Free for academic non-profit institutions. Other users need a Commercial license

Aliases for MIR4669 Gene

Subcategory (RNA class) for MIR4669 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4669 Gene

  • MicroRNA 4669 2 3 5
  • Hsa-Mir-4669 3

External Ids for MIR4669 Gene

Previous GeneCards Identifiers for MIR4669 Gene

  • GC09U901715
  • GC09P137273

Summaries for MIR4669 Gene

Entrez Gene Summary for MIR4669 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4669 Gene

MIR4669 (MicroRNA 4669) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4669 Gene

Genomics for MIR4669 Gene

Regulatory Elements for MIR4669 Gene

Enhancers for MIR4669 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH09F134363 1.9 FANTOM5 Ensembl ENCODE 0.8 -3.3 -3311 25.4 MLX CREB3L1 ZFP64 YBX1 FEZF1 DMAP1 YY1 ZNF143 ZNF263 SP3 RXRA ENSG00000273249 LINC00094 SURF4 MIR4669
GH09F134389 1.7 FANTOM5 Ensembl ENCODE 0.4 +14.8 14790 9.6 HDGF PKNOX1 CREB3L1 ARID4B SIN3A DMAP1 ZNF2 ZNF48 ZNF143 ZNF207 ENSG00000273249 RXRA BRD3 MIR4669 LOC105376311
GH09F134402 1.8 FANTOM5 Ensembl ENCODE 0.3 +29.3 29262 13.3 HDGF ARNT CREB3L1 ZFP64 SIN3A DMAP1 ZNF2 YY1 ZNF766 ZNF143 RNU6ATAC ARF4P1 MIR3689B ENSG00000235572 ENSG00000273249 LINC00094 RXRA MIR4669 LOC105376311
GH09F134337 1.8 FANTOM5 Ensembl ENCODE 0.3 -36.9 -36911 9.4 HDGF PKNOX1 ARNT MLX CREB3L1 ARID4B SIN3A DMAP1 SLC30A9 CBX5 RNU6ATAC ARF4P1 MIR3689B RXRA COL5A1-AS1 MIR4669
GH09F134352 1.6 FANTOM5 Ensembl ENCODE 0.3 -22.3 -22311 9.8 PKNOX1 ZFP64 ARID4B SIN3A ZNF121 GLIS2 GATA2 ZNF207 FOS KLF13 RXRA ENSG00000273249 MIR4669
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR4669 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR4669 Gene

Chromosome:
9
Start:
134,379,411 bp from pter
End:
134,379,472 bp from pter
Size:
62 bases
Orientation:
Plus strand

Genomic View for MIR4669 Gene

Genes around MIR4669 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4669 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4669 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4669 Gene

Proteins for MIR4669 Gene

Post-translational modifications for MIR4669 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4669 Gene

Domains & Families for MIR4669 Gene

Gene Families for MIR4669 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4669: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4669 Gene

Function for MIR4669 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4669 Gene

Localization for MIR4669 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4669 Gene

Pathways & Interactions for MIR4669 Gene

SuperPathways for MIR4669 Gene

No Data Available

Interacting Proteins for MIR4669 Gene

Gene Ontology (GO) - Biological Process for MIR4669 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4669 Gene

Transcripts for MIR4669 Gene

mRNA/cDNA for MIR4669 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4669 Gene

No ASD Table

Relevant External Links for MIR4669 Gene

GeneLoc Exon Structure for
MIR4669
ECgene alternative splicing isoforms for
MIR4669

Expression for MIR4669 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4669 Gene:

MIR4669
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR4669 Gene

Orthologs for MIR4669 Gene

Evolution for MIR4669 Gene

ENSEMBL:
Gene Tree for MIR4669 (if available)
TreeFam:
Gene Tree for MIR4669 (if available)

No data available for Orthologs for MIR4669 Gene

Paralogs for MIR4669 Gene

No data available for Paralogs for MIR4669 Gene

Variants for MIR4669 Gene

Sequence variations from dbSNP and Humsavar for MIR4669 Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type
rs111496711 -- 134,379,471(+) GAGGG(-/A)CCCCC intron-variant, nc-transcript-variant, utr-variant-5-prime
rs112010142 -- 134,378,350(+) TGCCG(-/GCCAGCGCCTGTGT)GCCAG intron-variant, upstream-variant-2KB
rs112170486 -- 134,379,228(+) TTCCT(-/GATCCCTGTGG)GCTCC intron-variant, upstream-variant-2KB
rs113941333 -- 134,379,171(+) GGACC(C/T)GGAAT intron-variant, upstream-variant-2KB
rs114051128 -- 134,378,798(+) GCACC(C/T)CAGCC intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR4669 Gene

Variant ID Type Subtype PubMed ID
nsv951809 CNV deletion 24416366
nsv615805 CNV loss 21841781
nsv469908 CNV loss 18288195
nsv1125319 OTHER inversion 24896259
nsv1053733 CNV gain 25217958
esv2739138 CNV deletion 23290073
dgv7723n100 CNV gain 25217958
dgv7722n100 CNV gain 25217958

Relevant External Links for MIR4669 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4669

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4669 Gene

Disorders for MIR4669 Gene

Relevant External Links for MIR4669

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR4669

No disorders were found for MIR4669 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4669 Gene

Publications for MIR4669 Gene

  1. Genome-wide association study of intelligence: additive effects of novel brain expressed genes. (PMID: 22449649) Loo S.K. … Nelson S.F. (J Am Acad Child Adolesc Psychiatry 2012) 3 64
  2. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H. … Rovira C. (Cancer Res. 2011) 3 64
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4669 Gene

Sources for MIR4669 Gene

Content
Loading form....