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Aliases for MIR4669 Gene

Subcategory (RNA class) for MIR4669 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4669 Gene

  • MicroRNA 4669 2 3 5
  • Hsa-Mir-4669 3

External Ids for MIR4669 Gene

Previous GeneCards Identifiers for MIR4669 Gene

  • GC09U901715
  • GC09P137273

Summaries for MIR4669 Gene

Entrez Gene Summary for MIR4669 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4669 Gene

MIR4669 (MicroRNA 4669) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4669 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4669 Gene

Genomics for MIR4669 Gene

GeneHancer (GH) Regulatory Elements for MIR4669 Gene

Promoters and enhancers for MIR4669 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH09I134369 Enhancer 1.8 FANTOM5 Ensembl ENCODE dbSUPER 550.8 -0.7 -677 18.8 PKNOX1 CLOCK FOXA2 MLX ZFP64 ARID4B SIN3A FEZF1 DMAP1 ZBTB7B MIR4669 RXRA ENSG00000273249 LOC100130548 WDR5 BRD3
GH09I134390 Enhancer 1.6 FANTOM5 Ensembl ENCODE dbSUPER 0.4 +12.8 12848 4.2 HDGF PKNOX1 RB1 BMI1 BATF KLF5 IRF4 ZNF207 ZNF143 ATF7 ENSG00000273249 BRD3 MIR4669 RXRA LOC105376311
GH09I134363 Enhancer 1.6 FANTOM5 Ensembl ENCODE dbSUPER 0.4 -13.2 -13172 5.4 HDGF PKNOX1 CLOCK ARID4B NEUROD1 SIN3A YBX1 DMAP1 ZBTB7B YY1 WDR5 BRD3OS OLFM1 BRD3 RXRA SURF4 COL5A1 MIR4669
GH09I134394 Enhancer 1.4 FANTOM5 Ensembl ENCODE dbSUPER 0.4 +16.8 16789 3.6 HDGF CTCF NCOA3 MAX ZMYM3 EBF1 E4F1 RELA POLR2A ATF7 RXRA BRD3 MIR4669 LOC105376311
GH09I134402 Enhancer 1.7 FANTOM5 Ensembl ENCODE dbSUPER 0.3 +29.3 29262 13.3 HDGF FOXA2 CLOCK NEUROD1 SIN3A ZBTB7B ZNF207 ZNF143 FOS ZNF592 ENSG00000273249 COL5A1 BRD3 RXRA MIR4669 LOC105376311
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR4669 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR4669 Gene

Genomic Locations for MIR4669 Gene
chr9:134,379,411-134,379,472
(GRCh38/hg38)
Size:
62 bases
Orientation:
Plus strand
chr9:137,271,257-137,271,318
(GRCh37/hg19)

Genomic View for MIR4669 Gene

Genes around MIR4669 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4669 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4669 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4669 Gene

Proteins for MIR4669 Gene

Post-translational modifications for MIR4669 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4669 Gene

Domains & Families for MIR4669 Gene

Gene Families for MIR4669 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4669: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4669 Gene

Function for MIR4669 Gene

Phenotypes From GWAS Catalog for MIR4669 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4669 Gene

Localization for MIR4669 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4669 Gene

Pathways & Interactions for MIR4669 Gene

SuperPathways for MIR4669 Gene

No Data Available

Interacting Proteins for MIR4669 Gene

Gene Ontology (GO) - Biological Process for MIR4669 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4669 Gene

Drugs & Compounds for MIR4669 Gene

No Compound Related Data Available

Transcripts for MIR4669 Gene

mRNA/cDNA for MIR4669 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4669 Gene

No ASD Table

Relevant External Links for MIR4669 Gene

GeneLoc Exon Structure for
MIR4669
ECgene alternative splicing isoforms for
MIR4669

Expression for MIR4669 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4669 Gene:

MIR4669
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4669 Gene

Orthologs for MIR4669 Gene

Evolution for MIR4669 Gene

ENSEMBL:
Gene Tree for MIR4669 (if available)
TreeFam:
Gene Tree for MIR4669 (if available)

No data available for Orthologs for MIR4669 Gene

Paralogs for MIR4669 Gene

No data available for Paralogs for MIR4669 Gene

Variants for MIR4669 Gene

Sequence variations from dbSNP and Humsavar for MIR4669 Gene

SNP ID Clin Chr 09 pos Variation AA Info Type
rs1000850073 -- 134,378,019(+) T/C upstream_transcript_variant
rs1000922175 -- 134,377,845(+) T/C upstream_transcript_variant
rs1001988794 -- 134,379,880(+) C/T downstream_transcript_variant
rs1002140956 -- 134,377,603(+) A/G upstream_transcript_variant
rs1002925917 -- 134,379,864(+) CC/C downstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR4669 Gene

Variant ID Type Subtype PubMed ID
dgv7722n100 CNV gain 25217958
dgv7723n100 CNV gain 25217958
esv2739138 CNV deletion 23290073
nsv1053733 CNV gain 25217958
nsv1125319 OTHER inversion 24896259
nsv469908 CNV loss 18288195
nsv615805 CNV loss 21841781
nsv951809 CNV deletion 24416366

Additional Variant Information for MIR4669 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4669

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4669 Gene

Disorders for MIR4669 Gene

Additional Disease Information for MIR4669

No disorders were found for MIR4669 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4669 Gene

Publications for MIR4669 Gene

  1. Genome-wide association study of intelligence: additive effects of novel brain expressed genes. (PMID: 22449649) Loo SK … Nelson SF (Journal of the American Academy of Child and Adolescent Psychiatry 2012) 3 58
  2. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H … Rovira C (Cancer research 2011) 3 58
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR4669 Gene

Sources for MIR4669 Gene

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