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Aliases for MIR4635 Gene

Subcategory (RNA class) for MIR4635 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4635 Gene

  • MicroRNA 4635 2 3 5
  • Hsa-Mir-4635 3

External Ids for MIR4635 Gene

Previous GeneCards Identifiers for MIR4635 Gene

  • GC05U901572

Summaries for MIR4635 Gene

Entrez Gene Summary for MIR4635 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4635 Gene

MIR4635 (MicroRNA 4635) is an RNA Gene, and is affiliated with the miRNA class.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4635 Gene

Genomics for MIR4635 Gene

Regulatory Elements for MIR4635 Gene

Enhancers for MIR4635 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH05G001067 1.2 FANTOM5 ENCODE 0.7 -4.9 -4887 0.4 ATF1 CREB3L1 ARNT E2F7 TCF12 ZNF766 ELK1 GATA2 NCOA1 MEF2D NKD2 ZDHHC11 MIR4635 GC05M001107
GH05G001101 1.8 FANTOM5 ENCODE dbSUPER 0.3 -43.9 -43902 11.5 HDGF CREB3L1 MLX ZFP64 ARID4B SIN3A DMAP1 YY1 SLC30A9 ZNF766 SLC12A7 CTD-3080P12.3 TPPP LPCAT1 GC05M001107 MIR4635
GH05G001096 1.2 Ensembl ENCODE dbSUPER 0.3 -35.0 -34998 2.1 ZBTB10 ETV1 MAX ZBTB7A RAD21 YY1 FOXA1 GABPA ZNF366 HNF4G SLC12A7 LOC100506688 GC05M001107 MIR4635
GH05G001080 0.8 FANTOM5 dbSUPER 0.4 -17.7 -17715 0.2 POLR2A SMARCA4 RBFOX2 MIR4635 GC05M001107
GH05G001089 0.9 ENCODE dbSUPER 0.3 -28.6 -28574 4.8 KLF1 MAX MNT RAD21 YY1 GABPA NR2F2 GLIS2 HNF4A ZNF600 SLC12A7 SLC9A3-AS1 GC05M001107 MIR4635
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR4635 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR4635 Gene

Chromosome:
5
Start:
1,062,896 bp from pter
End:
1,062,974 bp from pter
Size:
79 bases
Orientation:
Minus strand

Genomic View for MIR4635 Gene

Genes around MIR4635 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4635 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4635 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4635 Gene

Proteins for MIR4635 Gene

Post-translational modifications for MIR4635 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4635 Gene

Domains & Families for MIR4635 Gene

Gene Families for MIR4635 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4635: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4635 Gene

Function for MIR4635 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4635 Gene

Localization for MIR4635 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4635 Gene

Pathways & Interactions for MIR4635 Gene

SuperPathways for MIR4635 Gene

No Data Available

Interacting Proteins for MIR4635 Gene

Gene Ontology (GO) - Biological Process for MIR4635 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4635 Gene

Drugs & Compounds for MIR4635 Gene

No Compound Related Data Available

Transcripts for MIR4635 Gene

mRNA/cDNA for MIR4635 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4635 Gene

No ASD Table

Relevant External Links for MIR4635 Gene

GeneLoc Exon Structure for
MIR4635
ECgene alternative splicing isoforms for
MIR4635

Expression for MIR4635 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR4635 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4635 Gene:

MIR4635
genes like me logo Genes that share expression patterns with MIR4635: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4635 Gene

Orthologs for MIR4635 Gene

Evolution for MIR4635 Gene

ENSEMBL:
Gene Tree for MIR4635 (if available)
TreeFam:
Gene Tree for MIR4635 (if available)

No data available for Orthologs for MIR4635 Gene

Paralogs for MIR4635 Gene

No data available for Paralogs for MIR4635 Gene

Variants for MIR4635 Gene

Sequence variations from dbSNP and Humsavar for MIR4635 Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type
rs1001045684 -- 1,062,495(+) CCCTC(A/G)GCCTA intron-variant, nc-transcript-variant, downstream-variant-500B
rs1001325383 -- 1,062,796(+) GACAG(-/TC)TCTAT intron-variant, downstream-variant-500B
rs1001351232 -- 1,063,038(+) AGCAG(G/T)CATGG intron-variant, upstream-variant-2KB
rs1001879757 -- 1,063,834(+) GCCCT(C/T)GGGAC intron-variant, upstream-variant-2KB
rs1002941902 -- 1,064,459(+) AATCC(C/T)CCAGC intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR4635 Gene

Variant ID Type Subtype PubMed ID
dgv686n27 CNV loss 19166990
dgv9521n54 CNV loss 21841781
dgv9522n54 CNV loss 21841781
esv2759316 CNV gain+loss 17122850
esv27870 CNV gain+loss 19812545
esv3575810 CNV gain 25503493
esv3603795 CNV gain 21293372
esv3894109 CNV gain 25118596
nsv10654 CNV gain+loss 18304495
nsv1133013 OTHER inversion 24896259
nsv1147234 OTHER inversion 26484159
nsv428459 CNV gain+loss 18775914
nsv461896 CNV loss 19166990
nsv461900 CNV loss 19166990
nsv469577 CNV loss 16826518
nsv470984 CNV loss 18288195
nsv527182 CNV loss 19592680
nsv596629 CNV gain 21841781
nsv596788 CNV loss 21841781
nsv822953 CNV gain 20364138
nsv950627 CNV deletion 24416366

Relevant External Links for MIR4635 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4635

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4635 Gene

Disorders for MIR4635 Gene

Relevant External Links for MIR4635

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR4635

No disorders were found for MIR4635 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4635 Gene

Publications for MIR4635 Gene

  1. Genome-wide association study identifies multiple susceptibility loci for pancreatic cancer. (PMID: 25086665) Wolpin B.M. … Amundadottir L.T. (Nat. Genet. 2014) 3 64
  2. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H. … Rovira C. (Cancer Res. 2011) 3 64
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4635 Gene

Sources for MIR4635 Gene

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