Free for academic non-profit institutions. Other users need a Commercial license

Aliases for MIR4651 Gene

Subcategory (RNA class) for MIR4651 Gene


Quality Score for this RNA gene is


Aliases for MIR4651 Gene

  • MicroRNA 4651 2 3 5
  • Hsa-Mir-4651 3
  • Mir-4651 3

External Ids for MIR4651 Gene

Previous GeneCards Identifiers for MIR4651 Gene

  • GC07U903198
  • GC07P075547

Summaries for MIR4651 Gene

Entrez Gene Summary for MIR4651 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4651 Gene

MIR4651 (MicroRNA 4651) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR4651 include Disordered Steroidogenesis Due To Cytochrome P450 Oxidoreductase and Antley-Bixler Syndrome With Genital Anomalies And Disordered Steroidogenesis. Among its related pathways are Cytochrome P450 - arranged by substrate type and Metabolism.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4651 Gene

Genomics for MIR4651 Gene

Regulatory Elements for MIR4651 Gene

Enhancers for MIR4651 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH07G075913 1.4 ENCODE dbSUPER 0.7 +3.6 3563 9.5 MLX CREB3L1 DMAP1 YY1 ZNF143 SP3 SSRP1 GLIS1 RCOR2 NBN LOC100133091 RHBDD2 SNORA14A CCL26 POR ZP3 MIR4651 RPL7L1P3
GH07G075905 1.3 Ensembl ENCODE 0.4 -8.5 -8503 3.0 FOXA2 PKNOX1 MLX ARID4B SIN3A DMAP1 YY1 SLC30A9 ZNF766 FOS SNORA14A CCL26 CCL24 SRRM3 UPK3B ZP3 MIR4651 POR
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR4651 on UCSC Golden Path with GeneCards custom track

Promoters for MIR4651 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

Genomic Location for MIR4651 Gene

75,915,197 bp from pter
75,915,269 bp from pter
73 bases
Plus strand

Genomic View for MIR4651 Gene

Genes around MIR4651 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4651 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4651 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4651 Gene

Proteins for MIR4651 Gene

Post-translational modifications for MIR4651 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4651 Gene

Domains & Families for MIR4651 Gene

Gene Families for MIR4651 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4651: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4651 Gene

Function for MIR4651 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4651 Gene

Localization for MIR4651 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4651 Gene

Pathways & Interactions for MIR4651 Gene

genes like me logo Genes that share pathways with MIR4651: view

Pathways by source for MIR4651 Gene

Interacting Proteins for MIR4651 Gene

Gene Ontology (GO) - Biological Process for MIR4651 Gene


No data available for SIGNOR curated interactions for MIR4651 Gene

Drugs & Compounds for MIR4651 Gene

No Compound Related Data Available

Transcripts for MIR4651 Gene

mRNA/cDNA for MIR4651 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4651 Gene

No ASD Table

Relevant External Links for MIR4651 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR4651 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR4651 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4651 Gene:

genes like me logo Genes that share expression patterns with MIR4651: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4651 Gene

Orthologs for MIR4651 Gene

Evolution for MIR4651 Gene

Gene Tree for MIR4651 (if available)
Gene Tree for MIR4651 (if available)

No data available for Orthologs for MIR4651 Gene

Paralogs for MIR4651 Gene

No data available for Paralogs for MIR4651 Gene

Variants for MIR4651 Gene

Sequence variations from dbSNP and Humsavar for MIR4651 Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type
rs886062437 Uncertain significance 75,915,104(+) GGCGA(A/C)GGCGG upstream-variant-2KB, utr-variant-5-prime
rs886062438 Uncertain significance 75,915,179(+) CCAGC(A/C/G/T)GTGAG upstream-variant-2KB, utr-variant-5-prime
rs3823884 Benign 75,915,137(-) AGGGC(G/T)CAGGC upstream-variant-2KB, utr-variant-5-prime
rs1003828367 -- 75,914,571(+) AGTTG(A/G)AGGCT upstream-variant-2KB
rs1004868048 -- 75,914,273(+) TGTAT(C/G)CCCCC upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR4651 Gene

Variant ID Type Subtype PubMed ID
dgv120n16 CNV deletion 17901297
esv3571928 CNV loss 25503493
esv3613742 CNV loss 21293372
nsv528969 CNV gain 19592680

Relevant External Links for MIR4651 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4651 Gene

Disorders for MIR4651 Gene

MalaCards: The human disease database

(3) MalaCards diseases for MIR4651 Gene - From: GeneCards

Disorder Aliases PubMed IDs
disordered steroidogenesis due to cytochrome p450 oxidoreductase
  • congenital adrenal hyperplasia due to cytochrome p450 oxidoreductase deficiency
antley-bixler syndrome with genital anomalies and disordered steroidogenesis
  • antley-bixler syndrome, with genital anomalies and disordered steroidogenesis
cytochrome p450 oxidoreductase deficiency
  • antley-bixler syndrome
- elite association - COSMIC cancer census association via MalaCards

Relevant External Links for MIR4651

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with MIR4651: view

No data available for UniProtKB/Swiss-Prot and Genatlas for MIR4651 Gene

Publications for MIR4651 Gene

  1. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A. … Griffiths-Jones S. (Nucleic Acids Res. 2011) 3 64
  2. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H. … Rovira C. (Cancer Res. 2011) 3 64
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4651 Gene

Sources for MIR4651 Gene

Loading form....