) AAAAA(C/T)TAAAA upstream-variant-2KB
rs1001041001 -- 22,958,732(+) TGTAA(G/T)CCCAG upstream-variant-2KB
rs1001113098 -- 22,959,009(+) GGGTG(C/T)AGTGG upstream-variant-2KB
rs1002683004 -- 22,956,688(+) TTACA(C/G)GCTGC intron-variant, downstream-variant-500B
rs1002760185 -- 22,957,196(+) ACGGG(G/T)GCGCG upstream-variant-2KB

Relevant External Links for MIR4707 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4707

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR4707 Gene

Disorders for MIR4707 Gene

Relevant External Links for MIR4707

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR4707

No disorders were found for MIR4707 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4707 Gene

Publications for MIR4707 Gene

  1. Long Noncoding RNA LOC100129973 Suppresses Apoptosis by Targeting miR-4707-5p and miR-4767 in Vascular Endothelial Cells. (PMID: 26887505) Lu W. … Miao J.Y. (Sci Rep 2016) 3 64
  2. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A. … Griffiths-Jones S. (Nucleic Acids Res. 2011) 3 64
  3. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H. … Rovira C. (Cancer Res. 2011) 3 64
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4707 Gene

Sources for MIR4707 Gene

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