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Aliases for MIR4677 Gene

Subcategory (RNA class) for MIR4677 Gene


Quality Score for this RNA gene is


Aliases for MIR4677 Gene

  • MicroRNA 4677 2 3 5
  • Hsa-Mir-4677 3
  • Mir-4677 3

External Ids for MIR4677 Gene

Previous GeneCards Identifiers for MIR4677 Gene

  • GC01U903278
  • GC01P243512

Summaries for MIR4677 Gene

Entrez Gene Summary for MIR4677 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4677 Gene

MIR4677 (MicroRNA 4677) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4677 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4677 Gene

Genomics for MIR4677 Gene

Regulatory Elements for MIR4677 Gene

Enhancers for MIR4677 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01H243325 0.7 ENCODE 0.3 -20.7 -20653 0.1 CTCF ZNF654 CEBPB REST ZNF501 CEBPG ZNF2 RAD21 ZNF592 RFX5 PIR31594 MIR4677
GH01H243354 0.5 Ensembl 0.4 +8.4 8425 0.8 IRF2 RAD21 PRDM1 YY1 MIR4677 GC01P243394
GH01H243323 0.4 FANTOM5 0.3 -22.3 -22302 0.4 FOXA2 CEP170 SDCCAG8 PIR31594 MIR4677
GH01H243390 0.2 ENCODE 0.3 +44.6 44553 1.1 GC01P243394 MIR4677
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR4677 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR4677 Gene

Genomic Locations for MIR4677 Gene
80 bases
Plus strand

Genomic View for MIR4677 Gene

Genes around MIR4677 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4677 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4677 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4677 Gene

Proteins for MIR4677 Gene

Post-translational modifications for MIR4677 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4677 Gene

Domains & Families for MIR4677 Gene

Gene Families for MIR4677 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4677: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4677 Gene

Function for MIR4677 Gene

Phenotypes From GWAS Catalog for MIR4677 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4677 Gene

Localization for MIR4677 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4677 Gene

Pathways & Interactions for MIR4677 Gene

SuperPathways for MIR4677 Gene

No Data Available

Interacting Proteins for MIR4677 Gene

Gene Ontology (GO) - Biological Process for MIR4677 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR4677 Gene

Drugs & Compounds for MIR4677 Gene

No Compound Related Data Available

Transcripts for MIR4677 Gene

mRNA/cDNA for MIR4677 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4677 Gene

No ASD Table

Relevant External Links for MIR4677 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR4677 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR4677 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4677 Gene:

genes like me logo Genes that share expression patterns with MIR4677: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4677 Gene

Orthologs for MIR4677 Gene

Evolution for MIR4677 Gene

Gene Tree for MIR4677 (if available)
Gene Tree for MIR4677 (if available)

No data available for Orthologs for MIR4677 Gene

Paralogs for MIR4677 Gene

No data available for Paralogs for MIR4677 Gene

Variants for MIR4677 Gene

Sequence variations from dbSNP and Humsavar for MIR4677 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs397515335 Pathogenic 243,344,278(+) AAAAG(-/G)AGCAC nc-transcript-variant, upstream-variant-2KB, reference, frameshift-variant
rs587777847 Pathogenic 243,344,302(+) CAAAA(-/A)CTAAC nc-transcript-variant, upstream-variant-2KB, reference, frameshift-variant
rs886038571 Likely benign 243,344,325(+) ATTAA(A/G)GATCA nc-transcript-variant, upstream-variant-2KB, reference, synonymous-codon
rs118064970 Uncertain significance 243,344,267(+) GGATG(A/G)GGCAG nc-transcript-variant, upstream-variant-2KB, reference, missense
rs759125934 Uncertain significance 243,344,262(+) GAGAA(A/G)GATGA nc-transcript-variant, upstream-variant-2KB, reference, synonymous-codon

Structural Variations from Database of Genomic Variants (DGV) for MIR4677 Gene

Variant ID Type Subtype PubMed ID
nsv833070 CNV gain 17160897
nsv517939 CNV gain 19592680
nsv1001488 CNV loss 25217958

Relevant External Links for MIR4677 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4677 Gene

Disorders for MIR4677 Gene

Relevant External Links for MIR4677

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR4677 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4677 Gene

Publications for MIR4677 Gene

  1. miRDeep2 accurately identifies known and hundreds of novel microRNA genes in seven animal clades. (PMID: 21911355) Friedländer MR … Rajewsky N (Nucleic acids research 2012) 3 60
  2. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3 60
  3. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H … Rovira C (Cancer research 2011) 3 60
  4. Deep sequencing of small RNAs from human skin reveals major alterations in the psoriasis miRNAome. (PMID: 21807764) Joyce CE … Bowcock AM (Human molecular genetics 2011) 3 60
  5. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 60

Products for MIR4677 Gene

Sources for MIR4677 Gene

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