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Aliases for MIR4639 Gene

Subcategory (RNA class) for MIR4639 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4639 Gene

  • MicroRNA 4639 2 3 5
  • Hsa-Mir-4639 3

External Ids for MIR4639 Gene

Previous GeneCards Identifiers for MIR4639 Gene

  • GC06U902227

Summaries for MIR4639 Gene

Entrez Gene Summary for MIR4639 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4639 Gene

MIR4639 (MicroRNA 4639) is an RNA Gene, and is affiliated with the miRNA class.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4639 Gene

Genomics for MIR4639 Gene

Regulatory Elements for MIR4639 Gene

Enhancers for MIR4639 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH06G016136 1.3 Ensembl ENCODE dbSUPER 0.7 -4.6 -4628 1.8 ZNF146 ZNF837 INSM2 SIN3A FEZF1 ZNF101 ZEB1 FOSL1 GATA2 ZNF366 MIR4639 MYLIP
GH06G016144 1 dbSUPER 0.7 +3.8 3780 2.5 PKNOX1 ARNT SIN3A FEZF1 ZNF2 ZNF121 GLIS2 GATA2 ZNF488 TSHZ1 GC06M016150 MIR4639
GH06G016128 1.4 ENCODE dbSUPER 0.4 -11.2 -11187 4.0 CREB3L1 MLX AGO1 ZFP64 DMAP1 FEZF1 SLC30A9 ZNF143 ZNF416 SP3 RNU6-1114P MYLIP MIR4639
GH06G016135 0.9 Ensembl dbSUPER 0.4 -6.2 -6247 0.6 HDGF POLR2A ADNP HMBOX1 NFE2 ZNF600 SUPT5H RBFOX2 MIR4639 MYLIP
GH06G016133 0.8 Ensembl dbSUPER 0.4 -8.5 -8456 0.2 OSR2 PKNOX1 PBX2 REST ZNF600 RNU6-1114P MYLIP MIR4639
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR4639 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR4639 Gene

Chromosome:
6
Start:
16,141,556 bp from pter
End:
16,141,624 bp from pter
Size:
69 bases
Orientation:
Plus strand

Genomic View for MIR4639 Gene

Genes around MIR4639 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4639 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4639 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4639 Gene

Proteins for MIR4639 Gene

Post-translational modifications for MIR4639 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4639 Gene

Domains & Families for MIR4639 Gene

Gene Families for MIR4639 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4639: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4639 Gene

Function for MIR4639 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4639 Gene

Localization for MIR4639 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4639 Gene

Pathways & Interactions for MIR4639 Gene

SuperPathways for MIR4639 Gene

No Data Available

Interacting Proteins for MIR4639 Gene

Gene Ontology (GO) - Biological Process for MIR4639 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4639 Gene

Drugs & Compounds for MIR4639 Gene

No Compound Related Data Available

Transcripts for MIR4639 Gene

mRNA/cDNA for MIR4639 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4639 Gene

No ASD Table

Relevant External Links for MIR4639 Gene

GeneLoc Exon Structure for
MIR4639
ECgene alternative splicing isoforms for
MIR4639

Expression for MIR4639 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR4639 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4639 Gene:

MIR4639
genes like me logo Genes that share expression patterns with MIR4639: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4639 Gene

Orthologs for MIR4639 Gene

Evolution for MIR4639 Gene

ENSEMBL:
Gene Tree for MIR4639 (if available)
TreeFam:
Gene Tree for MIR4639 (if available)

No data available for Orthologs for MIR4639 Gene

Paralogs for MIR4639 Gene

No data available for Paralogs for MIR4639 Gene

Variants for MIR4639 Gene

Sequence variations from dbSNP and Humsavar for MIR4639 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type
rs1000773486 -- 16,139,998(+) AGACT(C/G)TCAGT intron-variant, upstream-variant-2KB
rs1001122504 -- 16,139,604(+) AGAAG(C/T)CTTTT intron-variant, upstream-variant-2KB
rs1003625312 -- 16,141,652(+) AAGGA(A/G)GCCCT downstream-variant-500B, reference, synonymous-codon, utr-variant-5-prime
rs1003681492 -- 16,142,075(+) AGGGA(G/T)CAGCA intron-variant, downstream-variant-500B
rs1004035555 -- 16,141,758(+) CCAAG(A/T)ATAAC downstream-variant-500B, reference, missense, utr-variant-5-prime

Structural Variations from Database of Genomic Variants (DGV) for MIR4639 Gene

Variant ID Type Subtype PubMed ID
nsv5209 CNV insertion 18451855
nsv950132 CNV duplication 24416366

Relevant External Links for MIR4639 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4639

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4639 Gene

Disorders for MIR4639 Gene

Relevant External Links for MIR4639

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR4639

No disorders were found for MIR4639 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4639 Gene

Publications for MIR4639 Gene

  1. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H. … Rovira C. (Cancer Res. 2011) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4639 Gene

Sources for MIR4639 Gene

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