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Aliases for MIR4678 Gene

Subcategory (RNA class) for MIR4678 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4678 Gene

  • MicroRNA 4678 2 3 5
  • Hsa-Mir-4678 3

External Ids for MIR4678 Gene

Previous GeneCards Identifiers for MIR4678 Gene

  • GC10U901541
  • GC10P089266

Summaries for MIR4678 Gene

Entrez Gene Summary for MIR4678 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4678 Gene

MIR4678 (MicroRNA 4678) is an RNA Gene, and is affiliated with the miRNA class.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4678 Gene

Genomics for MIR4678 Gene

Regulatory Elements for MIR4678 Gene

Enhancers for MIR4678 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH10G087503 1.1 ENCODE 0.7 +1.9 1915 5.4 MLX WRNIP1 ARID4B SIN3A DMAP1 ZNF2 ZBTB7B ZNF416 ZNF143 FOS PAPSS2 MIR4678 GC10P087578
GH10G087545 1.1 Ensembl ENCODE 0.3 +43.3 43288 2.9 PKNOX1 FEZF1 RAD21 TCF12 CEBPB REST ZEB2 NR2F2 MEF2D ZFP69B PAPSS2 ENSG00000196566 MINPP1 GC10P087578 MIR4678
GH10G087533 0.9 Ensembl ENCODE 0.3 +29.9 29921 0.4 CTCF ZNF654 ZNF362 TRIM22 ZNF384 RAD21 RFX5 YY1 FOXA1 JUND MIR4678 GC10P087578
GH10G087523 0.6 ENCODE 0.3 +20.3 20317 1.0 ELF3 RAD21 YY1 ZNF335 MEF2D JUND GATA2 PRDM1 ZBTB17 MIR4678 GC10P087578
GH10G087531 0.5 ENCODE 0.3 +28.5 28467 0.7 NFIC GATA2 ZNF585B BCL6B NR2F2 MIR4678 GC10P087578
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR4678 on UCSC Golden Path with GeneCards custom track

Promoters for MIR4678 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000031074 1419 2201 MLX WRNIP1 ARID4B SIN3A DMAP1 ZNF2 ZBTB7B ZNF416 ZNF143 DEK

Genomic Location for MIR4678 Gene

Chromosome:
10
Start:
87,503,881 bp from pter
End:
87,503,954 bp from pter
Size:
74 bases
Orientation:
Plus strand

Genomic View for MIR4678 Gene

Genes around MIR4678 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4678 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4678 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4678 Gene

Proteins for MIR4678 Gene

Post-translational modifications for MIR4678 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4678 Gene

Domains & Families for MIR4678 Gene

Gene Families for MIR4678 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4678: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4678 Gene

Function for MIR4678 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4678 Gene

Localization for MIR4678 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4678 Gene

Pathways & Interactions for MIR4678 Gene

SuperPathways for MIR4678 Gene

No Data Available

Interacting Proteins for MIR4678 Gene

Gene Ontology (GO) - Biological Process for MIR4678 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4678 Gene

Drugs & Compounds for MIR4678 Gene

No Compound Related Data Available

Transcripts for MIR4678 Gene

mRNA/cDNA for MIR4678 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4678 Gene

No ASD Table

Relevant External Links for MIR4678 Gene

GeneLoc Exon Structure for
MIR4678
ECgene alternative splicing isoforms for
MIR4678

Expression for MIR4678 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4678 Gene:

MIR4678
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4678 Gene

Orthologs for MIR4678 Gene

Evolution for MIR4678 Gene

ENSEMBL:
Gene Tree for MIR4678 (if available)
TreeFam:
Gene Tree for MIR4678 (if available)

No data available for Orthologs for MIR4678 Gene

Paralogs for MIR4678 Gene

No data available for Paralogs for MIR4678 Gene

Variants for MIR4678 Gene

Sequence variations from dbSNP and Humsavar for MIR4678 Gene

SNP ID Clin Chr 10 pos Sequence Context AA Info Type
rs1001404820 -- 87,503,908(+) GACTT(A/G)TGATT nc-transcript-variant, upstream-variant-2KB, utr-variant-5-prime
rs1001690837 -- 87,502,820(+) TATCA(C/T)TTATA upstream-variant-2KB, utr-variant-5-prime
rs1002023068 -- 87,504,312(+) CTCAA(A/G)TGGAA downstream-variant-500B, upstream-variant-2KB, utr-variant-5-prime
rs1003481250 -- 87,502,141(+) TGGAA(A/G)CTGAG upstream-variant-2KB
rs1004021756 -- 87,503,812(+) TAAAT(A/C)TGGAT upstream-variant-2KB, utr-variant-5-prime

Structural Variations from Database of Genomic Variants (DGV) for MIR4678 Gene

Variant ID Type Subtype PubMed ID
esv26704 CNV gain+loss 19812545
esv2759774 CNV gain+loss 17122850
esv3891880 CNV gain 25118596
nsv428236 CNV loss 18775914
nsv510993 OTHER complex 20534489
nsv551825 CNV gain 21841781

Relevant External Links for MIR4678 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4678

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4678 Gene

Disorders for MIR4678 Gene

Relevant External Links for MIR4678

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR4678

No disorders were found for MIR4678 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4678 Gene

Publications for MIR4678 Gene

  1. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H. … Rovira C. (Cancer Res. 2011) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4678 Gene

Sources for MIR4678 Gene

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