Free for academic non-profit institutions. Other users need a Commercial license

Aliases for MIR4706 Gene

Subcategory (RNA class) for MIR4706 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4706 Gene

  • MicroRNA 4706 2 3 5
  • Hsa-Mir-4706 3
  • Mir-4706 3

External Ids for MIR4706 Gene

Previous GeneCards Identifiers for MIR4706 Gene

  • GC14U901279
  • GC14P065513

Summaries for MIR4706 Gene

Entrez Gene Summary for MIR4706 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4706 Gene

MIR4706 (MicroRNA 4706) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4706 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4706 Gene

Genomics for MIR4706 Gene

Regulatory Elements for MIR4706 Gene

Enhancers for MIR4706 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH14H065042 1.5 Ensembl ENCODE dbSUPER 0.7 -0.8 -828 3 PKNOX1 ATF1 ARNT TCF12 ZNF766 GATA2 ELK1 ATF7 RUNX3 NCOA1 FNTB CHURC1-FNTB CHURC1 MIR4706 PIR35799
GH14H065047 1 Ensembl ENCODE dbSUPER 0.7 +3.4 3363 1 OSR2 PRDM6 FEZF1 KDM1A ZNF843 FNTB CHURC1-FNTB MIR4706 PIR44037
GH14H065045 0.5 FANTOM5 dbSUPER 0.7 +0.9 915 0 FNTB MIR4706 PIR44037
GH14H065019 1 Ensembl ENCODE 0.3 -24.6 -24587 0 SOX13 CTCF TFAP4 FOXA2 SAP130 ARID4B RAD21 ZNF766 SMC3 ZNF143 FNTB CHURC1-FNTB GPX2 PIR35799 MIR4706
GH14H065035 0.7 ENCODE 0.4 -9.5 -9451 0 NFIB MAX REST RAD21 FOXA1 NR2F2 GABPA YY1 E2F1 JUND FNTB CHURC1-FNTB MIR4706 PIR35799
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR4706 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR4706 Gene

Chromosome:
14
Start:
65,044,688 bp from pter
End:
65,044,769 bp from pter
Size:
82 bases
Orientation:
Plus strand

Genomic View for MIR4706 Gene

Genes around MIR4706 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4706 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4706 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4706 Gene

Proteins for MIR4706 Gene

Post-translational modifications for MIR4706 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4706 Gene

Domains & Families for MIR4706 Gene

Gene Families for MIR4706 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4706: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4706 Gene

Function for MIR4706 Gene

Animal Model Products

CRISPR Products

miRNA Products

Clone Products

  • Applied Biological Materials Clones for MIR4706
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4706 Gene

Localization for MIR4706 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4706 Gene

Pathways & Interactions for MIR4706 Gene

SuperPathways for MIR4706 Gene

No Data Available

Interacting Proteins for MIR4706 Gene

Gene Ontology (GO) - Biological Process for MIR4706 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4706 Gene

Drugs & Compounds for MIR4706 Gene

No Compound Related Data Available

Transcripts for MIR4706 Gene

mRNA/cDNA for MIR4706 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

miRNA Products

Clone Products

  • Applied Biological Materials Clones for MIR4706
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4706 Gene

No ASD Table

Relevant External Links for MIR4706 Gene

GeneLoc Exon Structure for
MIR4706
ECgene alternative splicing isoforms for
MIR4706

Expression for MIR4706 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR4706 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4706 Gene:

MIR4706
genes like me logo Genes that share expression patterns with MIR4706: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4706 Gene

Orthologs for MIR4706 Gene

Evolution for MIR4706 Gene

ENSEMBL:
Gene Tree for MIR4706 (if available)
TreeFam:
Gene Tree for MIR4706 (if available)

No data available for Orthologs for MIR4706 Gene

Paralogs for MIR4706 Gene

No data available for Paralogs for MIR4706 Gene

Variants for MIR4706 Gene

Sequence variations from dbSNP and Humsavar for MIR4706 Gene

SNP ID Clin Chr 14 pos Sequence Context AA Info Type
rs1000680029 -- 65,043,871(+) GTAGT(A/G)CCAAA intron-variant, upstream-variant-2KB
rs1002351510 -- 65,044,811(+) AACCC(G/T)CAGTG intron-variant, downstream-variant-500B
rs1003811538 -- 65,043,799(+) AGTCC(A/G)GCCTG intron-variant, upstream-variant-2KB
rs1006549388 -- 65,045,165(+) GCTAA(C/T)TCCTG intron-variant, downstream-variant-500B
rs1006580781 -- 65,043,106(+) GTACC(C/G/T)TCCCC intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR4706 Gene

Variant ID Type Subtype PubMed ID
esv2748779 CNV deletion 23290073
nsv832816 CNV gain 17160897

Relevant External Links for MIR4706 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4706

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4706 Gene

Disorders for MIR4706 Gene

Relevant External Links for MIR4706

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR4706

No disorders were found for MIR4706 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4706 Gene

Publications for MIR4706 Gene

  1. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3 60
  2. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H … Rovira C (Cancer research 2011) 3 60
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 60

Products for MIR4706 Gene

Sources for MIR4706 Gene

Content
Loading form....