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Aliases for MIR4536-1 Gene

Subcategory (RNA class) for MIR4536-1 Gene


Quality Score for this RNA gene is


Aliases for MIR4536-1 Gene

  • MicroRNA 4536-1 2 3
  • Hsa-Mir-4536-1 3 5
  • MicroRNA 4536 2 3
  • Hsa-Mir-4536 3
  • MIR4536 3

External Ids for MIR4536-1 Gene

Previous HGNC Symbols for MIR4536-1 Gene

  • MIR4536

Previous GeneCards Identifiers for MIR4536-1 Gene

  • GC0XU901770
  • GC0XP055481

Summaries for MIR4536-1 Gene

Entrez Gene Summary for MIR4536-1 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4536-1 Gene

MIR4536-1 (MicroRNA 4536-1) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4536-1 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4536-1 Gene

Genomics for MIR4536-1 Gene

Regulatory Elements for MIR4536-1 Gene

Promoters for MIR4536-1 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000246769 -1018 2400 PKNOX1 MXI1 MAX ZBTB40 RAD21 E2F1 ZNF316 POLR2A ETV6 RUNX3

Genomic Locations for MIR4536-1 Gene

Genomic Locations for MIR4536-1 Gene
88 bases
Minus strand

Genomic View for MIR4536-1 Gene

Genes around MIR4536-1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4536-1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4536-1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4536-1 Gene

Proteins for MIR4536-1 Gene

Post-translational modifications for MIR4536-1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4536-1 Gene

Domains & Families for MIR4536-1 Gene

Gene Families for MIR4536-1 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4536-1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4536-1 Gene

Function for MIR4536-1 Gene

Phenotypes From GWAS Catalog for MIR4536-1 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4536-1 Gene

Localization for MIR4536-1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4536-1 Gene

Pathways & Interactions for MIR4536-1 Gene

SuperPathways for MIR4536-1 Gene

No Data Available

Interacting Proteins for MIR4536-1 Gene

Gene Ontology (GO) - Biological Process for MIR4536-1 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR4536-1 Gene

Drugs & Compounds for MIR4536-1 Gene

No Compound Related Data Available

Transcripts for MIR4536-1 Gene

mRNA/cDNA for MIR4536-1 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4536-1 Gene

No ASD Table

Relevant External Links for MIR4536-1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR4536-1 Gene

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4536-1 Gene

Orthologs for MIR4536-1 Gene

Evolution for MIR4536-1 Gene

Gene Tree for MIR4536-1 (if available)
Gene Tree for MIR4536-1 (if available)

No data available for Orthologs for MIR4536-1 Gene

Paralogs for MIR4536-1 Gene

No data available for Paralogs for MIR4536-1 Gene

Variants for MIR4536-1 Gene

Sequence variations from dbSNP and Humsavar for MIR4536-1 Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type
rs1000343355 -- 55,451,666(+) ACAAT(A/G)TTATC downstream-variant-500B, upstream-variant-2KB
rs1005481725 -- 55,453,577(+) TGCGC(A/T)TTTTC downstream-variant-500B, upstream-variant-2KB
rs1005933950 -- 55,453,026(+) ATTCC(G/T)CCCCT upstream-variant-2KB, reference, missense
rs1006126666 -- 55,453,488(+) GCTGT(G/T)GTGTG upstream-variant-2KB, utr-variant-3-prime
rs1010171540 -- 55,451,765(+) AAGAC(A/G)GGAAA downstream-variant-500B, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR4536-1 Gene

Variant ID Type Subtype PubMed ID
nsv7448 OTHER inversion 18451855
nsv469510 CNV gain 16826518
nsv435891 CNV deletion 17901297
esv2740175 CNV deletion 23290073

Relevant External Links for MIR4536-1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4536-1 Gene

Disorders for MIR4536-1 Gene

Relevant External Links for MIR4536-1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR4536-1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4536-1 Gene

Publications for MIR4536-1 Gene

  1. Genome-wide association study of smoking behaviours among Bangladeshi adults. (PMID: 24665060) Argos M … Ahsan H (Journal of medical genetics 2014) 3 60
  2. miRDeep2 accurately identifies known and hundreds of novel microRNA genes in seven animal clades. (PMID: 21911355) Friedländer MR … Rajewsky N (Nucleic acids research 2012) 3 60
  3. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima DD … Hematologic Malignancies Research Consortium (Blood 2010) 3 60
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 60

Products for MIR4536-1 Gene

Sources for MIR4536-1 Gene

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