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Aliases for MIR4651 Gene

Subcategory (RNA class) for MIR4651 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4651 Gene

  • MicroRNA 4651 2 3 5
  • Hsa-Mir-4651 3
  • Mir-4651 3

External Ids for MIR4651 Gene

Previous GeneCards Identifiers for MIR4651 Gene

  • GC07U903198
  • GC07P075547

Summaries for MIR4651 Gene

Entrez Gene Summary for MIR4651 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4651 Gene

MIR4651 (MicroRNA 4651) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are Metabolism and Cytochrome P450 - arranged by substrate type.

Additional gene information for MIR4651 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4651 Gene

Genomics for MIR4651 Gene

GeneHancer (GH) Regulatory Elements for MIR4651 Gene

Promoters and enhancers for MIR4651 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH07I075913 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 0.8 +3.6 3562 9.5 CLOCK MLX DMAP1 IRF4 YY1 ZNF143 SP3 SSRP1 GLIS1 RCOR2 POR RHBDD2 PMS2P3 STAG3L1 SNORA14A NSUN5P1 GTF2IRD2B LOC100133091 CCL26 ZP3
GH07I075905 Enhancer 1.2 Ensembl ENCODE 0.4 -8.5 -8502 3 PKNOX1 FOXA2 MLX ARID4B SIN3A DMAP1 YY1 SLC30A9 ZNF766 FOS PMS2P3 STAG3L1 SNORA14A CCL26 CCL24 GTF2IRD2B POMZP3 NSUN5P1 SRRM3 UPK3B
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR4651 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR4651 Gene

Genomic Locations for MIR4651 Gene
chr7:75,915,197-75,915,269
(GRCh38/hg38)
Size:
73 bases
Orientation:
Plus strand
chr7:75,544,515-75,544,587
(GRCh37/hg19)

Genomic View for MIR4651 Gene

Genes around MIR4651 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4651 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4651 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4651 Gene

Proteins for MIR4651 Gene

Post-translational modifications for MIR4651 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4651 Gene

Domains & Families for MIR4651 Gene

Gene Families for MIR4651 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4651: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4651 Gene

Function for MIR4651 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4651 Gene

Localization for MIR4651 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4651 Gene

Pathways & Interactions for MIR4651 Gene

genes like me logo Genes that share pathways with MIR4651: view

Pathways by source for MIR4651 Gene

Interacting Proteins for MIR4651 Gene

Gene Ontology (GO) - Biological Process for MIR4651 Gene

None

No data available for SIGNOR curated interactions for MIR4651 Gene

Drugs & Compounds for MIR4651 Gene

No Compound Related Data Available

Transcripts for MIR4651 Gene

mRNA/cDNA for MIR4651 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4651 Gene

No ASD Table

Relevant External Links for MIR4651 Gene

GeneLoc Exon Structure for
MIR4651
ECgene alternative splicing isoforms for
MIR4651

Expression for MIR4651 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR4651 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4651 Gene:

MIR4651
genes like me logo Genes that share expression patterns with MIR4651: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4651 Gene

Orthologs for MIR4651 Gene

Evolution for MIR4651 Gene

ENSEMBL:
Gene Tree for MIR4651 (if available)
TreeFam:
Gene Tree for MIR4651 (if available)

No data available for Orthologs for MIR4651 Gene

Paralogs for MIR4651 Gene

No data available for Paralogs for MIR4651 Gene

Variants for MIR4651 Gene

Sequence variations from dbSNP and Humsavar for MIR4651 Gene

SNP ID Clin Chr 07 pos Variation AA Info Type
rs3823884 benign, Antley-Bixler syndrome with genital anomalies and disordered steroidogenesis 75,915,137(+) A/C upstream_transcript_variant
rs72553977 uncertain-significance, Antley-Bixler syndrome with genital anomalies and disordered steroidogenesis 75,915,151(+) G/A/T upstream_transcript_variant
rs979631248 uncertain-significance, Antley-Bixler syndrome with genital anomalies and disordered steroidogenesis 75,915,179(+) G/A/C/T upstream_transcript_variant
rs996238133 uncertain-significance, Antley-Bixler syndrome with genital anomalies and disordered steroidogenesis 75,915,104(+) A/C upstream_transcript_variant
rs1003828367 -- 75,914,571(+) A/G upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR4651 Gene

Variant ID Type Subtype PubMed ID
dgv120n16 CNV deletion 17901297
esv3571928 CNV loss 25503493
esv3613742 CNV loss 21293372
nsv528969 CNV gain 19592680

Additional Variant Information for MIR4651 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4651

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4651 Gene

Disorders for MIR4651 Gene

Additional Disease Information for MIR4651

No disorders were found for MIR4651 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4651 Gene

Publications for MIR4651 Gene

  1. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3 58
  2. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H … Rovira C (Cancer research 2011) 3 58
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR4651 Gene

Sources for MIR4651 Gene

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