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Aliases for MIR4650-1 Gene

Subcategory (RNA class) for MIR4650-1 Gene


Quality Score for this RNA gene is


Aliases for MIR4650-1 Gene

  • MicroRNA 4650-1 2 3 5
  • Hsa-Mir-4650-1 3

External Ids for MIR4650-1 Gene

Previous GeneCards Identifiers for MIR4650-1 Gene

  • GC07U903189
  • GC07M066579

Summaries for MIR4650-1 Gene

Entrez Gene Summary for MIR4650-1 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4650-1 Gene

MIR4650-1 (MicroRNA 4650-1) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4650-1 Gene

Genomics for MIR4650-1 Gene

Regulatory Elements for MIR4650-1 Gene

Enhancers for MIR4650-1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH07F067127 1.7 FANTOM5 Ensembl ENCODE 0.3 -15.0 -15037 3.3 HDGF PKNOX1 ARNT ARID4B SIN3A FEZF1 DMAP1 ZNF766 FOS SP5 TYW1 RABGEF1 ENSG00000229180 ENSG00000223473 STAG3L4 ENSG00000244657 LOC100420547 ENSG00000230189 GTF2IP23 ENSG00000232559
GH07F067114 0.6 Ensembl 0.8 -0.5 -505 0.2 ATF3 FOXK2 L3MBTL2 IKZF1 MLLT1 REST ELF1 RABGEF1 MIR4650-1 GC07P067259
GH07F067102 0.9 Ensembl ENCODE 0.4 +9.5 9503 3.8 HDAC1 PKNOX1 ESRRA RNF2 ARID1B HDAC2 NCOR1 IKZF1 HMBOX1 KDM1A TYW1 STAG3L4 RABGEF1 MIR4650-1 ENSG00000233383
GH07F067099 0.9 ENCODE 0.4 +13.5 13522 1.9 HDAC1 CBX3 ARNT FEZF1 ZNF263 ZBTB2 ZEB2 ZNF843 ZFP69B SMARCA4 TYW1 ENSG00000233383 MIR4650-1
GH07F067162 1.3 Ensembl ENCODE 0.2 -49.1 -49114 1.2 HDGF PKNOX1 ATF1 CREB3L1 ARID4B SIN3A DMAP1 ZNF48 YY1 GLIS2 TYW1 STAG3L4 ENSG00000232559 MIR4650-1 GC07P067259
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR4650-1 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR4650-1 Gene

67,114,322 bp from pter
67,114,397 bp from pter
76 bases
Minus strand

Genomic View for MIR4650-1 Gene

Genes around MIR4650-1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4650-1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4650-1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4650-1 Gene

ORGUL Member Location for MIR4650-1 Gene

ORGUL Member Location for MIR4650-1 gene

Proteins for MIR4650-1 Gene

Post-translational modifications for MIR4650-1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4650-1 Gene

Domains & Families for MIR4650-1 Gene

Gene Families for MIR4650-1 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4650-1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4650-1 Gene

Function for MIR4650-1 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4650-1 Gene

Localization for MIR4650-1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4650-1 Gene

Pathways & Interactions for MIR4650-1 Gene

SuperPathways for MIR4650-1 Gene

No Data Available

Interacting Proteins for MIR4650-1 Gene

Gene Ontology (GO) - Biological Process for MIR4650-1 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR4650-1 Gene

Transcripts for MIR4650-1 Gene

mRNA/cDNA for MIR4650-1 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4650-1 Gene

No ASD Table

Relevant External Links for MIR4650-1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR4650-1 Gene

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR4650-1 Gene

Orthologs for MIR4650-1 Gene

Evolution for MIR4650-1 Gene

Gene Tree for MIR4650-1 (if available)
Gene Tree for MIR4650-1 (if available)

No data available for Orthologs for MIR4650-1 Gene

Paralogs for MIR4650-1 Gene

No data available for Paralogs for MIR4650-1 Gene

Variants for MIR4650-1 Gene

Sequence variations from dbSNP and Humsavar for MIR4650-1 Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type
rs10579991 -- 67,114,824(+) GTCTC(-/TT)TGCTA intron-variant, upstream-variant-2KB
rs111534600 -- 67,114,096(+) GTGTG(A/C)CAGCT intron-variant, downstream-variant-500B
rs112416705 -- 67,114,935(+) GAGTG(C/T)AGCAT intron-variant, upstream-variant-2KB
rs112488021 -- 67,115,796(+) ATTGT(A/G)TGGCA intron-variant, upstream-variant-2KB
rs11769928 -- 67,116,098(+) aggtg(C/T)gtgga intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR4650-1 Gene

Variant ID Type Subtype PubMed ID
nsv970525 CNV duplication 23825009
nsv966838 CNV duplication 23825009
nsv831019 CNV loss 17160897
nsv5774 CNV insertion 18451855
nsv520573 CNV gain+loss 19592680
nsv470310 CNV gain 18288195
nsv469716 CNV gain 16826518
nsv442053 CNV gain 18776908
nsv436901 CNV insertion 17901297
nsv1161562 CNV duplication 26073780
nsv1146102 OTHER inversion 26484159
nsv1020209 CNV gain 25217958
nsv1019945 CNV gain+loss 25217958
esv3891144 CNV gain 25118596
esv3891138 CNV gain 25118596
esv3891136 CNV gain 25118596
esv3613668 CNV gain 21293372
esv3613667 CNV loss 21293372
esv34349 CNV gain 17911159
esv33871 CNV loss 17666407
esv2761093 CNV loss 21179565
esv2759537 CNV gain+loss 17122850
esv2759535 CNV gain 17122850
dgv821n27 CNV gain 19166990
dgv6463n100 CNV gain 25217958
dgv6462n100 CNV gain 25217958
dgv6461n100 CNV gain 25217958
dgv6460n100 CNV gain 25217958
dgv6459n100 CNV loss 25217958
dgv62n64 CNV gain 17921354
dgv231e55 CNV gain 17911159
dgv1923e212 CNV gain 25503493
dgv1299e214 CNV gain 21293372
dgv11443n54 CNV gain 21841781
dgv11442n54 CNV gain 21841781
dgv1116n67 CNV gain 20364138

Relevant External Links for MIR4650-1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4650-1 Gene

Disorders for MIR4650-1 Gene

Relevant External Links for MIR4650-1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR4650-1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4650-1 Gene

Publications for MIR4650-1 Gene

  1. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H. … Rovira C. (Cancer Res. 2011) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4650-1 Gene

Sources for MIR4650-1 Gene

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