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Aliases for MIR4654 Gene

Subcategory (RNA class) for MIR4654 Gene


Quality Score for this RNA gene is


Aliases for MIR4654 Gene

  • MicroRNA 4654 2 3 5
  • Hsa-Mir-4654 3
  • Mir-4654 3

External Ids for MIR4654 Gene

Previous GeneCards Identifiers for MIR4654 Gene

  • GC01U903276

Summaries for MIR4654 Gene

Entrez Gene Summary for MIR4654 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4654 Gene

MIR4654 (MicroRNA 4654) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4654 Gene

Genomics for MIR4654 Gene

Regulatory Elements for MIR4654 Gene

Enhancers for MIR4654 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01F162151 1.2 Ensembl ENCODE 0.8 -4.6 -4641 1.5 ATF1 MLX ARID4B SIN3A FEZF1 YY1 GLIS2 FOS ZNF263 ZHX2 C1orf226 SPATA46 MIR4654 GC01M162031
GH01F162156 0.2 ENCODE 0.8 +0.4 436 1.2 ZNF664 ZNF146 SMARCA4 CEBPA PRDM10 C1orf226 MIR4654 LOC105371475
GH01F162159 0.7 ENCODE 0.8 +2.6 2579 0.2 KLF1 ZNF211 PKNOX1 ZNF792 RAD21 E2F1 GATA3 CTBP1 PRDM10 RCOR1 SPATA46 C1orf226 MIR4654 LOC105371475
GH01F162147 0.6 ENCODE 0.4 -9.2 -9161 1.1 OSR2 BCL11A ZNF341 TEAD4 ZNF223 BCL6 THRB TCF7L2 C1orf226 SPATA46 MIR4654 GC01M162031
GH01F162162 0.4 ENCODE 0.4 +5.9 5883 0.3 C1orf226 SPATA46 MIR4654 LOC105371475
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around MIR4654 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR4654 Gene

162,157,107 bp from pter
162,157,182 bp from pter
76 bases
Plus strand

Genomic View for MIR4654 Gene

Genes around MIR4654 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4654 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4654 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4654 Gene

Proteins for MIR4654 Gene

Post-translational modifications for MIR4654 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4654 Gene

Domains & Families for MIR4654 Gene

Gene Families for MIR4654 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4654: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4654 Gene

Function for MIR4654 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4654 Gene

Localization for MIR4654 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4654 Gene

Pathways & Interactions for MIR4654 Gene

SuperPathways for MIR4654 Gene

No Data Available

Interacting Proteins for MIR4654 Gene

Gene Ontology (GO) - Biological Process for MIR4654 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR4654 Gene

Transcripts for MIR4654 Gene

mRNA/cDNA for MIR4654 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4654 Gene

No ASD Table

Relevant External Links for MIR4654 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR4654 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR4654 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4654 Gene:

genes like me logo Genes that share expression patterns with MIR4654: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR4654 Gene

Orthologs for MIR4654 Gene

Evolution for MIR4654 Gene

Gene Tree for MIR4654 (if available)
Gene Tree for MIR4654 (if available)

No data available for Orthologs for MIR4654 Gene

Paralogs for MIR4654 Gene

No data available for Paralogs for MIR4654 Gene

Variants for MIR4654 Gene

Sequence variations from dbSNP and Humsavar for MIR4654 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs10800329 -- 162,155,568(+) GTAAG(C/T)GCATT intron-variant, upstream-variant-2KB
rs112019574 -- 162,155,237(+) ATATA(C/T)ATATA intron-variant, upstream-variant-2KB
rs112442951 -- 162,155,232(+) TATAT(-/ATATAC)ATATA intron-variant, upstream-variant-2KB
rs112773752 -- 162,155,384(+) GAGCT(C/T)ATATA intron-variant, upstream-variant-2KB
rs113460832 -- 162,157,338(+) ATTAA(C/T)AGCAA intron-variant, downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for MIR4654 Gene

Variant ID Type Subtype PubMed ID
esv2758973 CNV gain 17122850
esv34209 CNV gain 17911159
esv3587740 CNV gain 21293372
esv3587741 CNV gain 21293372
nsv516482 CNV gain+loss 19592680
nsv818511 CNV gain 17921354
nsv831759 CNV gain+loss 17160897

Relevant External Links for MIR4654 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4654 Gene

Disorders for MIR4654 Gene

Relevant External Links for MIR4654

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR4654 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4654 Gene

Publications for MIR4654 Gene

  1. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A. … Griffiths-Jones S. (Nucleic Acids Res. 2011) 3 64
  2. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H. … Rovira C. (Cancer Res. 2011) 3 64
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4654 Gene

Sources for MIR4654 Gene

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