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Aliases for MIR4642 Gene

Subcategory (RNA class) for MIR4642 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4642 Gene

  • MicroRNA 4642 2 3 5
  • Hsa-Mir-4642 3

External Ids for MIR4642 Gene

Previous GeneCards Identifiers for MIR4642 Gene

  • GC06U902216
  • GC06P044405

Summaries for MIR4642 Gene

Entrez Gene Summary for MIR4642 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4642 Gene

MIR4642 (MicroRNA 4642) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4642 Gene

Genomics for MIR4642 Gene

Regulatory Elements for MIR4642 Gene

Enhancers for MIR4642 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH06F044439 0.5 ENCODE 0.8 +4.3 4258 0.2 JUND ATF3 FOS MIR4642 GC06P044450
GH06F044446 0.9 ENCODE 0.4 +11.5 11505 1.2 PKNOX1 INSM2 ZNF76 FEZF1 ZEB1 YY1 ZNF121 ZNF366 FOS ZNF362 POLH RPS2P29 LOC101929726 CAPN11 GC06P044450 MIR4642
GH06F044428 0.4 ENCODE 0.4 -6.8 -6783 0.2 ZNF362 GC06P044423 GC06P044424 MIR4642
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR4642 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR4642 Gene

Chromosome:
6
Start:
44,435,641 bp from pter
End:
44,435,722 bp from pter
Size:
82 bases
Orientation:
Plus strand

Genomic View for MIR4642 Gene

Genes around MIR4642 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4642 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4642 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4642 Gene

Proteins for MIR4642 Gene

Post-translational modifications for MIR4642 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4642 Gene

Domains & Families for MIR4642 Gene

Gene Families for MIR4642 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4642: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4642 Gene

Function for MIR4642 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4642 Gene

Localization for MIR4642 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4642 Gene

Pathways & Interactions for MIR4642 Gene

SuperPathways for MIR4642 Gene

No Data Available

Interacting Proteins for MIR4642 Gene

Gene Ontology (GO) - Biological Process for MIR4642 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4642 Gene

Transcripts for MIR4642 Gene

mRNA/cDNA for MIR4642 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4642 Gene

No ASD Table

Relevant External Links for MIR4642 Gene

GeneLoc Exon Structure for
MIR4642
ECgene alternative splicing isoforms for
MIR4642

Expression for MIR4642 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR4642 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4642 Gene:

MIR4642
genes like me logo Genes that share expression patterns with MIR4642: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR4642 Gene

Orthologs for MIR4642 Gene

Evolution for MIR4642 Gene

ENSEMBL:
Gene Tree for MIR4642 (if available)
TreeFam:
Gene Tree for MIR4642 (if available)

No data available for Orthologs for MIR4642 Gene

Paralogs for MIR4642 Gene

No data available for Paralogs for MIR4642 Gene

Variants for MIR4642 Gene

Sequence variations from dbSNP and Humsavar for MIR4642 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type
rs111690210 -- 44,436,134(+) AAATG(A/T)GATAC intron-variant, downstream-variant-500B
rs111880021 -- 44,435,662(+) CGTCC(A/C)CTGGT intron-variant, nc-transcript-variant
rs113305710 -- 44,436,039(+) TCCCA(A/G)AGTGC intron-variant, downstream-variant-500B
rs113781910 -- 44,434,541(+) GCTGA(C/T)TGATG intron-variant, upstream-variant-2KB
rs114459995 -- 44,436,067(+) GCCAC(C/T)GTGCC intron-variant, downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for MIR4642 Gene

Variant ID Type Subtype PubMed ID
nsv517370 CNV gain+loss 19592680
nsv1019145 CNV gain 25217958

Relevant External Links for MIR4642 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4642

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4642 Gene

Disorders for MIR4642 Gene

Relevant External Links for MIR4642

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR4642

No disorders were found for MIR4642 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4642 Gene

Publications for MIR4642 Gene

  1. A genome-wide association study identifies susceptibility loci for ossification of the posterior longitudinal ligament of the spine. (PMID: 25064007) Nakajima M. … Ikegawa S. (Nat. Genet. 2014) 3 64
  2. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H. … Rovira C. (Cancer Res. 2011) 3 64
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4642 Gene

Sources for MIR4642 Gene

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