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Aliases for MIR4632 Gene

Subcategory (RNA class) for MIR4632 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4632 Gene

  • MicroRNA 4632 2 3 5
  • Hsa-Mir-4632 3

External Ids for MIR4632 Gene

Previous GeneCards Identifiers for MIR4632 Gene

  • GC01U903265
  • GC01P012253

Summaries for MIR4632 Gene

Entrez Gene Summary for MIR4632 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4632 Gene

MIR4632 (MicroRNA 4632) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4632 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4632 Gene

Genomics for MIR4632 Gene

GeneHancer (GH) Regulatory Elements for MIR4632 Gene

Promoters and enhancers for MIR4632 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH01I012190 Enhancer 0.6 dbSUPER 550.8 -0.4 -370 1.9 CTCF ZNF263 L3MBTL2 NFXL1 ZFHX2 ZNF341 GLIS1 ZBTB33 ZNF600 EGR2 MIR4632 TNFRSF1B VPS13D
GH01I012166 Promoter/Enhancer 2.6 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 0.4 -17.3 -17298 15.6 HDGF FOXA2 PKNOX1 SMAD1 ARNT IRF4 YY1 ZNF766 ZNF207 ZNF143 TNFRSF1B MTHFR TNFRSF8 CLCN6 VPS13D AGTRAP MIIP MFN2 MIR7846 MIR4632
GH01I012182 Enhancer 1.5 FANTOM5 Ensembl ENCODE dbSUPER 0.4 -6.6 -6601 5.4 RAD21 ZNF366 ZNF143 RCOR1 FOS IKZF2 RUNX3 SMARCA5 RXRA REST TNFRSF1B VPS13D TNFRSF8 AGTRAP MTHFR CLCN6 MIR4632
GH01I012188 Enhancer 0.7 ENCODE dbSUPER 0.8 -3.5 -3454 0.2 SMARCA5 BCOR FOXA2 ZNF143 ZFP36 ZMYM3 TNFRSF1B VPS13D MIR4632
GH01I012200 Enhancer 1.1 ENCODE dbSUPER 0.4 +11.3 11317 4.2 HDAC1 HDGF TCF12 ZNF121 GLIS2 EGR1 ZNF143 ATF7 ETV6 IKZF2 GC01P012204 FBXO44 MIR4632 TNFRSF1B
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR4632 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR4632 Gene

Genomic Locations for MIR4632 Gene
chr1:12,191,713-12,191,773
(GRCh38/hg38)
Size:
61 bases
Orientation:
Plus strand
chr1:12,251,762-12,251,839
(GRCh37/hg19)

Genomic View for MIR4632 Gene

Genes around MIR4632 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4632 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4632 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4632 Gene

Proteins for MIR4632 Gene

Post-translational modifications for MIR4632 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4632 Gene

Domains & Families for MIR4632 Gene

Gene Families for MIR4632 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4632: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4632 Gene

Function for MIR4632 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4632 Gene

Localization for MIR4632 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4632 Gene

Pathways & Interactions for MIR4632 Gene

SuperPathways for MIR4632 Gene

No Data Available

Interacting Proteins for MIR4632 Gene

Gene Ontology (GO) - Biological Process for MIR4632 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4632 Gene

Drugs & Compounds for MIR4632 Gene

No Compound Related Data Available

Transcripts for MIR4632 Gene

mRNA/cDNA for MIR4632 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4632 Gene

No ASD Table

Relevant External Links for MIR4632 Gene

GeneLoc Exon Structure for
MIR4632
ECgene alternative splicing isoforms for
MIR4632

Expression for MIR4632 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4632 Gene:

MIR4632
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4632 Gene

Orthologs for MIR4632 Gene

Evolution for MIR4632 Gene

ENSEMBL:
Gene Tree for MIR4632 (if available)
TreeFam:
Gene Tree for MIR4632 (if available)

No data available for Orthologs for MIR4632 Gene

Paralogs for MIR4632 Gene

No data available for Paralogs for MIR4632 Gene

Variants for MIR4632 Gene

Sequence variations from dbSNP and Humsavar for MIR4632 Gene

SNP ID Clin Chr 01 pos Variation AA Info Type
rs1002907379 -- 12,191,655(+) C/A upstream_transcript_variant
rs1005356529 -- 12,189,773(+) C/T upstream_transcript_variant
rs1006435748 -- 12,192,187(+) A/G downstream_transcript_variant
rs1007996629 -- 12,191,258(+) A/G upstream_transcript_variant
rs1008276793 -- 12,191,429(+) G/C upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR4632 Gene

Variant ID Type Subtype PubMed ID
esv3584475 CNV gain 24956385
nsv469830 CNV loss 16826518
nsv471622 CNV gain+loss 15918152
nsv508891 CNV insertion 20534489
nsv527024 CNV loss 19592680

Additional Variant Information for MIR4632 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4632

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4632 Gene

Disorders for MIR4632 Gene

Additional Disease Information for MIR4632

No disorders were found for MIR4632 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4632 Gene

Publications for MIR4632 Gene

  1. miR-4632 mediates PDGF-BB-induced proliferation and antiapoptosis of human pulmonary artery smooth muscle cells via targeting cJUN. (PMID: 28701355) Qian Z … Gou D (American journal of physiology. Cell physiology 2017) 3 58
  2. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H … Rovira C (Cancer research 2011) 3 58
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR4632 Gene

Sources for MIR4632 Gene

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