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Aliases for MIR4688 Gene

Subcategory (RNA class) for MIR4688 Gene


Quality Score for this RNA gene is


Aliases for MIR4688 Gene

  • MicroRNA 4688 2 3 5
  • Hsa-Mir-4688 3
  • Mir-4688 3

External Ids for MIR4688 Gene

Previous GeneCards Identifiers for MIR4688 Gene

  • GC11U901859

Summaries for MIR4688 Gene

Entrez Gene Summary for MIR4688 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4688 Gene

MIR4688 (MicroRNA 4688) is an RNA Gene, and is affiliated with the miRNA class.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4688 Gene

Genomics for MIR4688 Gene

Regulatory Elements for MIR4688 Gene

Enhancers for MIR4688 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH11G046378 1.3 ENCODE dbSUPER 0.7 +4.1 4132 4.6 PKNOX1 FOXA2 AGO1 ZFP64 SIN3A ARID4B ZNF143 ZNF263 SP3 SP5 ATG13 C11orf49 MIR4688 MDK
GH11G046359 1.6 Ensembl ENCODE dbSUPER 0.4 -13.9 -13851 5.4 HDGF FOXA2 PKNOX1 AGO1 SIN3A ARID4B YY1 ZNF766 ZNF143 FOS ZNF408 ATG13 MIR4688 GC11P046351
GH11G046356 1.4 Ensembl ENCODE dbSUPER 0.4 -19.2 -19209 2.3 HDGF CBX3 AGO1 ARID4B ZNF48 ZNF335 GLIS2 EGR1 ZNF143 EGR2 ENSG00000271350 ATG13 C11orf49 GC11P046351 MIR4688
GH11G046367 1.2 ENCODE dbSUPER 0.4 -8.9 -8926 1.3 HDGF ATF1 PKNOX1 AGO1 ARID4B SIN3A ZNF48 ZNF2 GLIS2 ZNF143 MIR4688 GC11P046351
GH11G046369 1.1 ENCODE dbSUPER 0.4 -6.8 -6835 1.0 HDGF RB1 ARID4B RAD21 GLIS2 EGR1 ZNF143 PCBP1 EGR2 SP3 C11orf49 MIR4688 GC11P046351
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR4688 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR4688 Gene

46,376,402 bp from pter
46,376,484 bp from pter
83 bases
Plus strand

Genomic View for MIR4688 Gene

Genes around MIR4688 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4688 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4688 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4688 Gene

Proteins for MIR4688 Gene

Post-translational modifications for MIR4688 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4688 Gene

Domains & Families for MIR4688 Gene

Gene Families for MIR4688 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4688: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4688 Gene

Function for MIR4688 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4688 Gene

Localization for MIR4688 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4688 Gene

Pathways & Interactions for MIR4688 Gene

SuperPathways for MIR4688 Gene

No Data Available

Interacting Proteins for MIR4688 Gene

Gene Ontology (GO) - Biological Process for MIR4688 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR4688 Gene

Drugs & Compounds for MIR4688 Gene

No Compound Related Data Available

Transcripts for MIR4688 Gene

mRNA/cDNA for MIR4688 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4688 Gene

No ASD Table

Relevant External Links for MIR4688 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR4688 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR4688 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4688 Gene:

genes like me logo Genes that share expression patterns with MIR4688: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4688 Gene

Orthologs for MIR4688 Gene

Evolution for MIR4688 Gene

Gene Tree for MIR4688 (if available)
Gene Tree for MIR4688 (if available)

No data available for Orthologs for MIR4688 Gene

Paralogs for MIR4688 Gene

No data available for Paralogs for MIR4688 Gene

Variants for MIR4688 Gene

Sequence variations from dbSNP and Humsavar for MIR4688 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs1000059396 -- 46,375,070(+) ATGGT(G/T)CCTGG intron-variant, upstream-variant-2KB
rs1003201116 -- 46,375,131(+) ACGGC(A/G)GCCTA intron-variant, upstream-variant-2KB
rs1003276901 -- 46,376,247(+) CCTCT(A/G)TGCTG intron-variant, upstream-variant-2KB
rs1004832877 -- 46,376,810(+) GGAGG(C/G)CCTGG intron-variant, downstream-variant-500B
rs1005060467 -- 46,375,978(+) GGCAG(G/T)GTGGC intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR4688 Gene

Variant ID Type Subtype PubMed ID
esv3626183 CNV gain 21293372
esv3626185 CNV loss 21293372
nsv554201 CNV loss 21841781
nsv554202 CNV loss 21841781
nsv825867 CNV gain 20364138
nsv951610 CNV deletion 24416366

Relevant External Links for MIR4688 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4688 Gene

Disorders for MIR4688 Gene

Relevant External Links for MIR4688

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR4688 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4688 Gene

Publications for MIR4688 Gene

  1. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A. … Griffiths-Jones S. (Nucleic Acids Res. 2011) 3 64
  2. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H. … Rovira C. (Cancer Res. 2011) 3 64
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4688 Gene

Sources for MIR4688 Gene

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