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Aliases for MIR4662B Gene

Subcategory (RNA class) for MIR4662B Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR4662B Gene

  • MicroRNA 4662b 2 3
  • Hsa-Mir-4662b 3

External Ids for MIR4662B Gene

Previous GeneCards Identifiers for MIR4662B Gene

  • GC08U901564
  • GC08M125836

Summaries for MIR4662B Gene

Entrez Gene Summary for MIR4662B Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4662B Gene

MIR4662B (MicroRNA 4662b) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4662B Gene

Genomics for MIR4662B Gene

Genomic Location for MIR4662B Gene

Chromosome:
8
Start:
124,821,978 bp from pter
End:
124,822,058 bp from pter
Size:
81 bases
Orientation:
Minus strand

Genomic View for MIR4662B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR4662B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4662B Gene

ORGUL Member Location for MIR4662B Gene

ORGUL Member Location for MIR4662B gene

No data available for Regulatory Elements for MIR4662B Gene

Proteins for MIR4662B Gene

Post-translational modifications for MIR4662B Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4662B Gene

Domains & Families for MIR4662B Gene

Gene Families for MIR4662B Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4662B: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4662B Gene

Function for MIR4662B Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4662B Gene

Localization for MIR4662B Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4662B Gene

Pathways & Interactions for MIR4662B Gene

SuperPathways for MIR4662B Gene

No Data Available

Interacting Proteins for MIR4662B Gene

Gene Ontology (GO) - Biological Process for MIR4662B Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4662B Gene

Drugs & Compounds for MIR4662B Gene

No Compound Related Data Available

Transcripts for MIR4662B Gene

mRNA/cDNA for MIR4662B Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4662B Gene

No ASD Table

Relevant External Links for MIR4662B Gene

GeneLoc Exon Structure for
MIR4662B
ECgene alternative splicing isoforms for
MIR4662B

Expression for MIR4662B Gene

mRNA expression in normal human tissues for MIR4662B Gene

genes like me logo Genes that share expression patterns with MIR4662B: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MIR4662B Gene

Orthologs for MIR4662B Gene

Evolution for MIR4662B Gene

ENSEMBL:
Gene Tree for MIR4662B (if available)
TreeFam:
Gene Tree for MIR4662B (if available)

No data available for Orthologs for MIR4662B Gene

Paralogs for MIR4662B Gene

No data available for Paralogs for MIR4662B Gene

Variants for MIR4662B Gene

Sequence variations from dbSNP and Humsavar for MIR4662B Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type MAF
rs7820033 -- 124,823,876(+) TGGCA(A/G)GACTC upstream-variant-2KB
rs10956215 -- 124,823,747(+) TTCTC(C/T)GCATT upstream-variant-2KB
rs11989025 -- 124,823,855(+) CTATT(A/C)GCACG upstream-variant-2KB
rs13257530 -- 124,823,736(+) ATGTC(C/G)TACAA upstream-variant-2KB
rs34149428 -- 124,822,844(+) GAGTA(-/G)CAATT upstream-variant-2KB

Relevant External Links for MIR4662B Gene

HapMap Linkage Disequilibrium report
MIR4662B

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR4662B Gene

Disorders for MIR4662B Gene

Relevant External Links for MIR4662B

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR4662B
genes like me logo Genes that share disorders with MIR4662B: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4662B Gene

Publications for MIR4662B Gene

  1. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H. … Rovira C. (Cancer Res. 2011) 67
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 67

Products for MIR4662B Gene

Sources for MIR4662B Gene

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