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Aliases for MIR4654 Gene

Subcategory (RNA class) for MIR4654 Gene


Quality Score for this RNA gene is


Aliases for MIR4654 Gene

  • MicroRNA 4654 2 3 5
  • Hsa-Mir-4654 3
  • Mir-4654 3

External Ids for MIR4654 Gene

Previous GeneCards Identifiers for MIR4654 Gene

  • GC01U903276

Summaries for MIR4654 Gene

Entrez Gene Summary for MIR4654 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4654 Gene

MIR4654 (MicroRNA 4654) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4654 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4654 Gene

Genomics for MIR4654 Gene

Regulatory Elements for MIR4654 Gene

Enhancers for MIR4654 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01H162151 1.3 ENCODE dbSUPER 0.7 -4.6 -4641 1.5 FOXA2 ATF1 MLX ARID4B SIN3A FEZF1 YY1 GLIS2 FOS ATF7 USP21 PPOX C1orf226 B4GALT3 ATF6 DUSP12 LOC148430 SPATA46 MIR4654 GC01M162031
GH01H162159 1.1 ENCODE dbSUPER 0.7 +2.6 2579 0.2 PKNOX1 ESRRA KLF1 ZNF211 NFIB ZNF792 BMI1 E2F1 CTBP1 GATA3 PPOX SPATA46 C1orf226 MIR4654 LOC105371475
GH01H162136 1.4 Ensembl ENCODE dbSUPER 0.4 -19.9 -19912 1.7 TBP RAD21 RARA RFX5 RCOR1 FOS DEK SMARCC1 CEBPB PPARG C1orf226 MIR4654 GC01M162031
GH01H162143 1.2 ENCODE dbSUPER 0.4 -11.9 -11910 3 ELF3 ZFP64 ARID4B FEZF1 RAD21 RARA ZNF121 GLIS2 THAP11 CEBPB C1orf226 SPATA46 MIR4654 GC01M162031
GH01H162167 1 ENCODE dbSUPER 0.4 +11.6 11590 2.5 NFIB SIN3A FEZF1 RAD21 CTBP1 GATA3 ZNF366 ZBTB48 SCRT2 ZNF600 LOC105371475 MIR4654
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR4654 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR4654 Gene

Genomic Locations for MIR4654 Gene
76 bases
Plus strand

Genomic View for MIR4654 Gene

Genes around MIR4654 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4654 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4654 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4654 Gene

Proteins for MIR4654 Gene

Post-translational modifications for MIR4654 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4654 Gene

Domains & Families for MIR4654 Gene

Gene Families for MIR4654 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4654: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4654 Gene

Function for MIR4654 Gene

Phenotypes From GWAS Catalog for MIR4654 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4654 Gene

Localization for MIR4654 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4654 Gene

Pathways & Interactions for MIR4654 Gene

SuperPathways for MIR4654 Gene

No Data Available

Interacting Proteins for MIR4654 Gene

Gene Ontology (GO) - Biological Process for MIR4654 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR4654 Gene

Drugs & Compounds for MIR4654 Gene

No Compound Related Data Available

Transcripts for MIR4654 Gene

mRNA/cDNA for MIR4654 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4654 Gene

No ASD Table

Relevant External Links for MIR4654 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR4654 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR4654 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4654 Gene:

genes like me logo Genes that share expression patterns with MIR4654: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4654 Gene

Orthologs for MIR4654 Gene

Evolution for MIR4654 Gene

Gene Tree for MIR4654 (if available)
Gene Tree for MIR4654 (if available)

No data available for Orthologs for MIR4654 Gene

Paralogs for MIR4654 Gene

No data available for Paralogs for MIR4654 Gene

Variants for MIR4654 Gene

Sequence variations from dbSNP and Humsavar for MIR4654 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs1000035194 -- 162,155,988(+) TTTCA(A/G)CCAGT intron-variant, upstream-variant-2KB
rs1001704176 -- 162,157,680(+) CCTGT(C/G)TAGAG intron-variant, downstream-variant-500B
rs1004293639 -- 162,155,559(+) TCCGG(A/G)AGTGT intron-variant, upstream-variant-2KB
rs1006251465 -- 162,156,908(+) GGACC(A/G)TGCTG intron-variant, upstream-variant-2KB
rs1007785445 -- 162,156,947(+) TTGTG(A/G)CCCTA intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR4654 Gene

Variant ID Type Subtype PubMed ID
nsv831759 CNV gain+loss 17160897
nsv818511 CNV gain 17921354
nsv516482 CNV gain+loss 19592680
esv3587741 CNV gain 21293372
esv3587740 CNV gain 21293372
esv34209 CNV gain 17911159
esv2758973 CNV gain 17122850

Relevant External Links for MIR4654 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4654 Gene

Disorders for MIR4654 Gene

Relevant External Links for MIR4654

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR4654 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4654 Gene

Publications for MIR4654 Gene

  1. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3 60
  2. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H … Rovira C (Cancer research 2011) 3 60
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 60

Products for MIR4654 Gene

Sources for MIR4654 Gene

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