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Aliases for MIR4665 Gene

Subcategory (RNA class) for MIR4665 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4665 Gene

  • MicroRNA 4665 2 3 5
  • Hsa-Mir-4665 3
  • Mir-4665 3

External Ids for MIR4665 Gene

Previous GeneCards Identifiers for MIR4665 Gene

  • GC09U901706

Summaries for MIR4665 Gene

Entrez Gene Summary for MIR4665 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4665 Gene

MIR4665 (MicroRNA 4665) is an RNA Gene, and is affiliated with the miRNA class.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4665 Gene

Genomics for MIR4665 Gene

Regulatory Elements for MIR4665 Gene

Enhancers for MIR4665 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH09G006006 1.1 ENCODE 0.7 +0.1 117 3.4 HDGF PKNOX1 AGO1 ARID4B SIN3A YY1 ZNF207 DEK ZNF263 SP3 ERMP1 KIAA2026 MIR4665
GH09G005976 0.9 Ensembl ENCODE 0.3 -30.9 -30885 1.2 CTCF PKNOX1 TRIM22 TBX21 RAD21 IKZF1 TARDBP ZNF143 NBN SMC3 ERMP1 MIR4665 GC09M005936
GH09G005949 1.1 Ensembl ENCODE 0.2 -58.4 -58426 0.8 HDAC1 FEZF1 RELB IKZF2 ZNF362 CEBPB ELF1 ZEB2 TSHZ1 TBX21 ERMP1 GC09M005936 MIR4665
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR4665 on UCSC Golden Path with GeneCards custom track

Promoters for MIR4665 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000232894 -126 2601 HDGF PKNOX1 AGO1 ARID4B SIN3A YY1 ZNF207 DEK ZNF263 SP3

Genomic Location for MIR4665 Gene

Chromosome:
9
Start:
6,007,826 bp from pter
End:
6,007,904 bp from pter
Size:
79 bases
Orientation:
Plus strand

Genomic View for MIR4665 Gene

Genes around MIR4665 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4665 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4665 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4665 Gene

Proteins for MIR4665 Gene

Post-translational modifications for MIR4665 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4665 Gene

Domains & Families for MIR4665 Gene

Gene Families for MIR4665 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4665: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4665 Gene

Function for MIR4665 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4665 Gene

Localization for MIR4665 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4665 Gene

Pathways & Interactions for MIR4665 Gene

SuperPathways for MIR4665 Gene

No Data Available

Interacting Proteins for MIR4665 Gene

Gene Ontology (GO) - Biological Process for MIR4665 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4665 Gene

Drugs & Compounds for MIR4665 Gene

No Compound Related Data Available

Transcripts for MIR4665 Gene

mRNA/cDNA for MIR4665 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4665 Gene

No ASD Table

Relevant External Links for MIR4665 Gene

GeneLoc Exon Structure for
MIR4665
ECgene alternative splicing isoforms for
MIR4665

Expression for MIR4665 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR4665 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4665 Gene:

MIR4665
genes like me logo Genes that share expression patterns with MIR4665: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4665 Gene

Orthologs for MIR4665 Gene

Evolution for MIR4665 Gene

ENSEMBL:
Gene Tree for MIR4665 (if available)
TreeFam:
Gene Tree for MIR4665 (if available)

No data available for Orthologs for MIR4665 Gene

Paralogs for MIR4665 Gene

No data available for Paralogs for MIR4665 Gene

Variants for MIR4665 Gene

Sequence variations from dbSNP and Humsavar for MIR4665 Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type
rs1000421328 -- 6,006,736(+) GGTAG(C/T)AAATG intron-variant, upstream-variant-2KB
rs1000707063 -- 6,007,891(+) TAGCC(C/G)CCGCC nc-transcript-variant, utr-variant-5-prime
rs1000776152 -- 6,006,913(+) ATTCT(C/T)CCTAC intron-variant, upstream-variant-2KB
rs1001822338 -- 6,007,414(+) GACCG(C/G)CCCGG nc-transcript-variant, upstream-variant-2KB, reference, missense
rs1002148950 -- 6,008,248(+) TCCTC(C/G)TCTCC nc-transcript-variant, downstream-variant-500B, upstream-variant-2KB, utr-variant-5-prime

Structural Variations from Database of Genomic Variants (DGV) for MIR4665 Gene

Variant ID Type Subtype PubMed ID
nsv1015450 CNV loss 25217958
nsv1029665 CNV gain 25217958

Relevant External Links for MIR4665 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4665

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4665 Gene

Disorders for MIR4665 Gene

Relevant External Links for MIR4665

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR4665

No disorders were found for MIR4665 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4665 Gene

Publications for MIR4665 Gene

  1. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A. … Griffiths-Jones S. (Nucleic Acids Res. 2011) 3 64
  2. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H. … Rovira C. (Cancer Res. 2011) 3 64
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4665 Gene

Sources for MIR4665 Gene

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