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Aliases for MIR4666A Gene

Subcategory (RNA class) for MIR4666A Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4666A Gene

  • MicroRNA 4666a 2 3 5
  • MicroRNA 4666 2 3
  • Hsa-Mir-4666a 3
  • Hsa-Mir-4666 3
  • MIR4666 3

External Ids for MIR4666A Gene

Previous HGNC Symbols for MIR4666A Gene

  • MIR4666

Previous GeneCards Identifiers for MIR4666A Gene

  • GC01U903301
  • GC01P228654

Summaries for MIR4666A Gene

Entrez Gene Summary for MIR4666A Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4666A Gene

MIR4666A (MicroRNA 4666a) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4666A Gene

Genomics for MIR4666A Gene

Genomic Location for MIR4666A Gene

Chromosome:
1
Start:
228,462,074 bp from pter
End:
228,462,152 bp from pter
Size:
79 bases
Orientation:
Plus strand

Genomic View for MIR4666A Gene

Genes around MIR4666A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4666A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4666A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4666A Gene

No data available for Regulatory Elements for MIR4666A Gene

Proteins for MIR4666A Gene

Post-translational modifications for MIR4666A Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4666A Gene

Domains & Families for MIR4666A Gene

Gene Families for MIR4666A Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4666A: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4666A Gene

Function for MIR4666A Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4666A Gene

Localization for MIR4666A Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4666A Gene

Pathways & Interactions for MIR4666A Gene

SuperPathways for MIR4666A Gene

No Data Available

Interacting Proteins for MIR4666A Gene

Gene Ontology (GO) - Biological Process for MIR4666A Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4666A Gene

Drugs & Compounds for MIR4666A Gene

No Compound Related Data Available

Transcripts for MIR4666A Gene

mRNA/cDNA for MIR4666A Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4666A Gene

No ASD Table

Relevant External Links for MIR4666A Gene

GeneLoc Exon Structure for
MIR4666A
ECgene alternative splicing isoforms for
MIR4666A

Expression for MIR4666A Gene

mRNA expression in normal human tissues for MIR4666A Gene

genes like me logo Genes that share expression patterns with MIR4666A: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MIR4666A Gene

Orthologs for MIR4666A Gene

Evolution for MIR4666A Gene

ENSEMBL:
Gene Tree for MIR4666A (if available)
TreeFam:
Gene Tree for MIR4666A (if available)

No data available for Orthologs for MIR4666A Gene

Paralogs for MIR4666A Gene

No data available for Paralogs for MIR4666A Gene

Variants for MIR4666A Gene

Sequence variations from dbSNP and Humsavar for MIR4666A Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs16841344 -- 228,462,027(+) CCAAA(A/T)TTTTA upstream-variant-2KB
rs35692711 -- 228,461,690(+) GGCTG(G/T)CTTTT upstream-variant-2KB
rs73101117 -- 228,460,926(+) TGAAA(C/T)TGACT upstream-variant-2KB
rs77127974 -- 228,460,547(+) TACAA(A/G)TACCA upstream-variant-2KB
rs78933032 -- 228,461,624(+) TCAAA(C/T)GTCAG upstream-variant-2KB

Relevant External Links for MIR4666A Gene

HapMap Linkage Disequilibrium report
MIR4666A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR4666A Gene

Disorders for MIR4666A Gene

Relevant External Links for MIR4666A

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR4666A

No disorders were found for MIR4666A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4666A Gene

Publications for MIR4666A Gene

  1. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H. … Rovira C. (Cancer Res. 2011) 3 67
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3

Products for MIR4666A Gene

Sources for MIR4666A Gene

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