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Aliases for MIR4645 Gene

Subcategory (RNA class) for MIR4645 Gene


Quality Score for this RNA gene is


Aliases for MIR4645 Gene

  • MicroRNA 4645 2 3
  • Hsa-Mir-4645 3

External Ids for MIR4645 Gene

Previous GeneCards Identifiers for MIR4645 Gene

  • GC06U902230
  • GC06M002865
  • GC06M002866
  • GC06M002868

Summaries for MIR4645 Gene

Entrez Gene Summary for MIR4645 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4645 Gene

MIR4645 (MicroRNA 4645) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4645 Gene

Genomics for MIR4645 Gene

Genomic Location for MIR4645 Gene

2,854,031 bp from pter
2,854,107 bp from pter
77 bases
Minus strand

Genomic View for MIR4645 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR4645 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4645 Gene

ORGUL Member Location for MIR4645 Gene

ORGUL Member Location for MIR4645 gene

No data available for Regulatory Elements for MIR4645 Gene

Proteins for MIR4645 Gene

Post-translational modifications for MIR4645 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4645 Gene

Domains for MIR4645 Gene

Gene Families for MIR4645 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4645: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4645 Gene

Function for MIR4645 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4645 Gene

Localization for MIR4645 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4645 Gene

Pathways for MIR4645 Gene

SuperPathways for MIR4645 Gene

No Data Available

Interacting Proteins for MIR4645 Gene

Gene Ontology (GO) - Biological Process for MIR4645 Gene


No data available for Pathways by source for MIR4645 Gene

Transcripts for MIR4645 Gene

mRNA/cDNA for MIR4645 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4645 Gene

No ASD Table

Relevant External Links for MIR4645 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR4645 Gene

mRNA expression in normal human tissues for MIR4645 Gene

genes like me logo Genes that share expressions with MIR4645: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for MIR4645 Gene

Orthologs for MIR4645 Gene

Evolution for MIR4645 Gene

Gene Tree for MIR4645 (if available)
Gene Tree for MIR4645 (if available)

No data available for Orthologs for MIR4645 Gene

Paralogs for MIR4645 Gene

No data available for Paralogs for MIR4645 Gene

Variants for MIR4645 Gene

Sequence variations from dbSNP and Humsavar for MIR4645 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type MAF
rs577619572 -- 2,853,745(+) TTATA(C/T)TTTTC downstream-variant-500B
rs576753783 -- 2,853,787(+) GGGAA(A/G)GGCCA downstream-variant-500B
rs568475655 -- 2,854,099(+) TGGTT(C/T)CCCTA nc-transcript-variant
rs563992072 -- 2,854,031(+) CTCCA(A/T)GATAG nc-transcript-variant
rs563072066 -- 2,853,762(+) TTAGA(C/G)TGGGG downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for MIR4645 Gene

Variant ID Type Subtype PubMed ID
nsv830575 CNV Loss 17160897

Relevant External Links for MIR4645 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MIR4645 Gene

Disorders for MIR4645 Gene

No disorders were found for MIR4645 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for MIR4645 Gene

Publications for MIR4645 Gene

  1. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  2. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H. … Rovira C. (Cancer Res. 2011) 3

Products for MIR4645 Gene

Sources for MIR4645 Gene

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