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Aliases for MIR4673 Gene

Subcategory (RNA class) for MIR4673 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4673 Gene

  • MicroRNA 4673 2 3 5
  • Hsa-Mir-4673 3

External Ids for MIR4673 Gene

Previous GeneCards Identifiers for MIR4673 Gene

  • GC09U901712
  • GC09M139416

Summaries for MIR4673 Gene

Entrez Gene Summary for MIR4673 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4673 Gene

MIR4673 (MicroRNA 4673) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4673 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4673 Gene

Genomics for MIR4673 Gene

Regulatory Elements for MIR4673 Gene

Enhancers for MIR4673 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH09H136514 1.3 Ensembl ENCODE dbSUPER 0.7 +1.2 1170 7 BCOR TFAP4 SAP130 ARID4B MAX ZMYM3 ZIC2 RAD21 BCL11B RARA SNAPC4 NALT1 FAM166A SEC16A SLC34A3 MIR4673
GH09H136524 1.8 FANTOM5 Ensembl ENCODE dbSUPER 0.4 -10.8 -10811 11 HDGF PKNOX1 RB1 KLF17 FEZF1 NFXL1 GLI4 RAD21 ZNF121 GLIS2 NALT1 NOTCH1 DNLZ SEC16A C9orf172 PTGDS LCNL1 NACC2 CARD9 MIR4673
GH09H136510 1.5 FANTOM5 ENCODE dbSUPER 0.4 +8.0 7966 3 HDAC1 PKNOX1 ATF1 NFRKB ZBTB40 TCF12 ZNF766 GATA2 ATF7 ETV6 SNAPC4 RABL6 EGFL7 PMPCA INPP5E DNLZ FAM69B TRAF2 MIR4673 SEC16A
GH09H136522 0.8 Ensembl dbSUPER 0.7 -2.9 -2934 0 POLR2A CEBPA CEBPB CEBPG NALT1 MIR4673 ENSG00000227512
GH09H136523 0.5 dbSUPER 0.7 -4.3 -4317 1 HIC1 CEBPB ZNF600 ZBTB33 NALT1 MIR4673 ENSG00000227512
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR4673 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR4673 Gene

Chromosome:
9
Start:
136,519,568 bp from pter
End:
136,519,626 bp from pter
Size:
59 bases
Orientation:
Minus strand

Genomic View for MIR4673 Gene

Genes around MIR4673 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4673 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4673 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4673 Gene

Proteins for MIR4673 Gene

Post-translational modifications for MIR4673 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4673 Gene

Domains & Families for MIR4673 Gene

Gene Families for MIR4673 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4673: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4673 Gene

Function for MIR4673 Gene

Phenotypes From GWAS Catalog for MIR4673 Gene

Animal Model Products

CRISPR Products

miRNA Products

Clone Products

  • Applied Biological Materials Clones for MIR4673
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4673 Gene

Localization for MIR4673 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4673 Gene

Pathways & Interactions for MIR4673 Gene

SuperPathways for MIR4673 Gene

No Data Available

Interacting Proteins for MIR4673 Gene

Gene Ontology (GO) - Biological Process for MIR4673 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4673 Gene

Drugs & Compounds for MIR4673 Gene

No Compound Related Data Available

Transcripts for MIR4673 Gene

mRNA/cDNA for MIR4673 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

miRNA Products

Clone Products

  • Applied Biological Materials Clones for MIR4673
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4673 Gene

No ASD Table

Relevant External Links for MIR4673 Gene

GeneLoc Exon Structure for
MIR4673
ECgene alternative splicing isoforms for
MIR4673

Expression for MIR4673 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR4673 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4673 Gene:

MIR4673
genes like me logo Genes that share expression patterns with MIR4673: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4673 Gene

Orthologs for MIR4673 Gene

Evolution for MIR4673 Gene

ENSEMBL:
Gene Tree for MIR4673 (if available)
TreeFam:
Gene Tree for MIR4673 (if available)

No data available for Orthologs for MIR4673 Gene

Paralogs for MIR4673 Gene

No data available for Paralogs for MIR4673 Gene

Variants for MIR4673 Gene

Sequence variations from dbSNP and Humsavar for MIR4673 Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type
rs587777735 Pathogenic 136,519,566(+) GAAGC(A/C)TGCCG downstream-variant-500B, splice-acceptor-variant
rs748001079 Likely benign 136,519,569(+) GCCTG(A/C)CGCAA intron-variant, nc-transcript-variant
rs61751556 Uncertain significance 136,519,483(+) TTCAC(A/G)CCGTC downstream-variant-500B, reference, synonymous-codon
rs763187824 Uncertain significance 136,519,533(+) ATCGT(C/T)GATAT downstream-variant-500B, reference, missense
rs369721921 untested 136,519,482(+) GTTCA(C/T)GCCGT downstream-variant-500B, reference, missense

Structural Variations from Database of Genomic Variants (DGV) for MIR4673 Gene

Variant ID Type Subtype PubMed ID
esv2759720 CNV loss 17122850
esv30005 CNV loss 17803354
nsv1161916 CNV deletion 26073780
nsv1161917 CNV deletion 26073780
nsv466673 CNV gain 19166990
nsv469918 CNV loss 18288195
nsv509334 CNV insertion 20534489
nsv615964 CNV loss 21841781
nsv615965 CNV loss 21841781
nsv615966 CNV gain 21841781
nsv615967 CNV loss 21841781
nsv6767 CNV insertion 18451855
nsv8579 CNV gain 18304495
nsv951202 CNV deletion 24416366

Relevant External Links for MIR4673 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4673

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4673 Gene

Disorders for MIR4673 Gene

Relevant External Links for MIR4673

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR4673

No disorders were found for MIR4673 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4673 Gene

Publications for MIR4673 Gene

  1. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H … Rovira C (Cancer research 2011) 3 60
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 60

Products for MIR4673 Gene

Sources for MIR4673 Gene

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