Free for academic non-profit institutions. Other users need a Commercial license

Aliases for MIR4701 Gene

Subcategory (RNA class) for MIR4701 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4701 Gene

  • MicroRNA 4701 2 3 5
  • Hsa-Mir-4701 3

External Ids for MIR4701 Gene

Previous GeneCards Identifiers for MIR4701 Gene

  • GC12U901594
  • GC12M049173
  • GC12M049179

Summaries for MIR4701 Gene

Entrez Gene Summary for MIR4701 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4701 Gene

MIR4701 (MicroRNA 4701) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4701 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4701 Gene

Genomics for MIR4701 Gene

Regulatory Elements for MIR4701 Gene

Enhancers for MIR4701 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH12H048779 1.2 Ensembl ENCODE dbSUPER 0.4 -8.7 -8740 2 BCOR NFIB JUN ZIC2 FOSL1 ADNP SCRT2 FOS ZNF639 SMARCE1 CACNB3 ADCY6 MIR4701
GH12H048786 1.2 ENCODE dbSUPER 0.4 -16.6 -16588 4 PKNOX1 ZNF133 ARID4B SIN3A GLI4 BRCA1 ZNF2 ZNF121 GLIS2 SP3 LOC390314 DDX23 KMT2D CCNT1 HDAC7 KANSL2 CACNB3 ADCY6 MIR4701
GH12H048768 0.6 ENCODE dbSUPER 0.7 +3.7 3685 0 ZIC2 ADCY6 CACNB3 KANSL2 GC12P048770 MIR4701
GH12H048778 0.7 ENCODE dbSUPER 0.4 -5.6 -5626 0 RFX1 MAX MIR4701 ADCY6
GH12H048777 0.4 dbSUPER 0.4 -6.2 -6216 0 RFX1 MAX MIR4701 ADCY6
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR4701 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR4701 Gene

Chromosome:
12
Start:
48,771,975 bp from pter
End:
48,772,037 bp from pter
Size:
63 bases
Orientation:
Minus strand

Genomic View for MIR4701 Gene

Genes around MIR4701 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4701 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4701 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4701 Gene

Proteins for MIR4701 Gene

Post-translational modifications for MIR4701 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4701 Gene

Domains & Families for MIR4701 Gene

Gene Families for MIR4701 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4701: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4701 Gene

Function for MIR4701 Gene

Animal Model Products

CRISPR Products

miRNA Products

Clone Products

  • Applied Biological Materials Clones for MIR4701
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4701 Gene

Localization for MIR4701 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4701 Gene

Pathways & Interactions for MIR4701 Gene

SuperPathways for MIR4701 Gene

No Data Available

Interacting Proteins for MIR4701 Gene

Gene Ontology (GO) - Biological Process for MIR4701 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4701 Gene

Drugs & Compounds for MIR4701 Gene

No Compound Related Data Available

Transcripts for MIR4701 Gene

mRNA/cDNA for MIR4701 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

miRNA Products

Clone Products

  • Applied Biological Materials Clones for MIR4701
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4701 Gene

No ASD Table

Relevant External Links for MIR4701 Gene

GeneLoc Exon Structure for
MIR4701
ECgene alternative splicing isoforms for
MIR4701

Expression for MIR4701 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR4701 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4701 Gene:

MIR4701
genes like me logo Genes that share expression patterns with MIR4701: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4701 Gene

Orthologs for MIR4701 Gene

Evolution for MIR4701 Gene

ENSEMBL:
Gene Tree for MIR4701 (if available)
TreeFam:
Gene Tree for MIR4701 (if available)

No data available for Orthologs for MIR4701 Gene

Paralogs for MIR4701 Gene

No data available for Paralogs for MIR4701 Gene

Variants for MIR4701 Gene

Sequence variations from dbSNP and Humsavar for MIR4701 Gene

SNP ID Clin Chr 12 pos Sequence Context AA Info Type
rs879253864 Likely pathogenic 48,771,786(-) GTTCT(A/G)TGTGG nc-transcript-variant, downstream-variant-500B, reference, missense
rs1000937427 -- 48,771,860(+) TCATC(A/G)TTGCG nc-transcript-variant, downstream-variant-500B, reference, synonymous-codon
rs1000968505 -- 48,772,116(+) AAGGG(G/T)TAAAG intron-variant, upstream-variant-2KB
rs1001969055 -- 48,773,811(+) GGCCC(C/T)TGGTT intron-variant, upstream-variant-2KB
rs1004382120 -- 48,772,991(+) GCTAA(C/T)GAGCA intron-variant, upstream-variant-2KB

Relevant External Links for MIR4701 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4701

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR4701 Gene

Disorders for MIR4701 Gene

Relevant External Links for MIR4701

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR4701

No disorders were found for MIR4701 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4701 Gene

Publications for MIR4701 Gene

  1. Alpha-2, 3-sialyltransferases regulate the multidrug resistance of chronic myeloid leukemia through miR-4701-5p targeting ST3GAL1. (PMID: 27088512) Li Y … Jia L (Laboratory investigation; a journal of technical methods and pathology 2016) 3 60
  2. Clozapine-induced agranulocytosis is associated with rare HLA-DQB1 and HLA-B alleles. (PMID: 25187353) Goldstein JI … Sullivan PF (Nature communications 2014) 3 60
  3. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H … Rovira C (Cancer research 2011) 3 60
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 60

Products for MIR4701 Gene

Sources for MIR4701 Gene

Content
Loading form....