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Aliases for MIR4656 Gene

Subcategory (RNA class) for MIR4656 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR4656 Gene

  • MicroRNA 4656 2 3 5
  • Hsa-Mir-4656 3

External Ids for MIR4656 Gene

Previous GeneCards Identifiers for MIR4656 Gene

  • GC07U903202
  • GC07M004830
  • GC07M004831
  • GC07M004833

Summaries for MIR4656 Gene

Entrez Gene Summary for MIR4656 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4656 Gene

MIR4656 (MicroRNA 4656) is an RNA Gene, and is affiliated with the miRNA class.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4656 Gene

Genomics for MIR4656 Gene

Regulatory Elements for MIR4656 Gene

Enhancers for MIR4656 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH07G004791 1.1 Ensembl ENCODE 0.7 -3.6 -3560 2.3 ATF1 SIN3A BMI1 ZBTB40 ELK1 ZNF143 ZNF207 FOS RCOR1 CREM AP5Z1 RADIL MIR4656 GC07P004807
GH07G004798 1 Ensembl ENCODE 0.4 -9.8 -9762 0.4 HDGF CTCF RB1 AGO1 ZSCAN4 MAX RAD21 POLR2A ZNF143 SMC3 AP5Z1 GC07P004807 MIR4656
GH07G004794 0.6 ENCODE 0.4 -6.1 -6117 0.9 CTCF STAT1 DDX20 NFYC FOS ZBTB33 AP5Z1 MIR4656 GC07P004807
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR4656 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR4656 Gene

Chromosome:
7
Start:
4,788,565 bp from pter
End:
4,788,639 bp from pter
Size:
75 bases
Orientation:
Minus strand

Genomic View for MIR4656 Gene

Genes around MIR4656 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4656 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4656 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4656 Gene

ORGUL Member Location for MIR4656 Gene

ORGUL Member Location for MIR4656 gene

Proteins for MIR4656 Gene

Post-translational modifications for MIR4656 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4656 Gene

Domains & Families for MIR4656 Gene

Gene Families for MIR4656 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4656: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4656 Gene

Function for MIR4656 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4656 Gene

Localization for MIR4656 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4656 Gene

Pathways & Interactions for MIR4656 Gene

SuperPathways for MIR4656 Gene

No Data Available

Interacting Proteins for MIR4656 Gene

Gene Ontology (GO) - Biological Process for MIR4656 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4656 Gene

Drugs & Compounds for MIR4656 Gene

No Compound Related Data Available

Transcripts for MIR4656 Gene

mRNA/cDNA for MIR4656 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4656 Gene

No ASD Table

Relevant External Links for MIR4656 Gene

GeneLoc Exon Structure for
MIR4656
ECgene alternative splicing isoforms for
MIR4656

Expression for MIR4656 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR4656 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4656 Gene:

MIR4656
genes like me logo Genes that share expression patterns with MIR4656: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4656 Gene

Orthologs for MIR4656 Gene

Evolution for MIR4656 Gene

ENSEMBL:
Gene Tree for MIR4656 (if available)
TreeFam:
Gene Tree for MIR4656 (if available)

No data available for Orthologs for MIR4656 Gene

Paralogs for MIR4656 Gene

No data available for Paralogs for MIR4656 Gene

Variants for MIR4656 Gene

Sequence variations from dbSNP and Humsavar for MIR4656 Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type
rs1057519342 Pathogenic 4,789,856(+) TCAAC(C/T)AGCTG nc-transcript-variant, upstream-variant-2KB, reference, stop-gained
rs118139547 Likely benign 4,789,818(+) TCCCA(C/T)TCCTG intron-variant, upstream-variant-2KB
rs3750012 Likely benign 4,788,962(-) CAGGC(A/G)GCGAG intron-variant, upstream-variant-2KB
rs77560694 Likely benign 4,788,253(+) CTTTT(C/T)CAATA nc-transcript-variant, downstream-variant-500B, reference, synonymous-codon
rs77890266 Likely benign 4,788,228(+) CTTCC(A/G)GGACC nc-transcript-variant, downstream-variant-500B, reference, missense

Structural Variations from Database of Genomic Variants (DGV) for MIR4656 Gene

Variant ID Type Subtype PubMed ID
esv2664593 CNV deletion 23128226
esv3611949 CNV loss 21293372
nsv1029123 CNV loss 25217958
nsv471293 CNV loss 18288195
nsv482101 CNV gain 20164927
nsv528748 CNV loss 19592680
nsv5626 CNV insertion 18451855
nsv605977 CNV loss 21841781
nsv605978 CNV gain 21841781
nsv8033 CNV loss 18304495
nsv823994 CNV gain 20364138
nsv950797 CNV deletion 24416366

Relevant External Links for MIR4656 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4656

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4656 Gene

Disorders for MIR4656 Gene

Relevant External Links for MIR4656

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR4656

No disorders were found for MIR4656 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4656 Gene

Publications for MIR4656 Gene

  1. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H. … Rovira C. (Cancer Res. 2011) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4656 Gene

Sources for MIR4656 Gene

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