Subcategory (RNA class) for MIR4651 Gene
Quality Score for this RNA gene is
Aliases for MIR4651 Gene
External Ids for MIR4651 Gene
Previous GeneCards Identifiers for MIR4651 Gene
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
GeneCards Summary for MIR4651 Gene
MIR4651 (MicroRNA 4651) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR4651 include Cytochrome P450 Oxidoreductase Deficiency and Antley-Bixler Syndrome With Genital Anomalies And Disordered Steroidogenesis. Among its related pathways are Metabolism and Cytochrome P450 - arranged by substrate type. An important paralog of this gene is NOS1.
UniProtKB/Swiss-Prot for MIR4651 Gene
This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5.