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Aliases for MIR4643 Gene

Subcategory (RNA class) for MIR4643 Gene


Quality Score for this RNA gene is


Aliases for MIR4643 Gene

  • MicroRNA 4643 2 3
  • Hsa-Mir-4643 3

External Ids for MIR4643 Gene

Previous GeneCards Identifiers for MIR4643 Gene

  • GC06U902220
  • GC06P092233

Summaries for MIR4643 Gene

Entrez Gene Summary for MIR4643 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4643 Gene

MIR4643 (MicroRNA 4643) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4643 Gene

Genomics for MIR4643 Gene

Genomic Location for MIR4643 Gene

91,521,660 bp from pter
91,521,737 bp from pter
78 bases
Plus strand

Genomic View for MIR4643 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR4643 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4643 Gene

No data available for Regulatory Elements for MIR4643 Gene

Proteins for MIR4643 Gene

Post-translational modifications for MIR4643 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4643 Gene

Domains for MIR4643 Gene

Gene Families for MIR4643 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4643: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4643 Gene

Function for MIR4643 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4643 Gene

Localization for MIR4643 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4643 Gene

Pathways for MIR4643 Gene

SuperPathways for MIR4643 Gene

No Data Available

Interacting Proteins for MIR4643 Gene

Gene Ontology (GO) - Biological Process for MIR4643 Gene


No data available for Pathways by source for MIR4643 Gene

Transcripts for MIR4643 Gene

mRNA/cDNA for MIR4643 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4643 Gene

No ASD Table

Relevant External Links for MIR4643 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR4643 Gene

No Expression Related Data Available

Primer Products

In Situ Assay Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for MIR4643 Gene

Orthologs for MIR4643 Gene

Evolution for MIR4643 Gene

Gene Tree for MIR4643 (if available)
Gene Tree for MIR4643 (if available)

No data available for Orthologs for MIR4643 Gene

Paralogs for MIR4643 Gene

No data available for Paralogs for MIR4643 Gene

Variants for MIR4643 Gene

Sequence variations from dbSNP and Humsavar for MIR4643 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type MAF
rs539897228 -- 91,520,135(+) AGTGG(C/T)GCAAT upstream-variant-2KB
rs538888403 -- 91,520,721(+) TTAAA(A/G)CTCTT upstream-variant-2KB
rs538841280 -- 91,521,167(+) ATTCA(A/G)TGGTT upstream-variant-2KB
rs537254062 -- 91,521,938(+) ACAGG(-/T)TTTTT downstream-variant-500B
rs536298822 -- 91,521,417(+) AAAAA(A/G)TTAAA upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR4643 Gene

Variant ID Type Subtype PubMed ID
nsv886342 CNV Loss 21882294

Relevant External Links for MIR4643 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MIR4643 Gene

Disorders for MIR4643 Gene

No disorders were found for MIR4643 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for MIR4643 Gene

Publications for MIR4643 Gene

  1. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  2. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H. … Rovira C. (Cancer Res. 2011) 3

Products for MIR4643 Gene

Sources for MIR4643 Gene

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