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Aliases for MIR4539 Gene

Subcategory (RNA class) for MIR4539 Gene


Quality Score for this RNA gene is


Aliases for MIR4539 Gene

  • MicroRNA 4539 2 3 5
  • Hsa-Mir-4539 3

External Ids for MIR4539 Gene

Previous GeneCards Identifiers for MIR4539 Gene

  • GC14U901284
  • GC14M107726
  • GC14M105926
  • GC14M105985

Summaries for MIR4539 Gene

Entrez Gene Summary for MIR4539 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4539 Gene

MIR4539 (MicroRNA 4539) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4539 Gene

Genomics for MIR4539 Gene

Regulatory Elements for MIR4539 Gene

Promoters for MIR4539 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around MIR4539 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR4539 Gene

105,857,513 bp from pter
105,857,572 bp from pter
60 bases
Minus strand

Genomic View for MIR4539 Gene

Genes around MIR4539 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4539 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4539 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4539 Gene

Proteins for MIR4539 Gene

Post-translational modifications for MIR4539 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4539 Gene

Domains & Families for MIR4539 Gene

Gene Families for MIR4539 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4539: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4539 Gene

Function for MIR4539 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4539 Gene

Localization for MIR4539 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4539 Gene

Pathways & Interactions for MIR4539 Gene

SuperPathways for MIR4539 Gene

No Data Available

Interacting Proteins for MIR4539 Gene

Gene Ontology (GO) - Biological Process for MIR4539 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR4539 Gene

Drugs & Compounds for MIR4539 Gene

No Compound Related Data Available

Transcripts for MIR4539 Gene

mRNA/cDNA for MIR4539 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4539 Gene

No ASD Table

Relevant External Links for MIR4539 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR4539 Gene

mRNA expression in normal human tissues for MIR4539 Gene

genes like me logo Genes that share expression patterns with MIR4539: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MIR4539 Gene

Orthologs for MIR4539 Gene

Evolution for MIR4539 Gene

Gene Tree for MIR4539 (if available)
Gene Tree for MIR4539 (if available)

No data available for Orthologs for MIR4539 Gene

Paralogs for MIR4539 Gene

No data available for Paralogs for MIR4539 Gene

Variants for MIR4539 Gene

Sequence variations from dbSNP and Humsavar for MIR4539 Gene

SNP ID Clin Chr 14 pos Sequence Context AA Info Type
rs2879220 -- 105,857,565(-) AGCTG(A/G)GCTCT nc-transcript-variant
rs9707626 -- 105,857,507(+) agccc(A/G)gctca downstream-variant-500B
rs36191074 -- 105,857,356(+) CAGCT(C/T)AGCCC downstream-variant-500B
rs34563447 -- 105,857,185(+) CCAGT(A/T)TAGCC downstream-variant-500B
rs147639672 -- 105,857,549(+) CTCAG(C/T)ACAGC nc-transcript-variant

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) , Variation tolerance and Relevant External Links for MIR4539 Gene

Disorders for MIR4539 Gene

Relevant External Links for MIR4539

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR4539 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4539 Gene

Publications for MIR4539 Gene

  1. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima D.D. … Dave S.S. (Blood 2010) 3 67
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3

Products for MIR4539 Gene

Sources for MIR4539 Gene