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Aliases for MIR4646 Gene

Subcategory (RNA class) for MIR4646 Gene


Quality Score for this RNA gene is


Aliases for MIR4646 Gene

  • MicroRNA 4646 2 3 5
  • Hsa-Mir-4646 3
  • Mir-4646 3

External Ids for MIR4646 Gene

Previous GeneCards Identifiers for MIR4646 Gene

  • GC06U902215
  • GC06M031672
  • GC06M031673
  • GC06M031702
  • GC06M031705
  • GC06M031715
  • GC06M031774
  • GC06M031826

Summaries for MIR4646 Gene

Entrez Gene Summary for MIR4646 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4646 Gene

MIR4646 (MicroRNA 4646) is an RNA Gene, and is affiliated with the miRNA class.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4646 Gene

Genomics for MIR4646 Gene

Regulatory Elements for MIR4646 Gene

Enhancers for MIR4646 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH06G031700 1.4 ENCODE dbSUPER 0.7 -1.5 -1544 3.3 MLX CREB3L1 YBX1 DMAP1 YY1 SLC30A9 ZNF263 SP3 TBX21 ZNF610 SKIV2L C4A ATF6B LSM2 LY6G5B RPL3P2 EHMT2 DDX39B PBX2 MICB
GH06G031689 1.3 ENCODE dbSUPER 0.4 +10.6 10612 1.6 HDGF PKNOX1 CREB3L1 ARNT SIN3A ARID4B FOS KLF13 PAF1 JUNB LY6G5C SKIV2L LY6G5B AGER LOC105375018 MIR4646
GH06G031694 0.7 dbSUPER 0.4 +5.9 5904 0.9 HDGF ZNF362 CEBPB RBBP5 CDC5L ZBTB7A GLIS2 IKZF1 HMBOX1 FOXJ2 LY6G5C LOC105375018 MIR4646
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR4646 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR4646 Gene

31,701,029 bp from pter
31,701,091 bp from pter
63 bases
Minus strand

Genomic View for MIR4646 Gene

Genes around MIR4646 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4646 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4646 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

Proteins for MIR4646 Gene

Post-translational modifications for MIR4646 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4646 Gene

Domains & Families for MIR4646 Gene

Gene Families for MIR4646 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4646: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4646 Gene

Function for MIR4646 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4646 Gene

Localization for MIR4646 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4646 Gene

Pathways & Interactions for MIR4646 Gene

SuperPathways for MIR4646 Gene

No Data Available

Interacting Proteins for MIR4646 Gene

Gene Ontology (GO) - Biological Process for MIR4646 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR4646 Gene

Drugs & Compounds for MIR4646 Gene

No Compound Related Data Available

Transcripts for MIR4646 Gene

mRNA/cDNA for MIR4646 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4646 Gene

No ASD Table

Relevant External Links for MIR4646 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR4646 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4646 Gene:

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4646 Gene

Orthologs for MIR4646 Gene

Evolution for MIR4646 Gene

Gene Tree for MIR4646 (if available)
Gene Tree for MIR4646 (if available)

No data available for Orthologs for MIR4646 Gene

Paralogs for MIR4646 Gene

No data available for Paralogs for MIR4646 Gene

Variants for MIR4646 Gene

Sequence variations from dbSNP and Humsavar for MIR4646 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type
rs1001055964 -- 31,701,842(+) ACATG(A/T)TTTCC intron-variant, upstream-variant-2KB
rs1001266566 -- 31,700,673(+) GGGAG(A/G)ATCAC intron-variant, downstream-variant-500B
rs1004993098 -- 31,701,455(+) TATCA(C/T)ATTTG intron-variant, upstream-variant-2KB
rs1007297150 -- 31,702,371(+) ATTGG(A/G)CGATT intron-variant, upstream-variant-2KB
rs1008115128 -- 31,702,687(+) GGACC(A/G)ACGGA intron-variant, nc-transcript-variant, upstream-variant-2KB, reference, missense

Structural Variations from Database of Genomic Variants (DGV) for MIR4646 Gene

Variant ID Type Subtype PubMed ID
dgv10403n54 CNV loss 21841781
dgv10404n54 CNV loss 21841781
nsv1073969 CNV deletion 25765185
nsv1112900 CNV deletion 24896259
nsv1126749 CNV deletion 24896259
nsv1161370 CNV deletion 26073780

Relevant External Links for MIR4646 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4646 Gene

Disorders for MIR4646 Gene

Relevant External Links for MIR4646

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR4646 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4646 Gene

Publications for MIR4646 Gene

  1. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A. … Griffiths-Jones S. (Nucleic Acids Res. 2011) 3 64
  2. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H. … Rovira C. (Cancer Res. 2011) 3 64
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4646 Gene

Sources for MIR4646 Gene

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