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MIR4648 Gene(RNA Gene)

MicroRNA 4648

GCID:
GC07P002528
GIFtS:
14
Genes Participants
UDN Logo

Aliases for MIR4648 Gene

Subcategory (RNA class) for MIR4648 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4648 Gene

  • MicroRNA 4648 2 3 5
  • Hsa-Mir-4648 3

External Ids for MIR4648 Gene

Previous GeneCards Identifiers for MIR4648 Gene

  • GC07U903183
  • GC07P002570

Summaries for MIR4648 Gene

Entrez Gene Summary for MIR4648 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4648 Gene

MIR4648 (MicroRNA 4648) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4648 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4648 Gene

Genomics for MIR4648 Gene

Products:

  1. Regulatory Element

GeneHancer (GH) Regulatory Elements for MIR4648 Gene

Promoters and enhancers for MIR4648 Gene
GeneHancer (GH) Identifier GH Type GH
Score		 GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites		 Gene Targets
GH07I002515 Promoter/Enhancer 2.7 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 0.8 -2.7 -2713 18.1 HDGF PKNOX1 CLOCK FOXA2 ARID4B NEUROD1 SIN3A YBX1 ZBTB7B ZNF143 LFNG BRAT1 IQCE GC07P002527 MIR4648
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR4648 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR4648 Gene

Genomic Locations for MIR4648 Gene
chr7:2,527,074-2,527,145
(GRCh38/hg38)
Size:
72 bases
Orientation:
Plus strand
chr7:2,566,708-2,566,786
(GRCh37/hg19)

Genomic View for MIR4648 Gene

Genes around MIR4648 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4648 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4648 Gene
GeneLoc Logo Genomic Neighborhood • Exon Structure • Gene Density

RefSeq DNA sequence for MIR4648 Gene

Proteins for MIR4648 Gene

Products:

  1. Antibody
  2. Protein
  3. Assay

Post-translational modifications for MIR4648 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4648 Gene

Domains & Families for MIR4648 Gene

Gene Families for MIR4648 Gene

HGNC:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4648: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4648 Gene

Function for MIR4648 Gene

Products:

  1. Animal Model
  2. CRISPR
  3. miRNA
  4. Inhibitory RNA
  5. Clone
  6. Cell Line

Phenotypes From GWAS Catalog for MIR4648 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4648 Gene

Localization for MIR4648 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4648 Gene

Pathways & Interactions for MIR4648 Gene

SuperPathways for MIR4648 Gene

PathCards logo More details on SuperPathways for MIR4648
No Data Available

Interacting Proteins for MIR4648 Gene

Gene Ontology (GO) - Biological Process for MIR4648 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4648 Gene

Drugs & Compounds for MIR4648 Gene

Products:

  1. Drug
No Compound Related Data Available

Transcripts for MIR4648 Gene

Products:

  1. CRISPR
  2. miRNA
  3. Inhibitory RNA
  4. Clone

mRNA/cDNA for MIR4648 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4648 Gene

No ASD Table

Relevant External Links for MIR4648 Gene

GeneLoc Exon Structure for
MIR4648
ECgene alternative splicing isoforms for
MIR4648

Expression for MIR4648 Gene

Products:

  1. Primer

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR4648 Gene

mRNA expression in normal human tissues for MIR4648 Gene
mRNA expression by GTEx for MIR4648 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4648 Gene:

MIR4648
genes like me logo Genes that share expression patterns with MIR4648: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4648 Gene

Orthologs for MIR4648 Gene

Evolution for MIR4648 Gene

ENSEMBL:
Gene Tree for MIR4648 (if available)
TreeFam:
Gene Tree for MIR4648 (if available)

No data available for Orthologs for MIR4648 Gene

Paralogs for MIR4648 Gene

No data available for Paralogs for MIR4648 Gene

Variants for MIR4648 Gene

Sequence variations from dbSNP and Humsavar for MIR4648 Gene

SNP ID Clin Chr 07 pos Variation AA Info Type
rs104894024 pathogenic, Spondylocostal dysostosis 3 2,525,301(+) C/A/T upstream_transcript_variant
rs148460430 uncertain-significance, Spondylocostal dysostosis 3 2,525,485(+) C/T upstream_transcript_variant
rs62444250 benign, not specified, Spondylocostal dysostosis 3 2,525,215(+) A/G/T upstream_transcript_variant
rs147266260 likely-benign, not specified 2,525,444(+) C/T upstream_transcript_variant
rs151012354 likely-benign, not specified 2,525,504(+) C/T upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR4648 Gene

Variant ID Type Subtype PubMed ID
nsv471216 CNV loss 18288195
nsv605861 CNV loss 21841781
nsv605862 CNV loss 21841781
nsv823981 CNV gain 20364138
nsv830887 CNV loss 17160897
nsv950792 CNV deletion 24416366

Additional Variant Information for MIR4648 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4648

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4648 Gene

Disorders for MIR4648 Gene

Additional Disease Information for MIR4648

ATLAS of Genetics and Cytogenetics in Oncology and Haematology

No disorders were found for MIR4648 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4648 Gene

Publications for MIR4648 Gene

  1. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H … Rovira C (Cancer research 2011) 3 58
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR4648 Gene

Sources for MIR4648 Gene

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