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Aliases for MIR4536-1 Gene

Subcategory (RNA class) for MIR4536-1 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4536-1 Gene

  • MicroRNA 4536-1 2 3
  • MicroRNA 4536 2 3
  • Hsa-Mir-4536-1 3
  • Hsa-Mir-4536 3
  • MIR4536 3

External Ids for MIR4536-1 Gene

Previous HGNC Symbols for MIR4536-1 Gene

  • MIR4536

Previous GeneCards Identifiers for MIR4536-1 Gene

  • GC0XU901770

Summaries for MIR4536-1 Gene

Entrez Gene Summary for MIR4536-1 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4536-1 Gene

MIR4536-1 (MicroRNA 4536-1) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4536-1 Gene

Genomics for MIR4536-1 Gene

Genomic Location for MIR4536-1 Gene

Start:
55,451,460 bp from pter
End:
55,451,585 bp from pter
Size:
126 bases
Orientation:
Plus strand

Genomic View for MIR4536-1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR4536-1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4536-1 Gene

No data available for Regulatory Elements for MIR4536-1 Gene

Proteins for MIR4536-1 Gene

Post-translational modifications for MIR4536-1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4536-1 Gene

Domains for MIR4536-1 Gene

Gene Families for MIR4536-1 Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4536-1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4536-1 Gene

Function for MIR4536-1 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR4536-1 Gene

Localization for MIR4536-1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4536-1 Gene

Pathways for MIR4536-1 Gene

SuperPathways for MIR4536-1 Gene

No Data Available

Interacting Proteins for MIR4536-1 Gene

Gene Ontology (GO) - Biological Process for MIR4536-1 Gene

None

No data available for Pathways by source for MIR4536-1 Gene

Transcripts for MIR4536-1 Gene

mRNA/cDNA for MIR4536-1 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4536-1 Gene

No ASD Table

Relevant External Links for MIR4536-1 Gene

GeneLoc Exon Structure for
MIR4536-1
ECgene alternative splicing isoforms for
MIR4536-1

Expression for MIR4536-1 Gene

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for MIR4536-1 Gene

Orthologs for MIR4536-1 Gene

Evolution for MIR4536-1 Gene

ENSEMBL:
Gene Tree for MIR4536-1 (if available)
TreeFam:
Gene Tree for MIR4536-1 (if available)

No data available for Orthologs for MIR4536-1 Gene

Paralogs for MIR4536-1 Gene

No data available for Paralogs for MIR4536-1 Gene

Variants for MIR4536-1 Gene

Sequence variations from dbSNP and Humsavar for MIR4536-1 Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type MAF
rs4826404 -- 55,449,732(+) CATGC(A/G)CACAA upstream-variant-2KB
rs12688603 -- 55,449,944(+) GACGT(A/G)CTTTA upstream-variant-2KB
rs112822157 -- 55,449,502(+) AATAA(C/T)ATTCA upstream-variant-2KB
rs139782911 -- 55,450,022(+) TGGGC(A/G)TAATT upstream-variant-2KB
rs184673426 -- 55,450,001(+) GCAAA(G/T)ATATA upstream-variant-2KB

Relevant External Links for MIR4536-1 Gene

HapMap Linkage Disequilibrium report
MIR4536-1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for MIR4536-1 Gene

Disorders for MIR4536-1 Gene

No disorders were found for MIR4536-1 Gene.

No data available for UniProtKB/Swiss-Prot for MIR4536-1 Gene

Publications for MIR4536-1 Gene

  1. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  2. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima D.D. … Dave S.S. (Blood 2010) 3
  3. miRDeep2 accurately identifies known and hundreds of novel microRNA genes in seven animal clades. (PMID: 21911355) FriedlAonder M.R. … Rajewsky N. (Nucleic Acids Res. 2012) 3
  4. Genome-wide association study of smoking behaviours among Bangladeshi adults. (PMID: 24665060) Argos M. … Ahsan H. (J. Med. Genet. 2014) 3

Products for MIR4536-1 Gene

Sources for MIR4536-1 Gene

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