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Aliases for MIR4633 Gene

Subcategory (RNA class) for MIR4633 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4633 Gene

  • MicroRNA 4633 2 3 5
  • Hsa-Mir-4633 3

External Ids for MIR4633 Gene

Previous GeneCards Identifiers for MIR4633 Gene

  • GC05U901571
  • GC05P128435

Summaries for MIR4633 Gene

Entrez Gene Summary for MIR4633 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4633 Gene

MIR4633 (MicroRNA 4633) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4633 Gene

Genomics for MIR4633 Gene

Regulatory Elements for MIR4633 Gene

Enhancers for MIR4633 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH05F129093 1.1 ENCODE 0.8 -2.8 -2775 2.4 PKNOX1 MLX ZFP64 ARID4B SIN3A DMAP1 ZNF2 YY1 ZNF416 KLF13 SLC27A6 ISOC1 MIR4633
GH05F129097 0.7 Ensembl 0.8 +1.0 1013 1.8 TAL1 FEZF1 EBF1 ZNF664 GATA3 ZNF316 NR2F6 HES1 NR2F1 CEBPB ISOC1 SLC27A6 MIR4633 LOC102723654
GH05F129096 0.6 FANTOM5 0.8 -0.8 -817 0.3 GATA2 HLF SCRT2 MYNN ZEB2 ISOC1 SLC27A6 MIR4633
GH05F129125 1.1 Ensembl ENCODE 0.3 +28.5 28529 1.3 CTCF PKNOX1 CEBPG RAD21 YY1 GATA3 CTBP1 GATA2 ZNF169 HNF4G ISOC1 LOC102723654 MIR4633
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR4633 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR4633 Gene

Chromosome:
5
Start:
129,097,688 bp from pter
End:
129,097,766 bp from pter
Size:
79 bases
Orientation:
Plus strand

Genomic View for MIR4633 Gene

Genes around MIR4633 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4633 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4633 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4633 Gene

Proteins for MIR4633 Gene

Post-translational modifications for MIR4633 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4633 Gene

Domains & Families for MIR4633 Gene

Gene Families for MIR4633 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4633: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4633 Gene

Function for MIR4633 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4633 Gene

Localization for MIR4633 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4633 Gene

Pathways & Interactions for MIR4633 Gene

SuperPathways for MIR4633 Gene

No Data Available

Interacting Proteins for MIR4633 Gene

Gene Ontology (GO) - Biological Process for MIR4633 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4633 Gene

Transcripts for MIR4633 Gene

mRNA/cDNA for MIR4633 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4633 Gene

No ASD Table

Relevant External Links for MIR4633 Gene

GeneLoc Exon Structure for
MIR4633
ECgene alternative splicing isoforms for
MIR4633

Expression for MIR4633 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR4633 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4633 Gene:

MIR4633
genes like me logo Genes that share expression patterns with MIR4633: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR4633 Gene

Orthologs for MIR4633 Gene

Evolution for MIR4633 Gene

ENSEMBL:
Gene Tree for MIR4633 (if available)
TreeFam:
Gene Tree for MIR4633 (if available)

No data available for Orthologs for MIR4633 Gene

Paralogs for MIR4633 Gene

No data available for Paralogs for MIR4633 Gene

Variants for MIR4633 Gene

Sequence variations from dbSNP and Humsavar for MIR4633 Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type
rs111475692 -- 129,096,612(+) CTTCA(A/G)GCGTT intron-variant, upstream-variant-2KB
rs112440035 -- 129,096,859(+) GCTCT(C/G)TAAGA intron-variant, upstream-variant-2KB
rs114356696 -- 129,095,836(+) GTGCT(C/G)TCATG intron-variant, upstream-variant-2KB
rs114901680 -- 129,095,849(+) AGGCG(A/G)GTTAA intron-variant, upstream-variant-2KB
rs115961518 -- 129,098,141(+) TATTC(A/T)GACAG intron-variant, downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for MIR4633 Gene

Variant ID Type Subtype PubMed ID
nsv1015525 CNV loss 25217958
nsv599701 CNV gain 21841781
nsv830485 CNV gain 17160897

Relevant External Links for MIR4633 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4633

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4633 Gene

Disorders for MIR4633 Gene

Relevant External Links for MIR4633

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR4633

No disorders were found for MIR4633 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4633 Gene

Publications for MIR4633 Gene

  1. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H. … Rovira C. (Cancer Res. 2011) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4633 Gene

Sources for MIR4633 Gene

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