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Aliases for MIR4660 Gene

Subcategory (RNA class) for MIR4660 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4660 Gene

  • MicroRNA 4660 2 3 5
  • Hsa-Mir-4660 3

External Ids for MIR4660 Gene

Previous GeneCards Identifiers for MIR4660 Gene

  • GC08U901563
  • GC08P008907

Summaries for MIR4660 Gene

Entrez Gene Summary for MIR4660 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4660 Gene

MIR4660 (MicroRNA 4660) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4660 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4660 Gene

Genomics for MIR4660 Gene

Regulatory Elements for MIR4660 Gene

Enhancers for MIR4660 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH08H009056 1.6 FANTOM5 Ensembl ENCODE dbSUPER 0.4 +9.2 9176 2 PKNOX1 KLF1 MAX ZNF76 ZIC2 GLIS2 CTBP1 ZNF316 ZBTB48 ZNF600 FAM86B3P ERI1 RPL10P19 MIR4660 RNU7-55P
GH08H009065 1.5 Ensembl ENCODE dbSUPER 0.4 +17.9 17924 1 HDGF FEZF1 YBX1 ZNF2 GATA2 ZNF143 KLF7 RUNX3 REST ZNF592 ERI1 RPL10P19 RNU7-55P MIR4660
GH08H009039 1 Ensembl ENCODE 0.4 -7.4 -7430 2 PKNOX1 EBF1 BATF RELA POLR2A RUNX3 IKZF2 JUNB TRIM22 DPF2 ERI1 ENSG00000254340 ENSG00000253426 PPP1R3B RNU7-55P MFHAS1 MIR4660 LOC105379227
GH08H009010 1.3 Ensembl ENCODE 0.3 -35.4 -35430 5 PKNOX1 ATF1 ARNT FEZF1 TCF12 GTF3C2 ZNF766 GATA2 ZNF207 FOS ERI1 RPL10P19 ENSG00000272267 LOC105379227 MIR4660
GH08H009005 1.1 Ensembl ENCODE 0.3 -41.6 -41646 2 HDAC1 PKNOX1 ARNT FOS IKZF2 CEBPB ZEB2 TFDP1 ZNF589 SMARCA4 ERI1 MFHAS1 RNU6-682P LOC105379227 MIR4660
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR4660 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR4660 Gene

Chromosome:
8
Start:
9,048,445 bp from pter
End:
9,048,518 bp from pter
Size:
74 bases
Orientation:
Plus strand

Genomic View for MIR4660 Gene

Genes around MIR4660 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4660 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4660 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4660 Gene

Proteins for MIR4660 Gene

Post-translational modifications for MIR4660 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4660 Gene

Domains & Families for MIR4660 Gene

Gene Families for MIR4660 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4660: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4660 Gene

Function for MIR4660 Gene

Phenotypes From GWAS Catalog for MIR4660 Gene

Animal Model Products

CRISPR Products

miRNA Products

Clone Products

  • Applied Biological Materials Clones for MIR4660
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4660 Gene

Localization for MIR4660 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4660 Gene

Pathways & Interactions for MIR4660 Gene

SuperPathways for MIR4660 Gene

No Data Available

Interacting Proteins for MIR4660 Gene

Gene Ontology (GO) - Biological Process for MIR4660 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4660 Gene

Drugs & Compounds for MIR4660 Gene

No Compound Related Data Available

Transcripts for MIR4660 Gene

mRNA/cDNA for MIR4660 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

miRNA Products

Clone Products

  • Applied Biological Materials Clones for MIR4660
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4660 Gene

No ASD Table

Relevant External Links for MIR4660 Gene

GeneLoc Exon Structure for
MIR4660
ECgene alternative splicing isoforms for
MIR4660

Expression for MIR4660 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR4660 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4660 Gene:

MIR4660
genes like me logo Genes that share expression patterns with MIR4660: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4660 Gene

Orthologs for MIR4660 Gene

Evolution for MIR4660 Gene

ENSEMBL:
Gene Tree for MIR4660 (if available)
TreeFam:
Gene Tree for MIR4660 (if available)

No data available for Orthologs for MIR4660 Gene

Paralogs for MIR4660 Gene

No data available for Paralogs for MIR4660 Gene

Variants for MIR4660 Gene

Sequence variations from dbSNP and Humsavar for MIR4660 Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type
rs1000088594 -- 9,047,581(+) GCAGT(C/T)CCAGC intron-variant, upstream-variant-2KB
rs1002303557 -- 9,048,764(+) CTCAG(C/G)TTCCT intron-variant, downstream-variant-500B
rs1002308365 -- 9,046,632(+) ACTTT(C/G)TCCCC intron-variant, upstream-variant-2KB
rs1002379064 -- 9,046,794(+) GAAAG(C/T)AGTGG intron-variant, upstream-variant-2KB
rs1003310180 -- 9,047,691(+) GAGAC(A/C)CTGTC intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR4660 Gene

Variant ID Type Subtype PubMed ID
esv3616157 CNV loss 21293372
esv3616162 CNV loss 21293372
nsv831229 CNV gain+loss 17160897

Relevant External Links for MIR4660 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4660

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4660 Gene

Disorders for MIR4660 Gene

Relevant External Links for MIR4660

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR4660

No disorders were found for MIR4660 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4660 Gene

Publications for MIR4660 Gene

  1. Genome-wide association study identifies three novel susceptibility loci for severe Acne vulgaris. (PMID: 24927181) Navarini AA … Barker JN (Nature communications 2014) 3 60
  2. A genome-wide association study provides evidence for association of chromosome 8p23 (MYP10) and 10q21.1 (MYP15) with high myopia in the French Population. (PMID: 23049088) Meng W … Malecaze F (Investigative ophthalmology & visual science 2012) 3 60
  3. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H … Rovira C (Cancer research 2011) 3 60
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 60

Products for MIR4660 Gene

Sources for MIR4660 Gene

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