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Aliases for MIR4655 Gene

Subcategory (RNA class) for MIR4655 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR4655 Gene

  • MicroRNA 4655 2 3 5
  • Hsa-Mir-4655 3

External Ids for MIR4655 Gene

Previous GeneCards Identifiers for MIR4655 Gene

  • GC07U903196
  • GC07M001886

Summaries for MIR4655 Gene

Entrez Gene Summary for MIR4655 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4655 Gene

MIR4655 (MicroRNA 4655) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4655 Gene

Genomics for MIR4655 Gene

Regulatory Elements for MIR4655 Gene

Enhancers for MIR4655 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH07F001841 1 ENCODE 0.8 +0.7 715 3.5 ATF1 ARNT ARID4B DMAP1 ZNF48 FOS MXD4 NCOA1 REST KAT8 LOC100127955 NUDT1 MRM2 TMEM184A IQCE GC07M001835 MIR4655
GH07F001852 1.5 FANTOM5 Ensembl ENCODE 0.4 -9.9 -9882 2.4 HDAC1 PKNOX1 CREB3L1 SIN3A KLF17 YY1 GATA2 SCRT2 FOS CREM LOC100127955 MIR4655 GC07M001848
GH07F001856 1 ENCODE 0.4 -12.3 -12327 0.2 HDGF ATF1 PKNOX1 ARNT CREB3L1 ELK1 GATA2 KLF13 NCOA1 REST MIR4655 GC07M001848
GH07F001881 1.2 Ensembl ENCODE 0.3 -38.8 -38756 2.4 HDAC1 ATF1 NFRKB PTRF SIN3A RAD21 YY1 ELK1 FOS MIER1 LOC100127955 MRM2 NUDT1 MAD1L1 EIF3B GC07M001848 MIR4655
GH07F001874 1.1 Ensembl ENCODE 0.3 -31.2 -31244 1.8 ELF3 HDAC1 KLF17 ARID4B THRB ZNF48 RAD21 RARA ZBTB2 SP5 NUDT1 MRM2 GC07M001848 MIR4655
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR4655 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR4655 Gene

Chromosome:
7
Start:
1,844,180 bp from pter
End:
1,844,253 bp from pter
Size:
74 bases
Orientation:
Minus strand

Genomic View for MIR4655 Gene

Genes around MIR4655 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4655 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4655 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4655 Gene

ORGUL Member Location for MIR4655 Gene

ORGUL Member Location for MIR4655 gene

Proteins for MIR4655 Gene

Post-translational modifications for MIR4655 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4655 Gene

Domains & Families for MIR4655 Gene

Gene Families for MIR4655 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4655: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4655 Gene

Function for MIR4655 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4655 Gene

Localization for MIR4655 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4655 Gene

Pathways & Interactions for MIR4655 Gene

SuperPathways for MIR4655 Gene

No Data Available

Interacting Proteins for MIR4655 Gene

Gene Ontology (GO) - Biological Process for MIR4655 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4655 Gene

Transcripts for MIR4655 Gene

mRNA/cDNA for MIR4655 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4655 Gene

No ASD Table

Relevant External Links for MIR4655 Gene

GeneLoc Exon Structure for
MIR4655
ECgene alternative splicing isoforms for
MIR4655

Expression for MIR4655 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4655 Gene:

MIR4655
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR4655 Gene

Orthologs for MIR4655 Gene

Evolution for MIR4655 Gene

ENSEMBL:
Gene Tree for MIR4655 (if available)
TreeFam:
Gene Tree for MIR4655 (if available)

No data available for Orthologs for MIR4655 Gene

Paralogs for MIR4655 Gene

No data available for Paralogs for MIR4655 Gene

Variants for MIR4655 Gene

Sequence variations from dbSNP and Humsavar for MIR4655 Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type
rs10233560 -- 1,845,779(+) GGAGA(C/T)GGACA intron-variant, upstream-variant-2KB
rs10240761 -- 1,845,550(+) GTCCG(A/G)CTCTG intron-variant, upstream-variant-2KB
rs10240763 -- 1,845,556(+) CTCTG(A/G)TTCAC intron-variant, upstream-variant-2KB
rs10271073 -- 1,845,548(+) GCGTC(C/G/T)GGCTC intron-variant, upstream-variant-2KB
rs10271083 -- 1,845,561(+) GTTCA(C/T)GGGGA intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR4655 Gene

Variant ID Type Subtype PubMed ID
nsv1017814 CNV gain 25217958
nsv1030397 CNV gain 25217958
nsv471193 CNV loss 18288195
nsv509186 CNV insertion 20534489
nsv5616 CNV deletion 18451855
nsv605833 CNV loss 21841781
nsv830883 CNV loss 17160897
nsv950788 CNV deletion 24416366

Relevant External Links for MIR4655 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4655

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4655 Gene

Disorders for MIR4655 Gene

Relevant External Links for MIR4655

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR4655

No disorders were found for MIR4655 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4655 Gene

Publications for MIR4655 Gene

  1. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H. … Rovira C. (Cancer Res. 2011) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4655 Gene

Sources for MIR4655 Gene

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