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Aliases for MIR4651 Gene

Subcategory (RNA class) for MIR4651 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4651 Gene

  • MicroRNA 4651 2 3 5
  • Hsa-Mir-4651 3
  • Mir-4651 3

External Ids for MIR4651 Gene

Previous GeneCards Identifiers for MIR4651 Gene

  • GC07U903198
  • GC07P075547

Summaries for MIR4651 Gene

Entrez Gene Summary for MIR4651 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4651 Gene

MIR4651 (MicroRNA 4651) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are Metabolism and Cytochrome P450 - arranged by substrate type.

Additional gene information for MIR4651 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4651 Gene

Genomics for MIR4651 Gene

Regulatory Elements for MIR4651 Gene

Enhancers for MIR4651 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH07H075913 1.4 ENCODE dbSUPER 0.7 +3.6 3563 9 HDGF PKNOX1 FOXA2 MLX ARNT ARID4B SIN3A DMAP1 ZNF2 YY1 LOC100133091 PMS2P3 STAG3L1 RHBDD2 SNORA14A NSUN5P1 GTF2IRD2B CCL26 POMZP3 POR
GH07H075905 1.3 Ensembl ENCODE 0.4 -8.5 -8503 2 PKNOX1 FOXA2 ATF1 MLX ARID4B SIN3A DMAP1 YY1 SLC30A9 ZNF766 PMS2P3 STAG3L1 SNORA14A CCL26 CCL24 GTF2IRD2B POMZP3 NSUN5P1 SRRM3 UPK3B
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR4651 on UCSC Golden Path with GeneCards custom track

Promoters for MIR4651 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000213831 203 2001 HDGF PKNOX1 FOXA2 MLX ARNT ARID4B SIN3A DMAP1 ZNF2 YY1

Genomic Location for MIR4651 Gene

Chromosome:
7
Start:
75,915,197 bp from pter
End:
75,915,269 bp from pter
Size:
73 bases
Orientation:
Plus strand

Genomic View for MIR4651 Gene

Genes around MIR4651 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4651 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4651 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4651 Gene

Proteins for MIR4651 Gene

Post-translational modifications for MIR4651 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4651 Gene

Domains & Families for MIR4651 Gene

Gene Families for MIR4651 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4651: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4651 Gene

Function for MIR4651 Gene

Animal Model Products

CRISPR Products

miRNA Products

Clone Products

  • Applied Biological Materials Clones for MIR4651
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4651 Gene

Localization for MIR4651 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4651 Gene

Pathways & Interactions for MIR4651 Gene

genes like me logo Genes that share pathways with MIR4651: view

Pathways by source for MIR4651 Gene

Interacting Proteins for MIR4651 Gene

Gene Ontology (GO) - Biological Process for MIR4651 Gene

None

No data available for SIGNOR curated interactions for MIR4651 Gene

Drugs & Compounds for MIR4651 Gene

No Compound Related Data Available

Transcripts for MIR4651 Gene

mRNA/cDNA for MIR4651 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

miRNA Products

Clone Products

  • Applied Biological Materials Clones for MIR4651
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4651 Gene

No ASD Table

Relevant External Links for MIR4651 Gene

GeneLoc Exon Structure for
MIR4651
ECgene alternative splicing isoforms for
MIR4651

Expression for MIR4651 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR4651 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4651 Gene:

MIR4651
genes like me logo Genes that share expression patterns with MIR4651: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4651 Gene

Orthologs for MIR4651 Gene

Evolution for MIR4651 Gene

ENSEMBL:
Gene Tree for MIR4651 (if available)
TreeFam:
Gene Tree for MIR4651 (if available)

No data available for Orthologs for MIR4651 Gene

Paralogs for MIR4651 Gene

No data available for Paralogs for MIR4651 Gene

Variants for MIR4651 Gene

Sequence variations from dbSNP and Humsavar for MIR4651 Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type
rs886062437 Uncertain significance 75,915,104(+) GGCGA(A/C)GGCGG upstream-variant-2KB, utr-variant-5-prime
rs886062438 Uncertain significance 75,915,179(+) CCAGC(A/C/G/T)GTGAG upstream-variant-2KB, utr-variant-5-prime
rs3823884 Benign 75,915,137(-) AGGGC(G/T)CAGGC upstream-variant-2KB, utr-variant-5-prime
rs1003828367 -- 75,914,571(+) AGTTG(A/G)AGGCT upstream-variant-2KB
rs1004868048 -- 75,914,273(+) TGTAT(C/G)CCCCC upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR4651 Gene

Variant ID Type Subtype PubMed ID
dgv120n16 CNV deletion 17901297
esv3571928 CNV loss 25503493
esv3613742 CNV loss 21293372
nsv528969 CNV gain 19592680

Relevant External Links for MIR4651 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4651

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4651 Gene

Disorders for MIR4651 Gene

Relevant External Links for MIR4651

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR4651

No disorders were found for MIR4651 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4651 Gene

Publications for MIR4651 Gene

  1. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3 60
  2. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H … Rovira C (Cancer research 2011) 3 60
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 60

Products for MIR4651 Gene

Sources for MIR4651 Gene

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