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Aliases for MIR4674 Gene

Subcategory (RNA class) for MIR4674 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR4674 Gene

  • MicroRNA 4674 2 3
  • Hsa-Mir-4674 3

External Ids for MIR4674 Gene

Previous GeneCards Identifiers for MIR4674 Gene

  • GC09U901721
  • GC09M139442

Summaries for MIR4674 Gene

Entrez Gene Summary for MIR4674 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4674 Gene

MIR4674 (MicroRNA 4674) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4674 Gene

Genomics for MIR4674 Gene

Genomic Location for MIR4674 Gene

Start:
136,546,173 bp from pter
End:
136,546,259 bp from pter
Size:
87 bases
Orientation:
Minus strand

Genomic View for MIR4674 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR4674 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4674 Gene

ORGUL Member Location for MIR4674 Gene

ORGUL Member Location for MIR4674 gene

No data available for Regulatory Elements for MIR4674 Gene

Proteins for MIR4674 Gene

Post-translational modifications for MIR4674 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4674 Gene

Domains for MIR4674 Gene

Gene Families for MIR4674 Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4674: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4674 Gene

Function for MIR4674 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR4674 Gene

Localization for MIR4674 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4674 Gene

Pathways for MIR4674 Gene

SuperPathways for MIR4674 Gene

No Data Available

Interacting Proteins for MIR4674 Gene

Gene Ontology (GO) - Biological Process for MIR4674 Gene

None

No data available for Pathways by source for MIR4674 Gene

Transcripts for MIR4674 Gene

mRNA/cDNA for MIR4674 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4674 Gene

No ASD Table

Relevant External Links for MIR4674 Gene

GeneLoc Exon Structure for
MIR4674
ECgene alternative splicing isoforms for
MIR4674

Expression for MIR4674 Gene

No Expression Related Data Available

In Situ Assay Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for MIR4674 Gene

Orthologs for MIR4674 Gene

Evolution for MIR4674 Gene

ENSEMBL:
Gene Tree for MIR4674 (if available)
TreeFam:
Gene Tree for MIR4674 (if available)

No data available for Orthologs for MIR4674 Gene

Paralogs for MIR4674 Gene

No data available for Paralogs for MIR4674 Gene

Variants for MIR4674 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR4674 Gene

Variant ID Type Subtype PubMed ID
nsv894294 CNV Loss 21882294
dgv8385n71 CNV Loss 21882294
dgv8386n71 CNV Loss 21882294
dgv2426e1 CNV Complex 17122850
nsv469918 CNV Loss 18288195
dgv8394n71 CNV Loss 21882294
dgv8395n71 CNV Loss 21882294
dgv8396n71 CNV Loss 21882294
dgv8397n71 CNV Gain 21882294
nsv894373 CNV Loss 21882294
nsv894376 CNV Gain+Loss 21882294
esv30005 CNV Loss 17803354
nsv894377 CNV Loss 21882294
dgv8398n71 CNV Gain 21882294
nsv894379 CNV Gain+Loss 21882294
dgv8399n71 CNV Loss 21882294
dgv8400n71 CNV Loss 21882294
nsv894386 CNV Loss 21882294
nsv894387 CNV Gain 21882294
nsv8579 CNV Gain 18304495
nsv466673 CNV Gain 19166990
dgv8401n71 CNV Loss 21882294
dgv8402n71 CNV Loss 21882294
nsv509334 CNV Insertion 20534489
nsv6768 CNV Insertion 18451855

Relevant External Links for MIR4674 Gene

HapMap Linkage Disequilibrium report
MIR4674

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations from dbSNP and Humsavar for MIR4674 Gene

Disorders for MIR4674 Gene

No disorders were found for MIR4674 Gene.

No data available for UniProtKB/Swiss-Prot for MIR4674 Gene

Publications for MIR4674 Gene

  1. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  2. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H. … Rovira C. (Cancer Res. 2011) 3

Products for MIR4674 Gene

Sources for MIR4674 Gene

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