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Aliases for MIR4632 Gene

Subcategory (RNA class) for MIR4632 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4632 Gene

  • MicroRNA 4632 2 3 5
  • Hsa-Mir-4632 3

External Ids for MIR4632 Gene

Previous GeneCards Identifiers for MIR4632 Gene

  • GC01U903265
  • GC01P012253

Summaries for MIR4632 Gene

Entrez Gene Summary for MIR4632 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4632 Gene

MIR4632 (MicroRNA 4632) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4632 Gene

Genomics for MIR4632 Gene

Regulatory Elements for MIR4632 Gene

Enhancers for MIR4632 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01F012188 0.2 ENCODE 0.8 -3.5 -3455 0.2 BCOR SMARCA5 CTCF ZMYM3 KDM1A TNFRSF1B MIR7846 VPS13D MIR4632
GH01F012196 0.8 Ensembl ENCODE 0.4 +5.1 5054 0.9 HDGF CTCF MAX ZNF384 RAD21 FOSL1 POLR2A SMARCA4 ADNP MYC VPS13D GC01P012204 MIR4632
GH01F012199 0.2 ENCODE 0.4 +7.9 7906 0.6 CTCF MTA2 SMC3 REST RAD21 RELA GC01P012204 MIR4632
GH01F012198 0.7 ENCODE 0.4 +6.8 6819 0.3 BCOR REST MNT ZNF18 GC01P012204 MIR4632
GH01F012166 1.6 FANTOM5 Ensembl ENCODE 0.4 -14.5 -14494 21.2 HDGF PKNOX1 CREB3L1 WRNIP1 ARID4B SIN3A YY1 ZNF143 ZNF207 FOS MTHFR TNFRSF1B UBIAD1 TNFRSF8 CLCN6 VPS13D DHRS3 AGTRAP MIIP MFN2
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around MIR4632 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR4632 Gene

Chromosome:
1
Start:
12,191,713 bp from pter
End:
12,191,773 bp from pter
Size:
61 bases
Orientation:
Plus strand

Genomic View for MIR4632 Gene

Genes around MIR4632 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4632 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4632 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4632 Gene

Proteins for MIR4632 Gene

Post-translational modifications for MIR4632 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4632 Gene

Domains & Families for MIR4632 Gene

Gene Families for MIR4632 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4632: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4632 Gene

Function for MIR4632 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4632 Gene

Localization for MIR4632 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4632 Gene

Pathways & Interactions for MIR4632 Gene

SuperPathways for MIR4632 Gene

No Data Available

Interacting Proteins for MIR4632 Gene

Gene Ontology (GO) - Biological Process for MIR4632 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4632 Gene

Transcripts for MIR4632 Gene

mRNA/cDNA for MIR4632 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4632 Gene

No ASD Table

Relevant External Links for MIR4632 Gene

GeneLoc Exon Structure for
MIR4632
ECgene alternative splicing isoforms for
MIR4632

Expression for MIR4632 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4632 Gene:

MIR4632
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR4632 Gene

Orthologs for MIR4632 Gene

Evolution for MIR4632 Gene

ENSEMBL:
Gene Tree for MIR4632 (if available)
TreeFam:
Gene Tree for MIR4632 (if available)

No data available for Orthologs for MIR4632 Gene

Paralogs for MIR4632 Gene

No data available for Paralogs for MIR4632 Gene

Variants for MIR4632 Gene

Sequence variations from dbSNP and Humsavar for MIR4632 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs11121885 -- 12,191,221(+) CTGTT(C/T)ACCCC intron-variant, upstream-variant-2KB
rs111378612 -- 12,191,465(+) ACTGC(A/G)GGGAG intron-variant, upstream-variant-2KB
rs113904142 -- 12,189,826(+) AGGTG(A/G)CATTT intron-variant, upstream-variant-2KB
rs114136735 -- 12,189,762(+) GGCGG(A/G)GGAGA intron-variant, upstream-variant-2KB
rs116259303 -- 12,190,132(+) TCACC(A/G)TCCCT intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR4632 Gene

Variant ID Type Subtype PubMed ID
esv3584475 CNV gain 24956385
nsv469830 CNV loss 16826518
nsv471622 CNV gain+loss 15918152
nsv508891 CNV insertion 20534489
nsv527024 CNV loss 19592680

Relevant External Links for MIR4632 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4632

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4632 Gene

Disorders for MIR4632 Gene

Relevant External Links for MIR4632

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR4632

No disorders were found for MIR4632 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4632 Gene

Publications for MIR4632 Gene

  1. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H. … Rovira C. (Cancer Res. 2011) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4632 Gene

Sources for MIR4632 Gene

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