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Aliases for MIR4650-2 Gene

Subcategory (RNA class) for MIR4650-2 Gene


Quality Score for this RNA gene is


Aliases for MIR4650-2 Gene

  • MicroRNA 4650-2 2 3 5
  • Hsa-Mir-4650-2 3

External Ids for MIR4650-2 Gene

Previous GeneCards Identifiers for MIR4650-2 Gene

  • GC07U903201
  • GC07P072166

Summaries for MIR4650-2 Gene

Entrez Gene Summary for MIR4650-2 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4650-2 Gene

MIR4650-2 (MicroRNA 4650-2) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4650-2 Gene

Genomics for MIR4650-2 Gene

Regulatory Elements for MIR4650-2 Gene

Enhancers for MIR4650-2 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH07F072695 0.2 ENCODE 0.8 -1.5 -1464 2.8 CTCF PKNOX1 REST ELF1 ZNF316 ATF3 IKZF1 PBX2 NFE2 MLLT1 MIR4650-2 GC07P072675
GH07F072705 0.2 Ensembl 0.4 +8.2 8198 0.6 PKNOX1 PBX2 JUNB NFE2 MIR4650-2 ENSG00000270694
GH07F072690 0.2 ENCODE 0.4 -6.3 -6281 1.7 TYW1B MIR4650-2 GC07P072675
GH07F072689 1 ENCODE 0.4 -7.9 -7865 0.1 NR2F1 NR2C2 MIR4650-2 GC07P072675
GH07F072706 0.9 Ensembl 0.4 +7.6 7598 0.2 PKNOX1 PBX2 JUNB NFE2 MIR4650-2 ENSG00000270694
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around MIR4650-2 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR4650-2 Gene

72,697,903 bp from pter
72,697,978 bp from pter
76 bases
Plus strand

Genomic View for MIR4650-2 Gene

Genes around MIR4650-2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4650-2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4650-2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4650-2 Gene

Proteins for MIR4650-2 Gene

Post-translational modifications for MIR4650-2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4650-2 Gene

Domains & Families for MIR4650-2 Gene

Gene Families for MIR4650-2 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4650-2: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4650-2 Gene

Function for MIR4650-2 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4650-2 Gene

Localization for MIR4650-2 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4650-2 Gene

Pathways & Interactions for MIR4650-2 Gene

SuperPathways for MIR4650-2 Gene

No Data Available

Interacting Proteins for MIR4650-2 Gene

Gene Ontology (GO) - Biological Process for MIR4650-2 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR4650-2 Gene

Transcripts for MIR4650-2 Gene

mRNA/cDNA for MIR4650-2 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4650-2 Gene

No ASD Table

Relevant External Links for MIR4650-2 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR4650-2 Gene

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR4650-2 Gene

Orthologs for MIR4650-2 Gene

Evolution for MIR4650-2 Gene

Gene Tree for MIR4650-2 (if available)
Gene Tree for MIR4650-2 (if available)

No data available for Orthologs for MIR4650-2 Gene

Paralogs for MIR4650-2 Gene

No data available for Paralogs for MIR4650-2 Gene

Variants for MIR4650-2 Gene

Sequence variations from dbSNP and Humsavar for MIR4650-2 Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type
rs10279507 -- 72,696,062(+) cctgc(C/G)tcagt intron-variant, upstream-variant-2KB
rs113327433 -- 72,697,222(+) CCTTT(C/T)ACAAA intron-variant, upstream-variant-2KB
rs114494950 -- 72,698,201(+) ACCGA(A/G)CTGGC intron-variant, downstream-variant-500B
rs114947775 -- 72,697,399(+) GTCAA(A/G)GAGCA intron-variant, upstream-variant-2KB
rs115950551 -- 72,698,198(+) CTCAC(C/T)GAGCT intron-variant, downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for MIR4650-2 Gene

Variant ID Type Subtype PubMed ID
dgv1116n67 CNV gain 20364138
dgv11442n54 CNV gain 21841781
dgv11443n54 CNV gain 21841781
dgv1299e214 CNV gain 21293372
dgv1923e212 CNV gain 25503493
dgv231e55 CNV gain 17911159
dgv62n64 CNV gain 17921354
dgv6459n100 CNV loss 25217958
dgv6460n100 CNV gain 25217958
dgv6461n100 CNV gain 25217958
dgv6462n100 CNV gain 25217958
dgv6463n100 CNV gain 25217958
dgv821n27 CNV gain 19166990
esv2759535 CNV gain 17122850
esv2759537 CNV gain+loss 17122850
esv2761093 CNV loss 21179565
esv33871 CNV loss 17666407
esv34349 CNV gain 17911159
esv3613667 CNV loss 21293372
esv3613668 CNV gain 21293372
esv3891136 CNV gain 25118596
esv3891138 CNV gain 25118596
esv3891144 CNV gain 25118596
nsv1019945 CNV gain+loss 25217958
nsv1020209 CNV gain 25217958
nsv1146102 OTHER inversion 26484159
nsv1161562 CNV duplication 26073780
nsv436901 CNV insertion 17901297
nsv442053 CNV gain 18776908
nsv469716 CNV gain 16826518
nsv470310 CNV gain 18288195
nsv520573 CNV gain+loss 19592680
nsv5774 CNV insertion 18451855
nsv831019 CNV loss 17160897
nsv966838 CNV duplication 23825009
nsv970525 CNV duplication 23825009

Relevant External Links for MIR4650-2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4650-2 Gene

Disorders for MIR4650-2 Gene

Relevant External Links for MIR4650-2

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR4650-2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4650-2 Gene

Publications for MIR4650-2 Gene

  1. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H. … Rovira C. (Cancer Res. 2011) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4650-2 Gene

Sources for MIR4650-2 Gene

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