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Aliases for MIR4660 Gene

Subcategory (RNA class) for MIR4660 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4660 Gene

  • MicroRNA 4660 2 3
  • Hsa-Mir-4660 3

External Ids for MIR4660 Gene

Previous GeneCards Identifiers for MIR4660 Gene

  • GC08U901563
  • GC08P008907

Summaries for MIR4660 Gene

Entrez Gene Summary for MIR4660 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4660 Gene

MIR4660 (MicroRNA 4660) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4660 Gene

Genomics for MIR4660 Gene

Genomic Location for MIR4660 Gene

Start:
9,048,445 bp from pter
End:
9,048,518 bp from pter
Size:
74 bases
Orientation:
Plus strand

Genomic View for MIR4660 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR4660 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4660 Gene

No data available for Regulatory Elements for MIR4660 Gene

Proteins for MIR4660 Gene

Post-translational modifications for MIR4660 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4660 Gene

Domains for MIR4660 Gene

Gene Families for MIR4660 Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4660: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4660 Gene

Function for MIR4660 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR4660 Gene

Localization for MIR4660 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4660 Gene

Pathways for MIR4660 Gene

SuperPathways for MIR4660 Gene

No Data Available

Interacting Proteins for MIR4660 Gene

Gene Ontology (GO) - Biological Process for MIR4660 Gene

None

No data available for Pathways by source for MIR4660 Gene

Transcripts for MIR4660 Gene

mRNA/cDNA for MIR4660 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4660 Gene

No ASD Table

Relevant External Links for MIR4660 Gene

GeneLoc Exon Structure for
MIR4660
ECgene alternative splicing isoforms for
MIR4660

Expression for MIR4660 Gene

mRNA expression in normal human tissues for MIR4660 Gene

genes like me logo Genes that share expressions with MIR4660: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for MIR4660 Gene

Orthologs for MIR4660 Gene

Evolution for MIR4660 Gene

ENSEMBL:
Gene Tree for MIR4660 (if available)
TreeFam:
Gene Tree for MIR4660 (if available)

No data available for Orthologs for MIR4660 Gene

Paralogs for MIR4660 Gene

No data available for Paralogs for MIR4660 Gene

Variants for MIR4660 Gene

Sequence variations from dbSNP and Humsavar for MIR4660 Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type MAF
rs2044386 -- 9,046,679(+) AAAAG(C/T)AAAAA upstream-variant-2KB
rs2921379 -- 9,048,416(-) GGACG(C/T)TTTTT upstream-variant-2KB
rs4841089 -- 9,047,522(+) aaaaa(A/G)ttttt upstream-variant-2KB
rs6983877 -- 9,047,129(+) TGCCC(C/T)GACCA upstream-variant-2KB
rs7816149 -- 9,047,759(+) CCAAC(A/G)GAGCA upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR4660 Gene

Variant ID Type Subtype PubMed ID
nsv890331 CNV Loss 21882294
nsv831229 CNV Gain+Loss 17160897

Relevant External Links for MIR4660 Gene

HapMap Linkage Disequilibrium report
MIR4660

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MIR4660 Gene

Disorders for MIR4660 Gene

No disorders were found for MIR4660 Gene.

No data available for UniProtKB/Swiss-Prot for MIR4660 Gene

Publications for MIR4660 Gene

  1. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  2. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H. … Rovira C. (Cancer Res. 2011) 3
  3. A genome-wide association study provides evidence for association of chromosome 8p23 (MYP10) and 10q21.1 (MYP15) with high myopia in the French Population. (PMID: 23049088) Meng W. … Malecaze F. (Invest. Ophthalmol. Vis. Sci. 2012) 3
  4. Genome-wide association study identifies three novel susceptibility loci for severe Acne vulgaris. (PMID: 24927181) Navarini A.A. … Barker J.N. (Nat Commun 2014) 3

Products for MIR4660 Gene

Sources for MIR4660 Gene

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