Aliases for MIR4703 Gene
Subcategory (RNA class) for MIR4703 Gene
miRNA
Quality Score for this RNA gene is
3
External Ids for MIR4703 Gene
- HGNC: 41817
- Entrez Gene: 100616423
- Ensembl: ENSG00000266611
- miRBase: hsa-mir-4703
Previous GeneCards Identifiers for MIR4703 Gene
- GC13U900856
- GC13P052130
Summaries for MIR4703 Gene
-
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
GeneCards Summary for MIR4703 Gene
MIR4703 (MicroRNA 4703) is an RNA Gene, and is affiliated with the miRNA class.
No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4703 Gene
Genomics for MIR4703 Gene
Regulatory Elements for MIR4703 Gene
Enhancers for MIR4703 Gene
| GeneHancer Identifier | Enhancer Score | Enhancer Sources | Gene-Enhancer Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Gene Targets for Enhancer |
|---|---|---|---|---|---|---|---|---|
| GH13G051549 | 1.1 | Ensembl ENCODE | 0.7 | -3.2 | -3197 | 0.4 | HDAC1 ELF3 TBL1XR1 THRB RARA GLIS2 EGR1 FOS ETV6 IKZF2 | WDFY2 MIR4703 SNRPGP11 |
| GH13G051556 | 1 | Ensembl ENCODE | 0.7 | +4.9 | 4898 | 2.8 | ZMYM3 CEBPG FOSL1 ZFHX2 FOS ZNF600 MAFK EGR2 HLF CEBPB | WDFY2 RNY1P6 DHRS12 MIR4703 RNU6-65P |
| GH13G051552 | 0.7 | FANTOM5 | 0.7 | -0.3 | -347 | 0.2 | FOSL1 L3MBTL2 GATA2 NRF1 MAX MYC SPI1 | DHRS12 WDFY2 INTS6 MIR4703 SNRPGP11 |
| GH13G051532 | 1.1 | FANTOM5 Ensembl ENCODE | 0.4 | -18.4 | -18443 | 3.1 | SOX5 SOX13 TEAD4 MAX ZNF766 IKZF1 EED MYC ZNF558 | DHRS12 ENSG00000231856 WDFY2 INTS6 MIR4703 SNRPGP11 |
| GH13G051561 | 1 | Ensembl ENCODE | 0.4 | +9.8 | 9759 | 1.1 | TBL1XR1 RELA ZNF316 EED ETV6 RELB IKZF2 MAFK CREM MTA2 | DHRS12 ENSG00000231856 RNU6-65P MIR4703 |
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around MIR4703 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Location for MIR4703 Gene
- Chromosome:
- 13
- Start:
- 51,552,589 bp from pter
- End:
- 51,552,667 bp from pter
- Size:
- 79 bases
- Orientation:
- Plus strand
Genomic View for MIR4703 Gene
Genes around MIR4703 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 13q14.3 by Ensembl
- 13q14.3 by Entrez Gene
- 13q14.3 by HGNC
MIR4703 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for MIR4703 Gene
Proteins for MIR4703 Gene
Post-translational modifications for MIR4703 Gene
No Post-translational modifications
Antibody Products
- Search GeneTex for Antibodies for MIR4703
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for MIR4703
- Origene Custom Protein Services for MIR4703
- Search GeneTex for Proteins for MIR4703
Assay Products
No data available for DME Specific Peptides for MIR4703 Gene
Domains & Families for MIR4703 Gene
Gene Families for MIR4703 Gene
- HGNC:
Graphical View of Domain Structure for InterPro Entry
No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4703 Gene
Function for MIR4703 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for MIR4703
-
- Search ViGene Biosciences for MIR4703
CRISPR Products
- Browse CRISPR knockouts for MIR4703
Inhibitory RNA Products
- Search ViGene Biosciences for MIR4703
Clone Products
- GenScript: Custom all cDNA clones Services for MIR4703
- VectorBuilder custom plasmid, inducible vectors for MIR4703
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for MIR4703
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
- Search ViGene Biosciences for MIR4703
Flow Cytometry Products
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4703 Gene
Localization for MIR4703 Gene
No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4703 Gene
Transcripts for MIR4703 Gene
mRNA/cDNA for MIR4703 Gene
- (1) Ensembl transcripts including schematic representations, and UCSC links where relevant :
CRISPR Products
- Browse CRISPR knockouts for MIR4703
Inhibitory RNA Products
- Search ViGene Biosciences for MIR4703
Clone Products
- GenScript: Custom all cDNA clones Services for MIR4703
- VectorBuilder custom plasmid, inducible vectors for MIR4703
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for MIR4703
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
Expression for MIR4703 Gene
NURSA nuclear receptor signaling pathways regulating expression of MIR4703 Gene:
MIR4703
No Expression Related Data Available
Primer Products
No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4703 Gene
Orthologs for MIR4703 Gene
No data available for Orthologs for MIR4703 Gene
Paralogs for MIR4703 Gene
No data available for Paralogs for MIR4703 Gene
Variants for MIR4703 Gene
| SNP ID | Clin | Chr 13 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000941159 | -- | 51,550,875(+) | TGAAC(G/T)CATTA | upstream-variant-2KB | |
| rs1001339742 | -- | 51,552,152(+) | TTGCT(A/G)ACAAC | upstream-variant-2KB | |
| rs1001613879 | -- | 51,551,622(+) | AGCTT(C/T)CTTAT | upstream-variant-2KB | |
| rs1001643580 | -- | 51,551,799(+) | AAATA(C/T)GATTG | upstream-variant-2KB | |
| rs1002797878 | -- | 51,551,368(+) | TATAA(A/C)AAGAG | upstream-variant-2KB |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv3892343 | CNV | gain | 25118596 |
Relevant External Links for MIR4703 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- MIR4703
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4703 Gene
Disorders for MIR4703 Gene
Relevant External Links for MIR4703
- Atlas of Genetics and Cytogenetics in Oncology and Haematology:
- MIR4703
No disorders were found for MIR4703 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4703 Gene
Publications for MIR4703 Gene
- Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H. … Rovira C. (Cancer Res. 2011) 3 64
- miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64
Products for MIR4703 Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Browse OriGene Antibodies
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for MIR4703
- Origene Custom Protein Services for MIR4703
- Browse OriGene Inhibitory RNA Products For MIR4703
- Browse OriGene qPCR primer pairs and template standards
- Browse CRISPR knockouts for MIR4703
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For MIR4703
- GenScript: Custom all cDNA clones Services for MIR4703
- GenScript Custom Purified and Recombinant Proteins Services for MIR4703
- GenScript Custom Assay Services for MIR4703
- GenScript Custom overexpressing Cell Line Services for MIR4703
- Browse GenScript CRISPR for MIR4703
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
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- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
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- Browse Sino Biological cDNA Clones
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- Sino Biological Antibodies
- Sino Biological ELISA Kits and Pair Sets
- Sino Biological Cell Lysates
- Sino Biological qPCR Primers
- Sino Biological CRO Services for Proteins, Antibodies and Genes
- Sino Biological Transfection Reagents
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Cyagen custom Knockout/knockin (KOKI) mouse models for MIR4703
- VectorBuilder custom plasmid, inducible vectors for MIR4703
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for MIR4703
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for MIR4703 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
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- (122) diseasecard
- (123) NIH Rare Diseases
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- (125) UMLS
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- (128) Genetics Home Reference
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- (130) MedlinePlus
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- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer