Aliases for MIR4648 Gene
Subcategory (RNA class) for MIR4648 Gene
miRNA
Quality Score for this RNA gene is
3
External Ids for MIR4648 Gene
- HGNC: 41560
- Entrez Gene: 100616116
- Ensembl: ENSG00000264357
- miRBase: hsa-mir-4648
Previous GeneCards Identifiers for MIR4648 Gene
- GC07U903183
- GC07P002570
Summaries for MIR4648 Gene
-
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
GeneCards Summary for MIR4648 Gene
MIR4648 (MicroRNA 4648) is an RNA Gene, and is affiliated with the miRNA class.
No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4648 Gene
Genomics for MIR4648 Gene
Regulatory Elements for MIR4648 Gene
Enhancers for MIR4648 Gene
| GeneHancer Identifier | Enhancer Score | Enhancer Sources | Gene-Enhancer Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Gene Targets for Enhancer |
|---|---|---|---|---|---|---|---|---|
| GH07G002520 | 2 | FANTOM5 Ensembl ENCODE dbSUPER | 0.7 | -0.3 | -298 | 13.2 | HDGF PKNOX1 FOXA2 SIN3A ARID4B ZBTB7B ZNF143 FOS ZNF548 ZNF263 | LFNG CHST12 BRAT1 IQCE MIR4648 |
| GH07G002515 | 1.4 | ENCODE dbSUPER | 0.4 | -9.6 | -9629 | 4.2 | HDGF CREB3L1 ARID4B SIN3A YBX1 ZNF2 ZBTB7B YY1 SLC30A9 ZNF143 | LFNG MIR4648 |
| GH07G002519 | 1.2 | ENCODE dbSUPER | 0.4 | -7.4 | -7353 | 0.2 | CREB3L1 SIN3A ZNF207 SP5 MXD4 NFYC REST KAT8 MBD2 NR2C1 | MIR4648 LFNG |
| GH07G002521 | 1.2 | ENCODE dbSUPER | 0.4 | -7.2 | -7211 | 0.0 | SIN3A MXD4 NFYC REST MBD2 KDM1A CTCF KLF1 SAP30 UBTF | MIR4648 LFNG |
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around MIR4648 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Location for MIR4648 Gene
- Chromosome:
- 7
- Start:
- 2,527,074 bp from pter
- End:
- 2,527,145 bp from pter
- Size:
- 72 bases
- Orientation:
- Plus strand
Genomic View for MIR4648 Gene
Genes around MIR4648 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 7p22.3 by Ensembl
- 7p22.3 by Entrez Gene
- 7p22.3 by HGNC
MIR4648 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for MIR4648 Gene
Proteins for MIR4648 Gene
Post-translational modifications for MIR4648 Gene
No Post-translational modifications
Antibody Products
- Search GeneTex for Antibodies for MIR4648
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for MIR4648
- Origene Custom Protein Services for MIR4648
- Search GeneTex for Proteins for MIR4648
Assay Products
No data available for DME Specific Peptides for MIR4648 Gene
Domains & Families for MIR4648 Gene
Gene Families for MIR4648 Gene
- HGNC:
Graphical View of Domain Structure for InterPro Entry
No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4648 Gene
Function for MIR4648 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for MIR4648
-
- Search ViGene Biosciences for MIR4648
CRISPR Products
- Browse CRISPR knockouts for MIR4648
miRNA Products
- Search ViGene Biosciences for MIR4648
-
Origene geneexpression products in human, mouse, rat for MIR4648
- Browse OriGene miRNA Products For MIR4648
Inhibitory RNA Products
- Search ViGene Biosciences for MIR4648
Clone Products
- GenScript: Custom all cDNA clones Services for MIR4648
- VectorBuilder custom plasmid, inducible vectors for MIR4648
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for MIR4648
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
- Search ViGene Biosciences for MIR4648
Flow Cytometry Products
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4648 Gene
Localization for MIR4648 Gene
No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4648 Gene
Transcripts for MIR4648 Gene
mRNA/cDNA for MIR4648 Gene
- (1) Ensembl transcripts including schematic representations, and UCSC links where relevant :
CRISPR Products
- Browse CRISPR knockouts for MIR4648
miRNA Products
- Search ViGene Biosciences for MIR4648
-
Origene geneexpression products in human, mouse, rat for MIR4648
- Browse OriGene miRNA Products For MIR4648
Inhibitory RNA Products
- Search ViGene Biosciences for MIR4648
Clone Products
- GenScript: Custom all cDNA clones Services for MIR4648
- VectorBuilder custom plasmid, inducible vectors for MIR4648
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for MIR4648
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
Expression for MIR4648 Gene
NURSA nuclear receptor signaling pathways regulating expression of MIR4648 Gene:
MIR4648Primer Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4648 Gene
Orthologs for MIR4648 Gene
No data available for Orthologs for MIR4648 Gene
Paralogs for MIR4648 Gene
No data available for Paralogs for MIR4648 Gene
Variants for MIR4648 Gene
| SNP ID | Clin | Chr 07 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs104894024 | Pathogenic | 2,525,301(+) | CGCTT(A/C/T)ATCGA | upstream-variant-2KB, reference, synonymous-codon, missense | |
| rs147266260 | Likely benign | 2,525,444(+) | AACTA(C/T)GTCAA | upstream-variant-2KB, reference, synonymous-codon | |
| rs151012354 | Likely benign | 2,525,504(+) | GTCTA(C/T)GTCGG | upstream-variant-2KB, reference, synonymous-codon | |
| rs139864844 | Uncertain significance | 2,525,310(+) | GAGTC(C/T)GGCAG | upstream-variant-2KB, reference, synonymous-codon | |
| rs770507072 | Uncertain significance | 2,525,723(+) | GCTGG(C/T)TTCTG | upstream-variant-2KB, reference, synonymous-codon |
Relevant External Links for MIR4648 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- MIR4648
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4648 Gene
Disorders for MIR4648 Gene
Relevant External Links for MIR4648
- Atlas of Genetics and Cytogenetics in Oncology and Haematology:
- MIR4648
No disorders were found for MIR4648 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4648 Gene
Publications for MIR4648 Gene
- Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H. … Rovira C. (Cancer Res. 2011) 3 64
- miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64
Products for MIR4648 Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Browse OriGene Antibodies
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for MIR4648
- Origene Custom Protein Services for MIR4648
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- Browse OriGene qPCR primer pairs and template standards
- Browse CRISPR knockouts for MIR4648
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Origene geneexpression products in human, mouse, rat for MIR4648
- Browse OriGene miRNA Products For MIR4648
- GenScript: Custom all cDNA clones Services for MIR4648
- GenScript Custom Purified and Recombinant Proteins Services for MIR4648
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- GenScript Custom overexpressing Cell Line Services for MIR4648
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- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
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- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
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- Browse Sino Biological cDNA Clones
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- Sino Biological Antibodies
- Sino Biological ELISA Kits and Pair Sets
- Sino Biological Cell Lysates
- Sino Biological qPCR Primers
- Sino Biological CRO Services for Proteins, Antibodies and Genes
- Sino Biological Transfection Reagents
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Cyagen custom Knockout/knockin (KOKI) mouse models for MIR4648
- VectorBuilder custom plasmid, inducible vectors for MIR4648
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for MIR4648
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for MIR4648 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
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- (128) Genetics Home Reference
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- (130) MedlinePlus
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- (133) NCBI Bookshelf
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- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer