Aliases for MIR4703 Gene
Subcategory (RNA class) for MIR4703 Gene
miRNA
Quality Score for this RNA gene is
3
External Ids for MIR4703 Gene
- HGNC: 41817
- Entrez Gene: 100616423
- Ensembl: ENSG00000266611
- miRBase: hsa-mir-4703
Previous GeneCards Identifiers for MIR4703 Gene
- GC13U900856
- GC13P052130
Summaries for MIR4703 Gene
-
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
GeneCards Summary for MIR4703 Gene
MIR4703 (MicroRNA 4703) is an RNA Gene, and is affiliated with the miRNA class.
Additional gene information for MIR4703 Gene
No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4703 Gene
Genomics for MIR4703 Gene
GeneHancer (GH) Regulatory Elements for MIR4703 Gene
Promoters and enhancers for MIR4703 Gene
| GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
|---|---|---|---|---|---|---|---|---|---|---|
| GH13I051552 | Enhancer | 0.7 | FANTOM5 | 550.8 | -0.3 | -347 | 0.2 | L3MBTL2 TEAD4 NRF1 MAX MITF FOSL1 ZNF184 PHF20 VEZF1 MYC | MIR4703 DHRS12 WDFY2 INTS6 SNRPGP11 INTS6-AS1 | |
| GH13I051549 | Enhancer | 1.1 | Ensembl ENCODE | 0.8 | -3.2 | -3196 | 0.4 | HDAC1 ELF3 BATF IRF4 THRB RARA GLIS2 EGR1 ETV6 FOS | WDFY2 MIR4703 SNRPGP11 INTS6-AS1 | |
| GH13I051556 | Enhancer | 0.9 | Ensembl ENCODE | 0.8 | +4.9 | 4898 | 2.8 | ZNF449 ZMYM3 CEBPG FOSL1 ZFHX2 FOSL2 ZNF600 FOS EGR2 HLF | RNY1P6 WDFY2 DHRS12 MIR4703 RNU6-65P | |
| GH13I051532 | Enhancer | 1 | FANTOM5 Ensembl ENCODE | 0.4 | -18.4 | -18443 | 3.1 | SOX5 SOX13 MAX ZNF766 POLR2A RUNX3 MYC ZNF558 | DHRS12 ENSG00000231856 WDFY2 INTS6 MIR4703 SNRPGP11 INTS6-AS1 | |
| GH13I051561 | Enhancer | 0.9 | Ensembl ENCODE | 0.4 | +9.8 | 9759 | 1.1 | BATF IRF4 RELA NFATC1 ATF7 ETV6 BCLAF1 IKZF2 RUNX3 ZNF687 | DHRS12 ENSG00000231856 RNU6-65P MIR4703 |
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around MIR4703 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Locations for MIR4703 Gene
Genomic Locations for MIR4703 Gene
- chr13:51,552,589-51,552,667
- (GRCh38/hg38)
- Size:
- 79 bases
- Orientation:
- Plus strand
- chr13:52,126,725-52,126,803
- (GRCh37/hg19)
Genomic View for MIR4703 Gene
Genes around MIR4703 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 13q14.3 by Ensembl
- 13q14.3 by Entrez Gene
- 13q14.3 by HGNC
MIR4703 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for MIR4703 Gene
Proteins for MIR4703 Gene
Post-translational modifications for MIR4703 Gene
No Post-translational modifications
Antibody Products
- Search GeneTex for Antibodies for MIR4703
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for MIR4703
- Origene Custom Protein Services for MIR4703
- Search GeneTex for Proteins for MIR4703
No data available for DME Specific Peptides for MIR4703 Gene
Domains & Families for MIR4703 Gene
Gene Families for MIR4703 Gene
- HGNC:
Graphical View of Domain Structure for InterPro Entry
No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4703 Gene
Function for MIR4703 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for MIR4703
-
- Search ViGene Biosciences for MIR4703
CRISPR Products
- Browse CRISPR knockouts for MIR4703
- Applied Biological Materials CRISPR for MIR4703
-
Vectors and viruses for KO, Activation, Repression, and more
Inhibitory RNA Products
- Search ViGene Biosciences for MIR4703
Clone Products
- GenScript: Custom all cDNA clones Services for MIR4703
- VectorBuilder custom plasmid, inducible vectors for MIR4703
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for MIR4703
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for MIR4703
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4703 Gene
Localization for MIR4703 Gene
No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4703 Gene
Transcripts for MIR4703 Gene
mRNA/cDNA for MIR4703 Gene
- (1) Ensembl transcripts including schematic representations, and UCSC links where relevant :
CRISPR Products
