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Aliases for MIR4644 Gene

Subcategory (RNA class) for MIR4644 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4644 Gene

  • MicroRNA 4644 2 3 5
  • Hsa-Mir-4644 3

External Ids for MIR4644 Gene

Previous GeneCards Identifiers for MIR4644 Gene

  • GC06U902211
  • GC06P170641

Summaries for MIR4644 Gene

Entrez Gene Summary for MIR4644 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4644 Gene

MIR4644 (MicroRNA 4644) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4644 Gene

Genomics for MIR4644 Gene

Regulatory Elements for MIR4644 Gene

Enhancers for MIR4644 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH06F170316 0.2 ENCODE 0.4 -13.5 -13456 1.1 FAM120B DLL1 MIR4644
GH06F170305 1.1 ENCODE 0.3 -23.6 -23632 3.4 HDGF PKNOX1 CREB3L1 MLX ARID4B SIN3A DMAP1 ZNF2 SLC30A9 ZNF143 TBP RPL12P23 OR4F7P LOC101929692 FAM120B ENSG00000266896 LOC102724511 PSMB1 DLL1 MIR4644
GH06F170310 0.2 Ensembl 0.3 -20.4 -20361 0.4 FAM120B DLL1 MIR4644
GH06F170313 0.2 ENCODE 0.3 -16.7 -16672 0.5 ZNF263 FAM120B ENSG00000261003 DLL1 MIR4644
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around MIR4644 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR4644 Gene

Chromosome:
6
Start:
170,330,761 bp from pter
End:
170,330,844 bp from pter
Size:
84 bases
Orientation:
Plus strand

Genomic View for MIR4644 Gene

Genes around MIR4644 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4644 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4644 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4644 Gene

Proteins for MIR4644 Gene

Post-translational modifications for MIR4644 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4644 Gene

Domains & Families for MIR4644 Gene

Gene Families for MIR4644 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4644: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4644 Gene

Function for MIR4644 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4644 Gene

Localization for MIR4644 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4644 Gene

Pathways & Interactions for MIR4644 Gene

SuperPathways for MIR4644 Gene

No Data Available

Interacting Proteins for MIR4644 Gene

Gene Ontology (GO) - Biological Process for MIR4644 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4644 Gene

Transcripts for MIR4644 Gene

mRNA/cDNA for MIR4644 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4644 Gene

No ASD Table

Relevant External Links for MIR4644 Gene

GeneLoc Exon Structure for
MIR4644
ECgene alternative splicing isoforms for
MIR4644

Expression for MIR4644 Gene

mRNA expression in normal human tissues for MIR4644 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4644 Gene:

MIR4644
genes like me logo Genes that share expression patterns with MIR4644: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR4644 Gene

Orthologs for MIR4644 Gene

Evolution for MIR4644 Gene

ENSEMBL:
Gene Tree for MIR4644 (if available)
TreeFam:
Gene Tree for MIR4644 (if available)

No data available for Orthologs for MIR4644 Gene

Paralogs for MIR4644 Gene

No data available for Paralogs for MIR4644 Gene

Variants for MIR4644 Gene

Sequence variations from dbSNP and Humsavar for MIR4644 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type
rs112530284 -- 170,330,466(+) CCTGC(C/G)TAGCT nc-transcript-variant, upstream-variant-2KB, reference, missense, utr-variant-5-prime
rs113034054 -- 170,329,595(+) CCGAC(-/T)TTTTT intron-variant, upstream-variant-2KB
rs115194758 -- 170,329,711(+) TGGAC(C/T)GATAC intron-variant, upstream-variant-2KB
rs116383148 -- 170,329,234(+) ATCTC(C/T)AGTCT intron-variant, upstream-variant-2KB
rs117630758 -- 170,330,049(+) GTCTT(A/C)TTTAC intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR4644 Gene

Variant ID Type Subtype PubMed ID
esv2759497 CNV gain+loss 17122850
nsv428158 CNV gain 18775914

Relevant External Links for MIR4644 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4644

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4644 Gene

Disorders for MIR4644 Gene

Relevant External Links for MIR4644

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR4644

No disorders were found for MIR4644 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4644 Gene

Publications for MIR4644 Gene

  1. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H. … Rovira C. (Cancer Res. 2011) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4644 Gene

Sources for MIR4644 Gene

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