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Aliases for MIR4678 Gene

Subcategory (RNA class) for MIR4678 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4678 Gene

  • MicroRNA 4678 2 3 5
  • Hsa-Mir-4678 3

External Ids for MIR4678 Gene

Previous GeneCards Identifiers for MIR4678 Gene

  • GC10U901541
  • GC10P089266

Summaries for MIR4678 Gene

Entrez Gene Summary for MIR4678 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4678 Gene

MIR4678 (MicroRNA 4678) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4678 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4678 Gene

Genomics for MIR4678 Gene

GeneHancer (GH) Regulatory Elements for MIR4678 Gene

Promoters and enhancers for MIR4678 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH10I087503 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 550.8 +1.9 1914 5.4 MLX ARID4B SIN3A DMAP1 ZNF2 ZBTB7B E2F8 ZNF416 ZNF143 DEK MINPP1 MIR4678 PAPSS2 GC10P087578
GH10I087545 Enhancer 1 Ensembl ENCODE 0.3 +43.3 43287 2.9 PKNOX1 FEZF1 RAD21 TCF12 RUNX3 RXRA CEBPB REST ZEB2 NR2F2 PAPSS2 ENSG00000196566 MINPP1 GC10P087578 MIR4678
GH10I087533 Enhancer 0.8 Ensembl ENCODE 0.3 +29.9 29920 0.4 CTCF ZNF654 ZNF362 TRIM22 ZNF384 RAD21 RFX5 YY1 SCRT2 ZNF143 MIR4678 MINPP1 GC10P087578
GH10I087531 Enhancer 0.5 ENCODE 0.3 +28.5 28467 0.7 NFIC ZNF585B BCL6B NR2F2 ENSG00000272631 MINPP1 MIR4678 GC10P087578
GH10I087541 Enhancer 0.5 ENCODE 0.3 +37.4 37418 0.1 MAFG NFE2 FOSL2 NFE2L2 MINPP1 GC10P087578 MIR4678
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR4678 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR4678 Gene

Genomic Locations for MIR4678 Gene
chr10:87,503,881-87,503,954
(GRCh38/hg38)
Size:
74 bases
Orientation:
Plus strand
chr10:89,263,638-89,263,711
(GRCh37/hg19)

Genomic View for MIR4678 Gene

Genes around MIR4678 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4678 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4678 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4678 Gene

Proteins for MIR4678 Gene

Post-translational modifications for MIR4678 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4678 Gene

Domains & Families for MIR4678 Gene

Gene Families for MIR4678 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4678: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4678 Gene

Function for MIR4678 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4678 Gene

Localization for MIR4678 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4678 Gene

Pathways & Interactions for MIR4678 Gene

SuperPathways for MIR4678 Gene

No Data Available

Interacting Proteins for MIR4678 Gene

Gene Ontology (GO) - Biological Process for MIR4678 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4678 Gene

Drugs & Compounds for MIR4678 Gene

No Compound Related Data Available

Transcripts for MIR4678 Gene

mRNA/cDNA for MIR4678 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4678 Gene

No ASD Table

Relevant External Links for MIR4678 Gene

GeneLoc Exon Structure for
MIR4678
ECgene alternative splicing isoforms for
MIR4678

Expression for MIR4678 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4678 Gene:

MIR4678
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4678 Gene

Orthologs for MIR4678 Gene

Evolution for MIR4678 Gene

ENSEMBL:
Gene Tree for MIR4678 (if available)
TreeFam:
Gene Tree for MIR4678 (if available)

No data available for Orthologs for MIR4678 Gene

Paralogs for MIR4678 Gene

No data available for Paralogs for MIR4678 Gene

Variants for MIR4678 Gene

Sequence variations from dbSNP and Humsavar for MIR4678 Gene

SNP ID Clin Chr 10 pos Variation AA Info Type
rs1001404820 -- 87,503,908(+) A/G non_coding_transcript_variant
rs1001690837 -- 87,502,820(+) T/C upstream_transcript_variant
rs1002023068 -- 87,504,312(+) A/G downstream_transcript_variant
rs1003481250 -- 87,502,141(+) A/G upstream_transcript_variant
rs1004021756 -- 87,503,812(+) C/A upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR4678 Gene

Variant ID Type Subtype PubMed ID
esv26704 CNV gain+loss 19812545
esv2759774 CNV gain+loss 17122850
esv3891880 CNV gain 25118596
nsv428236 CNV loss 18775914
nsv510993 OTHER complex 20534489
nsv551825 CNV gain 21841781

Additional Variant Information for MIR4678 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4678

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4678 Gene

Disorders for MIR4678 Gene

Additional Disease Information for MIR4678

No disorders were found for MIR4678 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4678 Gene

Publications for MIR4678 Gene

  1. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H … Rovira C (Cancer research 2011) 3 58
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR4678 Gene

Sources for MIR4678 Gene

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