- Browse CRISPR knockouts for MIR4703
- Applied Biological Materials CRISPR for MIR4703
-
Vectors and viruses for KO, Activation, Repression, and more
Inhibitory RNA Products
- Search ViGene Biosciences for MIR4703
Clone Products
- GenScript: Custom all cDNA clones Services for MIR4703
- VectorBuilder custom plasmid, inducible vectors for MIR4703
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for MIR4703
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for MIR4703
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Expression for MIR4703 Gene
NURSA nuclear receptor signaling pathways regulating expression of MIR4703 Gene:
MIR4703
No Expression Related Data Available
Primer Products
No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4703 Gene
Orthologs for MIR4703 Gene
No data available for Orthologs for MIR4703 Gene
Paralogs for MIR4703 Gene
No data available for Paralogs for MIR4703 Gene
Variants for MIR4703 Gene
| SNP ID | Clin | Chr 13 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000941159 | -- | 51,550,875(+) | T/G | upstream_transcript_variant | |
| rs1001339742 | -- | 51,552,152(+) | G/A | upstream_transcript_variant | |
| rs1001613879 | -- | 51,551,622(+) | C/T | upstream_transcript_variant | |
| rs1001643580 | -- | 51,551,799(+) | C/T | upstream_transcript_variant | |
| rs1002797878 | -- | 51,551,368(+) | A/C | upstream_transcript_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv3892343 | CNV | gain | 25118596 |
Additional Variant Information for MIR4703 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- MIR4703
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4703 Gene
Disorders for MIR4703 Gene
Additional Disease Information for MIR4703
No disorders were found for MIR4703 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4703 Gene
Publications for MIR4703 Gene
- Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H … Rovira C (Cancer research 2011) 3 58
- miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58
Products for MIR4703 Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
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- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Browse OriGene Antibodies
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for MIR4703
- Origene Custom Protein Services for MIR4703
- Browse OriGene Inhibitory RNA Products For MIR4703
- Browse OriGene qPCR primer pairs and template standards
- Browse CRISPR knockouts for MIR4703
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For MIR4703
- GenScript: Custom all cDNA clones Services for MIR4703
- GenScript Custom Purified and Recombinant Proteins Services for MIR4703
- GenScript Custom Assay Services for MIR4703
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- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
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- Browse Sino Biological cDNA Clones
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- Sino Biological Transfection Reagent
- Sino Biological Anti-His Tag Antibody
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Browse Antibodies at Cloud-Clone Corp.
- Browse Proteins at Cloud-Clone Corp.
- Browse Assay Kits at Cloud-Clone Corp.
- Browse Knockouts at Cloud-Clone Corp.
- Browse Knockins at Cloud-Clone Corp.
- Cloud-Clone Corp. disease models service
- Browse cDNA clones at Cloud-Clone Corp.
- Browse primers at Cloud-Clone Corp.
- Cloud-Clone Corp. primary cells service
- Cyagen custom Knockout/knockin (KOKI) mouse models for MIR4703
- VectorBuilder custom plasmid, inducible vectors for MIR4703
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for MIR4703
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Search GeneTex for Antibodies for MIR4703
- Search GeneTex for Proteins for MIR4703
Sources for MIR4703 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew