Free for academic non-profit institutions. Other users need a Commercial license

Aliases for MIR4663 Gene

Subcategory (RNA class) for MIR4663 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4663 Gene

  • MicroRNA 4663 2 3 5
  • Hsa-Mir-4663 3

External Ids for MIR4663 Gene

Previous GeneCards Identifiers for MIR4663 Gene

  • GC08U901567
  • GC08M124230

Summaries for MIR4663 Gene

Entrez Gene Summary for MIR4663 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4663 Gene

MIR4663 (MicroRNA 4663) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4663 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4663 Gene

Genomics for MIR4663 Gene

Regulatory Elements for MIR4663 Gene

Enhancers for MIR4663 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH08H123204 0.8 ENCODE 0.4 +10.6 10578 1 SOX13 CTCF FOXA2 SAP130 ARID4B MAX CEBPG DMAP1 THRB RAD21 FAM83A-AS1 MIR4663
GH08H123207 0.4 ENCODE 0.4 +8.7 8678 0 ZBTB33 FAM83A-AS1 MIR4663
GH08H123202 0.4 ENCODE 0.4 +12.9 12874 0 CREB1 FAM83A-AS1 MIR4663
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR4663 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR4663 Gene

Chromosome:
8
Start:
123,215,788 bp from pter
End:
123,215,863 bp from pter
Size:
76 bases
Orientation:
Minus strand

Genomic View for MIR4663 Gene

Genes around MIR4663 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4663 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4663 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4663 Gene

Proteins for MIR4663 Gene

Post-translational modifications for MIR4663 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4663 Gene

Domains & Families for MIR4663 Gene

Gene Families for MIR4663 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4663: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4663 Gene

Function for MIR4663 Gene

Animal Model Products

CRISPR Products

miRNA Products

Clone Products

  • Applied Biological Materials Clones for MIR4663
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4663 Gene

Localization for MIR4663 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4663 Gene

Pathways & Interactions for MIR4663 Gene

SuperPathways for MIR4663 Gene

No Data Available

Interacting Proteins for MIR4663 Gene

Gene Ontology (GO) - Biological Process for MIR4663 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4663 Gene

Drugs & Compounds for MIR4663 Gene

No Compound Related Data Available

Transcripts for MIR4663 Gene

mRNA/cDNA for MIR4663 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

miRNA Products

Clone Products

  • Applied Biological Materials Clones for MIR4663
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4663 Gene

No ASD Table

Relevant External Links for MIR4663 Gene

GeneLoc Exon Structure for
MIR4663
ECgene alternative splicing isoforms for
MIR4663

Expression for MIR4663 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4663 Gene:

MIR4663
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4663 Gene

Orthologs for MIR4663 Gene

Evolution for MIR4663 Gene

ENSEMBL:
Gene Tree for MIR4663 (if available)
TreeFam:
Gene Tree for MIR4663 (if available)

No data available for Orthologs for MIR4663 Gene

Paralogs for MIR4663 Gene

No data available for Paralogs for MIR4663 Gene

Variants for MIR4663 Gene

Sequence variations from dbSNP and Humsavar for MIR4663 Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type
rs1000241136 -- 123,217,345(+) GCATC(A/G)GAGTT upstream-variant-2KB
rs1000927331 -- 123,215,750(+) GGACA(A/G)GCTGT downstream-variant-500B
rs1001759093 -- 123,215,704(+) TGCAG(C/G)GTACA downstream-variant-500B
rs1001789016 -- 123,217,754(+) AGATG(C/G)CAGGT upstream-variant-2KB
rs1005010614 -- 123,216,473(+) AAAAA(A/T)TTTGT upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR4663 Gene

Variant ID Type Subtype PubMed ID
esv3618664 CNV loss 21293372
nsv1032827 CNV gain 25217958

Relevant External Links for MIR4663 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4663

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4663 Gene

Disorders for MIR4663 Gene

Relevant External Links for MIR4663

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR4663

No disorders were found for MIR4663 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4663 Gene

Publications for MIR4663 Gene

  1. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H … Rovira C (Cancer research 2011) 3 60
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 60

Products for MIR4663 Gene

Sources for MIR4663 Gene

Content
Loading form....