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Aliases for MIR4662A Gene

Subcategory (RNA class) for MIR4662A Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4662A Gene

  • MicroRNA 4662a 2 3 5
  • Hsa-Mir-4662a 3

External Ids for MIR4662A Gene

Previous GeneCards Identifiers for MIR4662A Gene

  • GC08U901553
  • GC08M125837
  • GC08P125837

Summaries for MIR4662A Gene

Entrez Gene Summary for MIR4662A Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4662A Gene

MIR4662A (MicroRNA 4662a) is an RNA Gene, and is affiliated with the miRNA class.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4662A Gene

Genomics for MIR4662A Gene

Regulatory Elements for MIR4662A Gene

Enhancers for MIR4662A Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH08G124814 1.4 Ensembl ENCODE dbSUPER 0.4 -6.7 -6708 2.1 HNRNPUL1 ARNT FOS KDM4B GTF2B MEF2D MBD2 MYNN GTF2E2 BACH1 MTSS1 ZNF572 LOC105375744 SQLE MIR4662A GC08P124786
GH08G124789 1.7 FANTOM5 Ensembl ENCODE dbSUPER 0.3 -31.7 -31694 2.3 ELF3 CTCF TFAP4 KLF1 SAP130 INSM2 ZNF76 KLF17 CEBPG RAD21 NSMCE2 MTSS1 WASHC5 RNF139 GC08P124786 MIR4662A
GH08G124817 0.7 dbSUPER 0.7 -4.6 -4567 0.6 CTCF PKNOX1 NR2F1 ZNF175 MAFG CEBPG ZEB2 JUND ZNF589 IKZF1 MTSS1 ZNF572 LOC105375744 SQLE MIR4662A GC08P124786
GH08G124802 0.9 FANTOM5 dbSUPER 0.4 -19.0 -18970 0.2 FOSL1 ZNF316 ATF3 YBX1 FOS NSMCE2 MTSS1 RNF139 WASHC5 ZNF572 GC08P124786 MIR4662A
GH08G124797 0.8 dbSUPER 0.3 -23.4 -23414 1.8 ELF3 SOX13 SAP130 MLX ARID4B RAD21 ZNF644 THRB ZNF48 RARA GC08P124786 MIR4662A
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR4662A on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR4662A Gene

Chromosome:
8
Start:
124,821,985 bp from pter
End:
124,822,051 bp from pter
Size:
67 bases
Orientation:
Plus strand

Genomic View for MIR4662A Gene

Genes around MIR4662A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4662A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4662A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4662A Gene

Proteins for MIR4662A Gene

Post-translational modifications for MIR4662A Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4662A Gene

Domains & Families for MIR4662A Gene

Gene Families for MIR4662A Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4662A: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4662A Gene

Function for MIR4662A Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4662A Gene

Localization for MIR4662A Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4662A Gene

Pathways & Interactions for MIR4662A Gene

SuperPathways for MIR4662A Gene

No Data Available

Interacting Proteins for MIR4662A Gene

Gene Ontology (GO) - Biological Process for MIR4662A Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4662A Gene

Drugs & Compounds for MIR4662A Gene

No Compound Related Data Available

Transcripts for MIR4662A Gene

mRNA/cDNA for MIR4662A Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4662A Gene

No ASD Table

Relevant External Links for MIR4662A Gene

GeneLoc Exon Structure for
MIR4662A
ECgene alternative splicing isoforms for
MIR4662A

Expression for MIR4662A Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4662A Gene:

MIR4662A
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4662A Gene

Orthologs for MIR4662A Gene

Evolution for MIR4662A Gene

ENSEMBL:
Gene Tree for MIR4662A (if available)
TreeFam:
Gene Tree for MIR4662A (if available)

No data available for Orthologs for MIR4662A Gene

Paralogs for MIR4662A Gene

No data available for Paralogs for MIR4662A Gene

Variants for MIR4662A Gene

Sequence variations from dbSNP and Humsavar for MIR4662A Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type
rs1005115579 -- 124,821,001(+) TTTTA(-/G)AATAA upstream-variant-2KB
rs1006121106 -- 124,822,444(+) AAAAA(A/G)TGCCA downstream-variant-500B, upstream-variant-2KB
rs1008118159 -- 124,822,289(+) GAGGC(A/G)GGCAC downstream-variant-500B, upstream-variant-2KB
rs1008477719 -- 124,820,400(+) TGCTG(C/G)GATTA upstream-variant-2KB
rs1009916911 -- 124,822,101(+) AAAAC(A/T)TCAAG downstream-variant-500B, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR4662A Gene

Variant ID Type Subtype PubMed ID
esv3891476 CNV gain 25118596

Relevant External Links for MIR4662A Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4662A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4662A Gene

Disorders for MIR4662A Gene

Relevant External Links for MIR4662A

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR4662A

No disorders were found for MIR4662A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4662A Gene

Publications for MIR4662A Gene

  1. miRDeep2 accurately identifies known and hundreds of novel microRNA genes in seven animal clades. (PMID: 21911355) FriedlAonder M.R. … Rajewsky N. (Nucleic Acids Res. 2012) 3 64
  2. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H. … Rovira C. (Cancer Res. 2011) 3 64
  3. Deep sequencing of small RNAs from human skin reveals major alterations in the psoriasis miRNAome. (PMID: 21807764) Joyce C.E. … Bowcock A.M. (Hum. Mol. Genet. 2011) 3 64
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4662A Gene

Sources for MIR4662A Gene

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