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Aliases for MIR4684 Gene

Subcategory (RNA class) for MIR4684 Gene


Quality Score for this RNA gene is


Aliases for MIR4684 Gene

  • MicroRNA 4684 2 3 5
  • Hsa-Mir-4684 3

External Ids for MIR4684 Gene

Previous GeneCards Identifiers for MIR4684 Gene

  • GC01U903289
  • GC01P023049

Summaries for MIR4684 Gene

Entrez Gene Summary for MIR4684 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4684 Gene

MIR4684 (MicroRNA 4684) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4684 Gene

Genomics for MIR4684 Gene

Regulatory Elements for MIR4684 Gene

Enhancers for MIR4684 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01F022716 0.6 Ensembl 0.8 -2.3 -2317 1.2 NRF1 ZMYM3 FEZF1 ZIC2 GATA3 GLIS1 NFE2 ZNF423 SPI1 EPHB2 MIR4684
GH01F022711 0.6 ENCODE 0.4 -7.0 -6976 1.2 ATF1 TBL1XR1 FEZF1 RAD21 ZNF121 GLIS2 ZNF366 EGR1 ETV6 FOS ENSG00000225952 KDM1A EPHB2 MIR4684
GH01F022737 1 Ensembl ENCODE 0.3 +19.9 19894 3.2 HDAC1 KLF1 PKNOX1 ESRRA JUN ZFHX2 SCRT2 FOS ZSCAN29 NFE2 ENSG00000225952 EPHB2 LINC00339 GC01P022751 MIR4684
GH01F022735 0.4 Ensembl 0.3 +16.6 16584 2.2 ZNF121 GLIS2 ESRRA ATF3 GLIS1 BHLHE40 SCRT2 FOS ZIC2 ATF2 ENSG00000225952 EPHB2 MIR4684 GC01P022751
GH01F022745 0.8 Ensembl ENCODE 0.3 +27.5 27473 2.8 BCOR JUN ZMYM3 SIN3A ZIC2 RAD21 YY1 GLIS2 HNF4G FOS EPHB2 GC01P022751 MIR4684
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around MIR4684 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR4684 Gene

22,719,517 bp from pter
22,719,598 bp from pter
82 bases
Plus strand

Genomic View for MIR4684 Gene

Genes around MIR4684 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4684 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4684 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4684 Gene

Proteins for MIR4684 Gene

Post-translational modifications for MIR4684 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4684 Gene

Domains & Families for MIR4684 Gene

Gene Families for MIR4684 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4684: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4684 Gene

Function for MIR4684 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4684 Gene

Localization for MIR4684 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4684 Gene

Pathways & Interactions for MIR4684 Gene

SuperPathways for MIR4684 Gene

No Data Available

Interacting Proteins for MIR4684 Gene

Gene Ontology (GO) - Biological Process for MIR4684 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR4684 Gene

Transcripts for MIR4684 Gene

mRNA/cDNA for MIR4684 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4684 Gene

No ASD Table

Relevant External Links for MIR4684 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR4684 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4684 Gene:

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR4684 Gene

Orthologs for MIR4684 Gene

Evolution for MIR4684 Gene

Gene Tree for MIR4684 (if available)
Gene Tree for MIR4684 (if available)

No data available for Orthologs for MIR4684 Gene

Paralogs for MIR4684 Gene

No data available for Paralogs for MIR4684 Gene

Variants for MIR4684 Gene

Sequence variations from dbSNP and Humsavar for MIR4684 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs10799759 -- 22,718,887(+) ACTCC(A/G)GAGCT intron-variant, upstream-variant-2KB
rs10917280 -- 22,717,688(+) TTATT(A/G)GTTTC intron-variant, upstream-variant-2KB
rs111984291 -- 22,719,752(+) AGCTC(C/T)AGGAT intron-variant, downstream-variant-500B
rs114185788 -- 22,719,254(+) CCACT(C/T)TAGAG intron-variant, upstream-variant-2KB
rs114834553 -- 22,717,680(+) TCCAT(G/T)CTTTA intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR4684 Gene

Variant ID Type Subtype PubMed ID
esv34161 CNV loss 18971310

Relevant External Links for MIR4684 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4684 Gene

Disorders for MIR4684 Gene

Relevant External Links for MIR4684

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR4684 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4684 Gene

Publications for MIR4684 Gene

  1. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H. … Rovira C. (Cancer Res. 2011) 3 64
  2. Enhancing miRNA annotation confidence in miRBase by continuous cross dataset analysis. (PMID: 21558790) Hansen T.B. … Bramsen J.B. (RNA Biol 2011) 3 64
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4684 Gene

Sources for MIR4684 Gene

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