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Aliases for MIR4637 Gene

Subcategory (RNA class) for MIR4637 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR4637 Gene

  • MicroRNA 4637 2 3 5
  • Hsa-Mir-4637 3

External Ids for MIR4637 Gene

Previous GeneCards Identifiers for MIR4637 Gene

  • GC05U901566

Summaries for MIR4637 Gene

Entrez Gene Summary for MIR4637 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4637 Gene

MIR4637 (MicroRNA 4637) is an RNA Gene, and is affiliated with the miRNA class.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4637 Gene

Genomics for MIR4637 Gene

Regulatory Elements for MIR4637 Gene

Enhancers for MIR4637 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH05G014809 1.8 FANTOM5 Ensembl ENCODE dbSUPER 0.4 +15.6 15606 2.3 PKNOX1 ATF1 WRNIP1 GATA2 ZNF143 FOS JUNB TBX21 NFIL3 SMARCA4 ANKH OTULIN FAM105A RBBP4P1 MIR4637
GH05G014829 0.7 dbSUPER 0.7 -4.6 -4643 3.2 ZSCAN4 MAX REST ZIC2 RAD21 FOXA1 YY1 JUND ZFHX2 GLIS1 ANKH MIR4637
GH05G014816 1 ENCODE dbSUPER 0.4 +9.0 9012 1.7 BHLHE40 MAX CEBPB CEBPG EBF1 TBX21 EP300 RAD21 YY1 JUND MIR4637 RBBP4P1
GH05G014805 0.8 ENCODE dbSUPER 0.4 +19.3 19281 2.2 FOSL1 GLIS1 BHLHE40 FOXP2 ZBTB40 NR2F2 NR2C2 RBBP4P1 MIR4637
GH05G014868 1 ENCODE 0.3 -44.8 -44772 5.5 PKNOX1 AGO1 SIN3A ZNF2 YY1 GLIS2 ZNF143 DEK TSHZ1 REST ANKH MIR4637
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR4637 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR4637 Gene

Chromosome:
5
Start:
14,825,929 bp from pter
End:
14,826,012 bp from pter
Size:
84 bases
Orientation:
Minus strand

Genomic View for MIR4637 Gene

Genes around MIR4637 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4637 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4637 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4637 Gene

ORGUL Member Location for MIR4637 Gene

ORGUL Member Location for MIR4637 gene

Proteins for MIR4637 Gene

Post-translational modifications for MIR4637 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4637 Gene

Domains & Families for MIR4637 Gene

Gene Families for MIR4637 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4637: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4637 Gene

Function for MIR4637 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4637 Gene

Localization for MIR4637 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4637 Gene

Pathways & Interactions for MIR4637 Gene

SuperPathways for MIR4637 Gene

No Data Available

Interacting Proteins for MIR4637 Gene

Gene Ontology (GO) - Biological Process for MIR4637 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4637 Gene

Drugs & Compounds for MIR4637 Gene

No Compound Related Data Available

Transcripts for MIR4637 Gene

mRNA/cDNA for MIR4637 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4637 Gene

No ASD Table

Relevant External Links for MIR4637 Gene

GeneLoc Exon Structure for
MIR4637
ECgene alternative splicing isoforms for
MIR4637

Expression for MIR4637 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR4637 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4637 Gene:

MIR4637
genes like me logo Genes that share expression patterns with MIR4637: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4637 Gene

Orthologs for MIR4637 Gene

Evolution for MIR4637 Gene

ENSEMBL:
Gene Tree for MIR4637 (if available)
TreeFam:
Gene Tree for MIR4637 (if available)

No data available for Orthologs for MIR4637 Gene

Paralogs for MIR4637 Gene

No data available for Paralogs for MIR4637 Gene

Variants for MIR4637 Gene

Sequence variations from dbSNP and Humsavar for MIR4637 Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type
rs1000001167 -- 14,827,426(+) CAGCT(A/G)CTAGT intron-variant, upstream-variant-2KB
rs1001631839 -- 14,826,506(+) ATGGG(G/T)ATAAT intron-variant, upstream-variant-2KB
rs1003519747 -- 14,827,844(+) TTTTA(C/T)TTCAG intron-variant, upstream-variant-2KB
rs1004063503 -- 14,827,500(+) TGTTA(C/T)GCAGG intron-variant, upstream-variant-2KB
rs10043575 -- 14,826,577(+) ATAAG(A/C)TCAAA intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR4637 Gene

Variant ID Type Subtype PubMed ID
nsv1018187 CNV gain 25217958
nsv1148187 OTHER inversion 26484159
nsv830212 CNV loss 17160897

Relevant External Links for MIR4637 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4637

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4637 Gene

Disorders for MIR4637 Gene

Relevant External Links for MIR4637

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR4637

No disorders were found for MIR4637 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4637 Gene

Publications for MIR4637 Gene

  1. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H. … Rovira C. (Cancer Res. 2011) 3 64
  2. Discovery of new microRNAs by small RNAome deep sequencing in childhood acute lymphoblastic leukemia. (PMID: 21606961) Schotte D. … den Boer M.L. (Leukemia 2011) 3 64
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4637 Gene

Sources for MIR4637 Gene

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