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Aliases for MIR4693 Gene

Subcategory (RNA class) for MIR4693 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4693 Gene

  • MicroRNA 4693 2 3 5
  • Hsa-Mir-4693 3

External Ids for MIR4693 Gene

Previous GeneCards Identifiers for MIR4693 Gene

  • GC11U901855
  • GC11P103723

Summaries for MIR4693 Gene

Entrez Gene Summary for MIR4693 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4693 Gene

MIR4693 (MicroRNA 4693) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4693 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4693 Gene

Genomics for MIR4693 Gene

Regulatory Elements for MIR4693 Gene

Enhancers for MIR4693 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH11H103863 0.6 FANTOM5 0.4 +13.8 13800 0 FOSL1 FOS MIR4693 LOC105369464
GH11H103888 0.5 ENCODE 0.3 +38.8 38822 0 JUND ZNF680 JUN CEBPB EP300 ENSG00000255548 LOC105369464 MIR4693
GH11H103851 0.2 ENCODE 0.7 +1.6 1626 0 PDGFD MIR4693 LOC105369464
GH11H103904 0.6 ENCODE 0.2 +54.3 54342 0 TBL1XR1 SIN3A EBF1 BCL11A IKZF1 EED CUX1 ATF7 RUNX3 IKZF2 ENSG00000255548 LOC105369464 MIR4693
GH11H103870 0.3 FANTOM5 0.3 +21.1 21127 0 ENSG00000255548 PDGFD MIR4693 LOC105369464
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR4693 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR4693 Gene

Chromosome:
11
Start:
103,849,906 bp from pter
End:
103,849,980 bp from pter
Size:
75 bases
Orientation:
Plus strand

Genomic View for MIR4693 Gene

Genes around MIR4693 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4693 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4693 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4693 Gene

Proteins for MIR4693 Gene

Post-translational modifications for MIR4693 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4693 Gene

Domains & Families for MIR4693 Gene

Gene Families for MIR4693 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4693: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4693 Gene

Function for MIR4693 Gene

Animal Model Products

CRISPR Products

miRNA Products

Clone Products

  • Applied Biological Materials Clones for MIR4693
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4693 Gene

Localization for MIR4693 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4693 Gene

Pathways & Interactions for MIR4693 Gene

SuperPathways for MIR4693 Gene

No Data Available

Interacting Proteins for MIR4693 Gene

Gene Ontology (GO) - Biological Process for MIR4693 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4693 Gene

Drugs & Compounds for MIR4693 Gene

No Compound Related Data Available

Transcripts for MIR4693 Gene

mRNA/cDNA for MIR4693 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

miRNA Products

Clone Products

  • Applied Biological Materials Clones for MIR4693
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4693 Gene

No ASD Table

Relevant External Links for MIR4693 Gene

GeneLoc Exon Structure for
MIR4693
ECgene alternative splicing isoforms for
MIR4693

Expression for MIR4693 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4693 Gene:

MIR4693
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4693 Gene

Orthologs for MIR4693 Gene

Evolution for MIR4693 Gene

ENSEMBL:
Gene Tree for MIR4693 (if available)
TreeFam:
Gene Tree for MIR4693 (if available)

No data available for Orthologs for MIR4693 Gene

Paralogs for MIR4693 Gene

No data available for Paralogs for MIR4693 Gene

Variants for MIR4693 Gene

Sequence variations from dbSNP and Humsavar for MIR4693 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs1002443448 -- 103,848,044(+) CTACA(C/T)TCCTG nc-transcript-variant, upstream-variant-2KB
rs1002709583 -- 103,848,054(+) GCCAC(A/G)TCGGA nc-transcript-variant, upstream-variant-2KB
rs1002774008 -- 103,849,209(+) ATTTT(C/T)GCTCC intron-variant, upstream-variant-2KB
rs1002906360 -- 103,848,272(+) TCTGA(G/T)TTTTT intron-variant, upstream-variant-2KB
rs1003012618 -- 103,849,083(+) TCACT(G/T)ATATT intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR4693 Gene

Variant ID Type Subtype PubMed ID
esv2750977 CNV gain 17911159

Relevant External Links for MIR4693 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4693

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4693 Gene

Disorders for MIR4693 Gene

Relevant External Links for MIR4693

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR4693

No disorders were found for MIR4693 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4693 Gene

Publications for MIR4693 Gene

  1. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H … Rovira C (Cancer research 2011) 3 60
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 60

Products for MIR4693 Gene

Sources for MIR4693 Gene

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