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Aliases for MIR4701 Gene

Subcategory (RNA class) for MIR4701 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4701 Gene

  • MicroRNA 4701 2 3 5
  • Hsa-Mir-4701 3

External Ids for MIR4701 Gene

Previous GeneCards Identifiers for MIR4701 Gene

  • GC12U901594
  • GC12M049173
  • GC12M049179

Summaries for MIR4701 Gene

Entrez Gene Summary for MIR4701 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4701 Gene

MIR4701 (MicroRNA 4701) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4701 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4701 Gene

Genomics for MIR4701 Gene

GeneHancer (GH) Regulatory Elements for MIR4701 Gene

Promoters and enhancers for MIR4701 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH12I048786 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE dbSUPER 0.4 -16.6 -16587 4.1 PKNOX1 ZNF133 ARID4B SIN3A GLI4 ZNF2 BRCA1 ZNF121 GLIS2 ZNF213 LOC100506125 ADCY6 LOC390314 DDX23 KMT2D CCNT1 HDAC7 KANSL2 CACNB3 MIR4701
GH12I048779 Enhancer 1.1 Ensembl ENCODE dbSUPER 0.4 -8.7 -8740 2.8 BCOR NFATC3 NFIB JUN ZIC2 FOSL1 ZNF335 ADNP SCRT2 VEZF1 CACNB3 ADCY6 MIR4701
GH12I048768 Enhancer 0.5 ENCODE dbSUPER 0.8 +3.7 3684 0.2 ZIC2 GC12P048770 ADCY6 CACNB3 KANSL2 MIR4701
GH12I048778 Enhancer 0.6 ENCODE dbSUPER 0.4 -5.6 -5626 0.2 RFX1 MAX MIR4701 ADCY6
GH12I048777 Enhancer 0.4 dbSUPER 0.4 -6.2 -6216 0.9 RFX1 MAX MIR4701 ADCY6
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR4701 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR4701 Gene

Genomic Locations for MIR4701 Gene
chr12:48,771,975-48,772,037
(GRCh38/hg38)
Size:
63 bases
Orientation:
Minus strand
chr12:49,165,746-49,165,827
(GRCh37/hg19)

Genomic View for MIR4701 Gene

Genes around MIR4701 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4701 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4701 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4701 Gene

Proteins for MIR4701 Gene

Post-translational modifications for MIR4701 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4701 Gene

Domains & Families for MIR4701 Gene

Gene Families for MIR4701 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4701: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4701 Gene

Function for MIR4701 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4701 Gene

Localization for MIR4701 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4701 Gene

Pathways & Interactions for MIR4701 Gene

SuperPathways for MIR4701 Gene

No Data Available

Interacting Proteins for MIR4701 Gene

Gene Ontology (GO) - Biological Process for MIR4701 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4701 Gene

Drugs & Compounds for MIR4701 Gene

No Compound Related Data Available

Transcripts for MIR4701 Gene

mRNA/cDNA for MIR4701 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4701 Gene

No ASD Table

Relevant External Links for MIR4701 Gene

GeneLoc Exon Structure for
MIR4701
ECgene alternative splicing isoforms for
MIR4701

Expression for MIR4701 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR4701 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4701 Gene:

MIR4701
genes like me logo Genes that share expression patterns with MIR4701: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4701 Gene

Orthologs for MIR4701 Gene

Evolution for MIR4701 Gene

ENSEMBL:
Gene Tree for MIR4701 (if available)
TreeFam:
Gene Tree for MIR4701 (if available)

No data available for Orthologs for MIR4701 Gene

Paralogs for MIR4701 Gene

No data available for Paralogs for MIR4701 Gene

Variants for MIR4701 Gene

Sequence variations from dbSNP and Humsavar for MIR4701 Gene

SNP ID Clin Chr 12 pos Variation AA Info Type
rs879253864 likely-pathogenic, Lethal congenital contracture syndrome 8 48,771,786(-) T/C downstream_transcript_variant
rs1000937427 -- 48,771,860(-) A/G downstream_transcript_variant
rs1000968505 -- 48,772,116(-) G/T upstream_transcript_variant
rs1001969055 -- 48,773,811(-) C/T upstream_transcript_variant
rs1004382120 -- 48,772,991(-) T/C upstream_transcript_variant

Additional Variant Information for MIR4701 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4701

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR4701 Gene

Disorders for MIR4701 Gene

Additional Disease Information for MIR4701

No disorders were found for MIR4701 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4701 Gene

Publications for MIR4701 Gene

  1. Alpha-2, 3-sialyltransferases regulate the multidrug resistance of chronic myeloid leukemia through miR-4701-5p targeting ST3GAL1. (PMID: 27088512) Li Y … Jia L (Laboratory investigation; a journal of technical methods and pathology 2016) 3 58
  2. Clozapine-induced agranulocytosis is associated with rare HLA-DQB1 and HLA-B alleles. (PMID: 25187353) Goldstein JI … Sullivan PF (Nature communications 2014) 3 58
  3. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H … Rovira C (Cancer research 2011) 3 58
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR4701 Gene

Sources for MIR4701 Gene

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