Free for academic non-profit institutions. Other users need a Commercial license

Aliases for MIR4647 Gene

Subcategory (RNA class) for MIR4647 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4647 Gene

  • MicroRNA 4647 2 3 5
  • Hsa-Mir-4647 3
  • Mir-4647 3

External Ids for MIR4647 Gene

Previous GeneCards Identifiers for MIR4647 Gene

  • GC06U902218

Summaries for MIR4647 Gene

Entrez Gene Summary for MIR4647 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4647 Gene

MIR4647 (MicroRNA 4647) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are Glycosaminoglycan metabolism and Metabolism.

Additional gene information for MIR4647 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4647 Gene

Genomics for MIR4647 Gene

GeneHancer (GH) Regulatory Elements for MIR4647 Gene

Promoters and enhancers for MIR4647 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH06I044258 Enhancer 0.8 ENCODE 550.8 +0.6 636 0.2 ELF3 CTCF SAP130 KLF5 RAD21 CCNT2 GATAD1 NCOR1 BRD9 POLR2A MIR4647 XPO5 POLH ZNF318 POLR1C SLC29A1 AARS2 CDC5L RPS2P29 HSP90AB1
GH06I044256 Enhancer 0.7 ENCODE 550.8 -0.3 -274 0.2 HNRNPUL1 BACH1 CCNT2 POLR2B NCOR1 ZNF366 POLR2A SNRNP70 PAF1 SMAD5 MIR4647 AARS2 ZNF318 ABCC10 POLH GTPBP2 RPL34P14 SLC29A1 CDC5L SLC35B2
GH06I044253 Enhancer 0.7 ENCODE 550.8 +0.9 856 0.1 CTCF SAP130 KLF5 CCNT2 GATAD1 POLR2A ZNF143 PAF1 GATAD2A L3MBTL2 MIR4647 XPO5 POLH ZNF318 POLR1C SLC29A1 AARS2 CDC5L RPS2P29 HSP90AB1
GH06I044254 Enhancer 0.6 ENCODE 550.8 -0.4 -414 0 PAF1 HNRNPUL1 SMAD5 ZBED1 CCNT2 POLR2B CBX1 NCOR1 ZNF366 POLR2A MIR4647 AARS2 ZNF318 ABCC10 POLH GTPBP2 RPL34P14 SLC29A1 CDC5L SLC35B2
GH06I044257 Enhancer 0.6 ENCODE 550.8 -0.5 -504 0.1 PAF1 HNRNPUL1 ZBED1 CCNT2 POLR2B CBX1 NCOR1 ZNF366 POLR2A MYNN MIR4647 AARS2 ZNF318 ABCC10 POLH GTPBP2 RPL34P14 SLC29A1 CDC5L SLC35B2
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR4647 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR4647 Gene

Genomic Locations for MIR4647 Gene
chr6:44,254,206-44,254,285
(GRCh38/hg38)
Size:
80 bases
Orientation:
Minus strand
chr6:44,221,943-44,222,022
(GRCh37/hg19)

Genomic View for MIR4647 Gene

Genes around MIR4647 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4647 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4647 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4647 Gene

Proteins for MIR4647 Gene

Post-translational modifications for MIR4647 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4647 Gene

Domains & Families for MIR4647 Gene

Gene Families for MIR4647 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4647: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4647 Gene

Function for MIR4647 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4647 Gene

Localization for MIR4647 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4647 Gene

Drugs & Compounds for MIR4647 Gene

No Compound Related Data Available

Transcripts for MIR4647 Gene

mRNA/cDNA for MIR4647 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4647 Gene

No ASD Table

Relevant External Links for MIR4647 Gene

GeneLoc Exon Structure for
MIR4647
ECgene alternative splicing isoforms for
MIR4647

Expression for MIR4647 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR4647 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4647 Gene:

MIR4647
genes like me logo Genes that share expression patterns with MIR4647: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4647 Gene

Orthologs for MIR4647 Gene

Evolution for MIR4647 Gene

ENSEMBL:
Gene Tree for MIR4647 (if available)
TreeFam:
Gene Tree for MIR4647 (if available)

No data available for Orthologs for MIR4647 Gene

Paralogs for MIR4647 Gene

No data available for Paralogs for MIR4647 Gene

Variants for MIR4647 Gene

Sequence variations from dbSNP and Humsavar for MIR4647 Gene

SNP ID Clin Chr 06 pos Variation AA Info Type
rs1001629813 -- 44,254,364(-) G/C upstream_transcript_variant
rs1002161394 -- 44,254,403(-) G/C upstream_transcript_variant
rs1004870283 -- 44,256,122(-) C/G upstream_transcript_variant
rs1006892334 -- 44,254,004(-) C/T downstream_transcript_variant
rs1006944494 -- 44,253,807(-) A/G downstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR4647 Gene

Variant ID Type Subtype PubMed ID
dgv10641n54 CNV loss 21841781
nsv462936 CNV loss 19166990
nsv524398 CNV loss 19592680
nsv5282 CNV insertion 18451855
nsv603003 CNV gain 21841781

Additional Variant Information for MIR4647 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4647

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4647 Gene

Disorders for MIR4647 Gene

Additional Disease Information for MIR4647

No disorders were found for MIR4647 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4647 Gene

Publications for MIR4647 Gene

  1. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3 58
  2. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H … Rovira C (Cancer research 2011) 3 58
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR4647 Gene

Sources for MIR4647 Gene

Content
Loading form....