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Aliases for MIR4661 Gene

Subcategory (RNA class) for MIR4661 Gene


Quality Score for this RNA gene is


Aliases for MIR4661 Gene

  • MicroRNA 4661 2 3 5
  • Hsa-Mir-4661 3

External Ids for MIR4661 Gene

Previous GeneCards Identifiers for MIR4661 Gene

  • GC08U901556
  • GC08P092223

Summaries for MIR4661 Gene

Entrez Gene Summary for MIR4661 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4661 Gene

MIR4661 (MicroRNA 4661) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4661 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4661 Gene

Genomics for MIR4661 Gene

Regulatory Elements for MIR4661 Gene

Enhancers for MIR4661 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH08H091207 0.8 ENCODE 0.7 +2.3 2251 1.2 ELF3 FOXA2 THRB RARA CREM MIXL1 THAP11 CEBPB NFIL3 MIER3 MIR4661 SLC26A7
GH08H091205 0.6 ENCODE 0.7 0.0 -38 0.2 PKNOX1 SIN3A USF2 MNT ZEB1 FOXA1 SREBF1 GATA3 CREB1 FOS MIR4661 GC08P091158
GH08H091179 0.9 Ensembl ENCODE 0.3 -25.0 -25031 1.3 ZNF639 JUN MAX ZNF175 CEBPB CEBPG EP300 FOSL1 ZNF589 JUND SLC26A7 LRRC69 GC08P091158 MIR4661
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR4661 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR4661 Gene

Genomic Locations for MIR4661 Gene
75 bases
Plus strand

Genomic View for MIR4661 Gene

Genes around MIR4661 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4661 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4661 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4661 Gene

Proteins for MIR4661 Gene

Post-translational modifications for MIR4661 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4661 Gene

Domains & Families for MIR4661 Gene

Gene Families for MIR4661 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4661: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4661 Gene

Function for MIR4661 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4661 Gene

Localization for MIR4661 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4661 Gene

Pathways & Interactions for MIR4661 Gene

SuperPathways for MIR4661 Gene

No Data Available

Interacting Proteins for MIR4661 Gene

Gene Ontology (GO) - Biological Process for MIR4661 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR4661 Gene

Drugs & Compounds for MIR4661 Gene

No Compound Related Data Available

Transcripts for MIR4661 Gene

mRNA/cDNA for MIR4661 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4661 Gene

No ASD Table

Relevant External Links for MIR4661 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR4661 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4661 Gene:

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4661 Gene

Orthologs for MIR4661 Gene

Evolution for MIR4661 Gene

Gene Tree for MIR4661 (if available)
Gene Tree for MIR4661 (if available)

No data available for Orthologs for MIR4661 Gene

Paralogs for MIR4661 Gene

No data available for Paralogs for MIR4661 Gene

Variants for MIR4661 Gene

Sequence variations from dbSNP and Humsavar for MIR4661 Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type
rs1001886056 -- 91,204,957(+) GTATA(A/C)CCTTT intron-variant, upstream-variant-2KB
rs1002339943 -- 91,205,240(+) AATAT(A/G)TGAGC intron-variant, upstream-variant-2KB
rs1002777766 -- 91,205,433(+) TGTCA(C/G)GTATT intron-variant, upstream-variant-2KB
rs1006054554 -- 91,204,443(+) AAACA(A/C)CTTAA intron-variant, upstream-variant-2KB
rs1006521175 -- 91,204,841(+) ACTAT(A/G)TGTGT intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR4661 Gene

Variant ID Type Subtype PubMed ID
esv3618017 CNV loss 21293372
esv35058 CNV loss 17911159
esv2759629 CNV loss 17122850

Relevant External Links for MIR4661 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4661 Gene

Disorders for MIR4661 Gene

Relevant External Links for MIR4661

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR4661 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4661 Gene

Publications for MIR4661 Gene

  1. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H … Rovira C (Cancer research 2011) 3 60
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 60

Products for MIR4661 Gene

Sources for MIR4661 Gene

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