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Aliases for MIR4664 Gene

Subcategory (RNA class) for MIR4664 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4664 Gene

  • MicroRNA 4664 2 3 5
  • Hsa-Mir-4664 3

External Ids for MIR4664 Gene

Previous GeneCards Identifiers for MIR4664 Gene

  • GC08U901559
  • GC08M144818

Summaries for MIR4664 Gene

Entrez Gene Summary for MIR4664 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4664 Gene

MIR4664 (MicroRNA 4664) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4664 Gene

Genomics for MIR4664 Gene

Regulatory Elements for MIR4664 Gene

Enhancers for MIR4664 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH08F143725 0.2 Ensembl 0.4 +5.0 5004 5.2 RING1 PAF1 NR3C1 BCL11B ZNF121 HNF4G ZBTB33 KDM6A ENSG00000254548 LRRC14 LOC105375803 ZNF696 FAM83H-AS1 ZNF623 CYHR1 VPS28 ENSG00000254973 EPPK1
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around MIR4664 on UCSC Golden Path with GeneCards custom track

Promoters for MIR4664 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00001446390 -447 1601 ATF1 ARID4B SIN3A ZNF48 ETS1 ELK1 KDM4B SP5 MIER2 ZNF518A

Genomic Location for MIR4664 Gene

Chromosome:
8
Start:
143,733,083 bp from pter
End:
143,733,153 bp from pter
Size:
71 bases
Orientation:
Minus strand

Genomic View for MIR4664 Gene

Genes around MIR4664 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4664 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4664 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4664 Gene

Proteins for MIR4664 Gene

Post-translational modifications for MIR4664 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4664 Gene

Domains & Families for MIR4664 Gene

Gene Families for MIR4664 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4664: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4664 Gene

Function for MIR4664 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4664 Gene

Localization for MIR4664 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4664 Gene

Pathways & Interactions for MIR4664 Gene

SuperPathways for MIR4664 Gene

No Data Available

Interacting Proteins for MIR4664 Gene

Gene Ontology (GO) - Biological Process for MIR4664 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4664 Gene

Transcripts for MIR4664 Gene

mRNA/cDNA for MIR4664 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4664 Gene

No ASD Table

Relevant External Links for MIR4664 Gene

GeneLoc Exon Structure for
MIR4664
ECgene alternative splicing isoforms for
MIR4664

Expression for MIR4664 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR4664 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4664 Gene:

MIR4664
genes like me logo Genes that share expression patterns with MIR4664: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR4664 Gene

Orthologs for MIR4664 Gene

Evolution for MIR4664 Gene

ENSEMBL:
Gene Tree for MIR4664 (if available)
TreeFam:
Gene Tree for MIR4664 (if available)

No data available for Orthologs for MIR4664 Gene

Paralogs for MIR4664 Gene

No data available for Paralogs for MIR4664 Gene

Variants for MIR4664 Gene

Sequence variations from dbSNP and Humsavar for MIR4664 Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type
rs111323165 -- 143,733,421(+) ACCCG(G/T)ATCCC intron-variant, upstream-variant-2KB, utr-variant-5-prime
rs114385391 -- 143,732,604(+) GCCCC(C/G)GTGGC intron-variant, downstream-variant-500B, upstream-variant-2KB, utr-variant-5-prime
rs114452617 -- 143,734,418(+) GTCCC(C/T)CATCT intron-variant, upstream-variant-2KB
rs12676028 -- 143,732,592(+) CAGAC(A/G)GTGGA intron-variant, downstream-variant-500B, upstream-variant-2KB, utr-variant-5-prime
rs138159241 -- 143,732,737(+) AGCCA(C/T)TCCCG intron-variant, downstream-variant-500B, upstream-variant-2KB, utr-variant-5-prime

Structural Variations from Database of Genomic Variants (DGV) for MIR4664 Gene

Variant ID Type Subtype PubMed ID
nsv466007 CNV loss 19166990
nsv519816 CNV loss 19592680
nsv612893 CNV loss 21841781
nsv612895 CNV loss 21841781
nsv6441 CNV insertion 18451855

Relevant External Links for MIR4664 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4664

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4664 Gene

Disorders for MIR4664 Gene

Relevant External Links for MIR4664

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR4664

No disorders were found for MIR4664 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4664 Gene

Publications for MIR4664 Gene

  1. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H. … Rovira C. (Cancer Res. 2011) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4664 Gene

Sources for MIR4664 Gene

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