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Aliases for MIR4648 Gene

Subcategory (RNA class) for MIR4648 Gene


Quality Score for this RNA gene is


Aliases for MIR4648 Gene

  • MicroRNA 4648 2 3 5
  • Hsa-Mir-4648 3

External Ids for MIR4648 Gene

Previous GeneCards Identifiers for MIR4648 Gene

  • GC07U903183
  • GC07P002570

Summaries for MIR4648 Gene

Entrez Gene Summary for MIR4648 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4648 Gene

MIR4648 (MicroRNA 4648) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4648 Gene

Genomics for MIR4648 Gene

Regulatory Elements for MIR4648 Gene

Enhancers for MIR4648 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH07F002520 1.2 FANTOM5 Ensembl ENCODE 0.8 -0.3 -298 13.2 HDGF PKNOX1 ARID4B SIN3A ZNF143 ZNF548 FOS ZNF263 SP5 ZHX2 LFNG CHST12 BRAT1 IQCE MIR4648
GH07F002519 0.5 ENCODE 0.4 -7.4 -7353 0.2 CREB3L1 SIN3A ZNF207 SP5 NFYC MXD4 REST KAT8 MBD2 KDM1A LFNG MIR4648
GH07F002521 1.1 ENCODE 0.4 -7.2 -7211 0.0 TBP CBX3 SREBF2 SIN3A RAD21 CREM SMARCA5 NFYA NFYC MXD4 MIR4648 LFNG
GH07F002515 0.6 ENCODE 0.4 -9.6 -9629 4.2 HDGF CREB3L1 ARID4B SIN3A YBX1 ZNF2 YY1 SLC30A9 ZNF143 ZNF207 LFNG MIR4648
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around MIR4648 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR4648 Gene

2,527,074 bp from pter
2,527,145 bp from pter
72 bases
Plus strand

Genomic View for MIR4648 Gene

Genes around MIR4648 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4648 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4648 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4648 Gene

Proteins for MIR4648 Gene

Post-translational modifications for MIR4648 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4648 Gene

Domains & Families for MIR4648 Gene

Gene Families for MIR4648 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4648: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4648 Gene

Function for MIR4648 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4648 Gene

Localization for MIR4648 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4648 Gene

Pathways & Interactions for MIR4648 Gene

SuperPathways for MIR4648 Gene

No Data Available

Interacting Proteins for MIR4648 Gene

Gene Ontology (GO) - Biological Process for MIR4648 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR4648 Gene

Transcripts for MIR4648 Gene

mRNA/cDNA for MIR4648 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4648 Gene

No ASD Table

Relevant External Links for MIR4648 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR4648 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR4648 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4648 Gene:

genes like me logo Genes that share expression patterns with MIR4648: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR4648 Gene

Orthologs for MIR4648 Gene

Evolution for MIR4648 Gene

Gene Tree for MIR4648 (if available)
Gene Tree for MIR4648 (if available)

No data available for Orthologs for MIR4648 Gene

Paralogs for MIR4648 Gene

No data available for Paralogs for MIR4648 Gene

Variants for MIR4648 Gene

Sequence variations from dbSNP and Humsavar for MIR4648 Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type
rs104894024 Pathogenic 2,525,301(+) CGCTT(A/C/T)ATCGA upstream-variant-2KB, reference, synonymous-codon, missense
rs147266260 Likely benign 2,525,444(+) AACTA(C/T)GTCAA upstream-variant-2KB, reference, synonymous-codon
rs151012354 Likely benign 2,525,504(+) GTCTA(C/T)GTCGG upstream-variant-2KB, reference, synonymous-codon
rs12700028 Benign 2,526,394(+) ACCTC(A/G)GAGCT upstream-variant-2KB, reference, synonymous-codon
rs13225716 Benign 2,526,799(+) ATGTC(A/G)GGCCC intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR4648 Gene

Variant ID Type Subtype PubMed ID
nsv471216 CNV loss 18288195
nsv605861 CNV loss 21841781
nsv605862 CNV loss 21841781
nsv823981 CNV gain 20364138
nsv830887 CNV loss 17160897
nsv950792 CNV deletion 24416366

Relevant External Links for MIR4648 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4648 Gene

Disorders for MIR4648 Gene

Relevant External Links for MIR4648

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR4648 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4648 Gene

Publications for MIR4648 Gene

  1. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H. … Rovira C. (Cancer Res. 2011) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4648 Gene

Sources for MIR4648 Gene

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