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Aliases for MIR4697 Gene

Subcategory (RNA class) for MIR4697 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4697 Gene

  • MicroRNA 4697 2 3 5
  • Hsa-Mir-4697 3

External Ids for MIR4697 Gene

Previous GeneCards Identifiers for MIR4697 Gene

  • GC11U901871
  • GC11M133771

Summaries for MIR4697 Gene

Entrez Gene Summary for MIR4697 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4697 Gene

MIR4697 (MicroRNA 4697) is an RNA Gene, and is affiliated with the miRNA class.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4697 Gene

Genomics for MIR4697 Gene

Regulatory Elements for MIR4697 Gene

Enhancers for MIR4697 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH11G133895 0.4 ENCODE 0.7 +3.2 3221 0.2 RELA IGSF9B SPATA19 MIR4697 LOC283172
GH11G133896 0.4 ENCODE 0.7 +3.4 3421 0.2 TEAD4 RELA IGSF9B SPATA19 MIR4697 LOC283172
GH11G133898 0.4 ENCODE 0.7 0.0 -10 0.2 CTCF NR2F1 MIR4697 PIR56503
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR4697 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR4697 Gene

Chromosome:
11
Start:
133,898,504 bp from pter
End:
133,898,581 bp from pter
Size:
78 bases
Orientation:
Minus strand

Genomic View for MIR4697 Gene

Genes around MIR4697 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4697 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4697 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4697 Gene

Proteins for MIR4697 Gene

Post-translational modifications for MIR4697 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4697 Gene

Domains & Families for MIR4697 Gene

Gene Families for MIR4697 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4697: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4697 Gene

Function for MIR4697 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4697 Gene

Localization for MIR4697 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4697 Gene

Pathways & Interactions for MIR4697 Gene

SuperPathways for MIR4697 Gene

No Data Available

Interacting Proteins for MIR4697 Gene

Gene Ontology (GO) - Biological Process for MIR4697 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4697 Gene

Drugs & Compounds for MIR4697 Gene

No Compound Related Data Available

Transcripts for MIR4697 Gene

mRNA/cDNA for MIR4697 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4697 Gene

No ASD Table

Relevant External Links for MIR4697 Gene

GeneLoc Exon Structure for
MIR4697
ECgene alternative splicing isoforms for
MIR4697

Expression for MIR4697 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR4697 Gene

mRNA differential expression in normal tissues according to GTEx for MIR4697 Gene

This gene is overexpressed in Brain - Cerebellum (x5.9), Brain - Cerebellar Hemisphere (x4.8), and Esophagus - Gastroesophageal Junction (x4.2).

NURSA nuclear receptor signaling pathways regulating expression of MIR4697 Gene:

MIR4697
genes like me logo Genes that share expression patterns with MIR4697: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4697 Gene

Orthologs for MIR4697 Gene

Evolution for MIR4697 Gene

ENSEMBL:
Gene Tree for MIR4697 (if available)
TreeFam:
Gene Tree for MIR4697 (if available)

No data available for Orthologs for MIR4697 Gene

Paralogs for MIR4697 Gene

No data available for Paralogs for MIR4697 Gene

Variants for MIR4697 Gene

Sequence variations from dbSNP and Humsavar for MIR4697 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs1000148936 -- 133,899,044(+) CACAT(C/G)TCCCT nc-transcript-variant, upstream-variant-2KB
rs1000368236 -- 133,898,877(+) TTTCA(A/G)ACCGC nc-transcript-variant, upstream-variant-2KB
rs1000704409 -- 133,900,154(+) TCTCA(C/T)GCTGA nc-transcript-variant, upstream-variant-2KB
rs1001591269 -- 133,898,512(+) CCAAG(G/T)GGCAG nc-transcript-variant
rs1001643409 -- 133,898,207(+) GAAGA(A/C)AGAAA nc-transcript-variant, downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for MIR4697 Gene

Variant ID Type Subtype PubMed ID
nsv1051677 CNV gain 25217958
nsv468900 CNV loss 19166990
nsv556595 CNV loss 21841781
nsv952765 CNV deletion 24416366

Relevant External Links for MIR4697 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4697

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4697 Gene

Disorders for MIR4697 Gene

Relevant External Links for MIR4697

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR4697

No disorders were found for MIR4697 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4697 Gene

Publications for MIR4697 Gene

  1. Association of GCH1 and MIR4697, but not SIPA1L2 and VPS13C polymorphisms, with Parkinson's disease in Taiwan. (PMID: 26804608) Chen C.M. … Wu Y.R. (Neurobiol. Aging 2016) 3 64
  2. Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease. (PMID: 25064009) Nalls M.A. … Singleton A.B. (Nat. Genet. 2014) 3 64
  3. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H. … Rovira C. (Cancer Res. 2011) 3 64
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4697 Gene

Sources for MIR4697 Gene

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