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Aliases for MIR455 Gene

Subcategory (RNA class) for MIR455 Gene


Quality Score for this RNA gene is


Aliases for MIR455 Gene

  • MicroRNA 455 2 3 5
  • Hsa-Mir-455 3
  • Mir-455 3
  • MIRN455 3

External Ids for MIR455 Gene

ORGUL Members for MIR455 Gene

Previous HGNC Symbols for MIR455 Gene

  • MIRN455

Previous GeneCards Identifiers for MIR455 Gene

  • GC09P116012
  • GC09P116971

Summaries for MIR455 Gene

Entrez Gene Summary for MIR455 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR455 Gene

MIR455 (MicroRNA 455) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR455 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR455 Gene

Genomics for MIR455 Gene

GeneHancer (GH) Regulatory Elements for MIR455 Gene

Promoters and enhancers for MIR455 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH09I114169 Enhancer 1.6 FANTOM5 Ensembl ENCODE dbSUPER 12.3 -35.7 -35674 9.5 PKNOX1 MLX ARID4B DMAP1 ZNF48 ETS1 YY1 FOS RXRA SP5 COL27A1 PRPF4 MIR455 ORM1 GC09P114665 GC09P114317 GC09P114318
GH09I114237 Enhancer 1.3 Ensembl ENCODE dbSUPER 12.5 +29.7 29653 3.2 HDAC1 FOXA2 SMAD1 ATF1 RAD21 YY1 TCF12 GATA2 RCOR1 ATF7 MIR455 COL27A1 KIF12 LOC105376224
GH09I114162 Enhancer 1.2 Ensembl ENCODE dbSUPER 11.3 -45.7 -45705 2 ELF3 MLX ARID4B SIN3A ZNF48 ZSCAN9 RAD21 RARA YY1 THAP11 COL27A1 MIR455 GC09P114665 LOC105376225
GH09I114180 Enhancer 0.9 Ensembl ENCODE dbSUPER 12.4 -28.1 -28052 2.4 RXRA ZNF189 HNF4G HNF4A COL27A1 MIR455 GC09P114665 GC09P114318 GC09P114317
GH09I114249 Enhancer 0.9 Ensembl ENCODE dbSUPER 11.3 +40.8 40769 1.7 FOXA2 POLR2A RCOR1 HNF4A RAD21 MIR455 COL27A1 ATP6V1G1 LOC105376224
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR455 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR455 Gene

Genomic Locations for MIR455 Gene
96 bases
Plus strand

Genomic View for MIR455 Gene

Genes around MIR455 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR455 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR455 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR455 Gene

Proteins for MIR455 Gene

Post-translational modifications for MIR455 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR455 Gene

Domains & Families for MIR455 Gene

Gene Families for MIR455 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR455: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR455 Gene

Function for MIR455 Gene

Phenotypes From GWAS Catalog for MIR455 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR455 Gene

Localization for MIR455 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR455 Gene

Pathways & Interactions for MIR455 Gene

SuperPathways for MIR455 Gene

No Data Available

Interacting Proteins for MIR455 Gene

Gene Ontology (GO) - Biological Process for MIR455 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR455 Gene

Drugs & Compounds for MIR455 Gene

No Compound Related Data Available

Transcripts for MIR455 Gene

mRNA/cDNA for MIR455 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR455 Gene

No ASD Table

Relevant External Links for MIR455 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR455 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR455 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR455 Gene:

genes like me logo Genes that share expression patterns with MIR455: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR455 Gene

Orthologs for MIR455 Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR455 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia bta-mir-455 34
  • 100 (a)
(Canis familiaris)
Mammalia cfa-mir-455 34
  • 100 (a)
(Pan troglodytes)
Mammalia ptr-mir-455 34
  • 100 (a)
(Monodelphis domestica)
Mammalia mdo-mir-455 34
  • 95 (a)
(Mus musculus)
Mammalia Mir455 34
  • 93 (a)
(Gallus gallus)
Aves gga-mir-455 34
  • 97 (a)
(Anolis carolinensis)
Reptilia aca-mir-455 34
  • 93 (a)
(Danio rerio)
Actinopterygii dre-mir-455b 34
  • 81 (a)
Species where no ortholog for MIR455 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MIR455 Gene

Gene Tree for MIR455 (if available)
Gene Tree for MIR455 (if available)

Paralogs for MIR455 Gene

No data available for Paralogs for MIR455 Gene

Variants for MIR455 Gene

Sequence variations from dbSNP and Humsavar for MIR455 Gene

SNP ID Clin Chr 09 pos Variation AA Info Type
rs1001801800 -- 114,209,442(+) G/A non_coding_transcript_variant
rs1002834690 -- 114,208,241(+) C/T upstream_transcript_variant
rs1003017557 -- 114,208,579(+) A/G upstream_transcript_variant
rs1003375114 -- 114,208,326(+) C/T upstream_transcript_variant
rs1004705086 -- 114,209,129(+) G/A upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR455 Gene

Variant ID Type Subtype PubMed ID
dgv12859n54 CNV gain 21841781
dgv33e196 CNV duplication 17116639
dgv7706n100 CNV gain 25217958
dgv948n27 CNV gain 19166990
esv2761285 CNV gain 21179565
esv3621549 CNV gain 21293372
nsv615233 CNV gain 21841781

Additional Variant Information for MIR455 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR455 Gene

Disorders for MIR455 Gene

Additional Disease Information for MIR455

No disorders were found for MIR455 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR455 Gene

Publications for MIR455 Gene

  1. miR-455-3p serves as prognostic factor and regulates the proliferation and migration of non-small cell lung cancer through targeting HOXB5. (PMID: 29170127) Gao X … Zhang M (Biochemical and biophysical research communications 2018) 3 58
  2. MicroRNA-455-3p promotes invasion and migration in triple negative breast cancer by targeting tumor suppressor EI24. (PMID: 28038450) Li Z … Li L (Oncotarget 2017) 3 58
  3. miR-455 inhibits breast cancer cell proliferation through targeting CDK14. (PMID: 28300591) Wang B … Tan T (European journal of pharmacology 2017) 3 58
  4. MicroRNA-455-3p functions as a tumor suppressor by targeting eIF4E in prostate cancer. (PMID: 28350134) Zhao Y … Jiang H (Oncology reports 2017) 3 58
  5. MicroRNA-455 suppresses the oncogenic function of HDAC2 in human colorectal cancer. (PMID: 28538837) Mao QD … Liu XS (Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 2017) 3 58

Products for MIR455 Gene

Sources for MIR455 Gene

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